Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair

Shilin LIAN; Mengtao WU; Wenping HU; Chao SONG; Qingsheng LU

doi:10.16016/j.1000-5404.201906139

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Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair

Monographic Reports | 更新时间：2026-01-09

- Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair
- Journal of Third Military Medical University Vol. 41, Issue 24, Pages: 2375-2379(2019)
- 作者机构：
  
  1.200433 上海，海军军医大学:基础医学院
  2.250000 济南，山东大学第二医院血管外科
  3.200433 上海，海军军医大学:附属长海医院血管外科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201906139
  CLC： R181.32;R619;R654.3
- Received：19 June 2019，
  
  Revised：2019-10-17，
  
  Published：30 December 2019
- 稿件说明：
移动端阅览
Shilin LIAN, Mengtao WU, Wenping HU, et al. Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair[J]. Journal of Third Military Medical University, 2019, 41(24): 2375-2379.
DOI：

Shilin LIAN, Mengtao WU, Wenping HU, et al. Post-endovascular aortic repair syndrome: risk factor analysis of endovascular aneurysm repair[J]. Journal of Third Military Medical University, 2019, 41(24): 2375-2379. DOI： 10.16016/j.1000-5404.201906139.

摘要

目的

探讨主动脉瘤腔内修复术(endovascular aneurysm repair

EVAR)后早期不良事件的危险因素。

方法

通过对1997-2014年于我院就诊的2 193例主动脉瘤患者临床资料进行回顾性研究，运用多因素Logistic回归分析出现EVAR术后早期不良事件(early postoperative adverse events

EPAE)患者的围手术期血液学指标。

结果

术后早期不良事件的发生率为20.8%。多因素Logistic回归分析结果显示，术后白细胞计数(

=1.24

95%

:1.06-1.16，

=0.008)、血红蛋白水平(

=0.87，95%

:0.83-0.92，

0.001)和血小板水平(

=0.99，95%

: 0.98-1.00，

=0.029)的优势比有统计学意义。

结论

术后白细胞升高、血红蛋白下降和血小板下降是与EPAE相关的独立危险因素。

Abstract

Objective

To investigate the risk factors for early postoperative adverse events (EPAE) after endovascular aneurysm repair (EVAR).

Methods

A total of 2 193 cases of aortic aneurysm treated in Changhai Hospitaly from 1997 to 2014 were analyzed retrospectively. The perioperative hematological variables in relation to EPAE after EVAR were analyzed.

Results

The rate of EPAE was 20.8%. Multivariate analysis showed postoperative white cell count (

=1.24

95%

: 1.06-1.16

=0.08)

hemoglobin level (

=0.87

95%

: 0.83-0.92

0.01)

and platelet level (

=0.99

95%

: 0.98-1.00

=0.029) to be independent factors associated with the EPAE.

Conclusion

Increased white cell count and decreased hemoglobin and platelet levels are independent risk factors for EPAE.

关键词

Keywords

references

PARAVASTU S C, JAYARAJASINGAM R, COTTAM R, et al . Endovascular repair of abdominal aortic aneurysm[J ] . Cochrane Database Syst Rev, 2014(1): CD004178. DOI: 10.1002/14651858.CD004178.pub2.

PARSA C J, WILLIAMS J B, BHATTACHARYA S D, et al . Midterm results with thoracic endovascular aortic repair for chronic type B aortic dissection with associated aneurysm[J ] . J Thorac Cardiovasc Surg, 2011, 141(2): 322-327. DOI: 10.1016/j.jtcvs.2010.10.043.

MASTRACCI T M, EAGLETON M J, KURAMOCHI Y, et al . Twelve-year results of fenestratedendografts for juxtarenal and group Ⅳ thoracoabdominal aneurysms[J ] . J Vasc Surg, 2015, 61(2): 355-364. DOI: 10.1016 /j.jvs.2014.09.068.

BLUM U, VOSHAGE G, LAMMER J, et al . Endoluminal stent-grafts for infrarenal abdominal aortic aneurysms[J ] . N Engl J Med, 1997, 336(1): 13-20. DOI: 10.1056/NEJM199701023360103.

CHANG C K, CHUTER T A, NIEMANN C U, et al . Systemic inflammation, coagulopathy, and acute renal insufficiency following endovascular thoracoabdominal aortic aneurysm repair[J ] . J Vasc Surg, 2009, 49(5): 1140-1146. DOI: 10.1016/j.jvs.2008.11.102.

PARODI J C, PALMAZ J C, BARONE H D. Transfemoral intraluminal graft implantation for abdominal aortic aneurysms[J]. Ann Vasc Surg, 1991, 5(6): 491-499. DOI: 10.1007/BF02015271.

ARNAOUTOGLOU E, KOUVELOS G, MILIONIS H, et al . Post-implantation syndrome following endovascular abdominal aortic aneurysm repair: preliminary data[J ] . Interact Cardiovasc Thorac Surg, 2011, 12(4): 609-614. DOI: 10.1510/icvts.2010.256784.

ARNAOUTOGLOU E, KOUVELOS G, PAPA N, et al . Prospective evaluation of postimplantation syndrome evolution on patient outcomes after endovascular aneurysm repair for abdominal aortic aneurysm[J ] . J Vasc Surg, 2016, 63( 5): 1248-1255. DOI: 10.1016/j.jvs.2015.11.043.

ARNAOUTOGLOU E, KOUVELOS G, PAPA N, et al . Prospective evaluation of post-implantation inflammatory response after EVAR for AAA: influence on patients' 30 day outcome[J ] . Eur J Vasc Endovasc Surg, 2015, 49(2): 175-183. DOI: 10.1016/j.ejvs.2014.12.006.

KAKISIS J D, MOULAKAKIS K G, ANTONOPOULOS C N, et al . Volume of new-onset thrombus is associated with the development ofpostimplantation syndrome after endovascular aneurysm repair[J ] . J Vasc Surg, 2014, 60(5): 1140-1145. DOI: 10.1016/j.jvs.2014.05.041.

HOSHINA K, HOSAKA A, TAKAYAMA T, et al . Outcomes after open surgery and endovascular aneurysm repair for abdominal aortic aneurysm in patients with massive neck atheroma[J ] . Eur J Vasc Endovasc Surg, 2012, 43(3): 257-261. DOI: 10.1016/j.ejvs.2011.11.023.

SHIMAZAKI T, ISHIMARU S, KAWAGUCHI S, et al . Blood coagulation and fibrinolytic response after endovascular stent grafting of thoracic aorta[J ] . J Vasc Surg, 2003, 37(6): 1213-1218. DOI: 10.1016/s0741-5214(02)75323-8.

MONACO M, DI TOMMASO L, STASSANO P, et al . Impact of blood coagulation and fibrinolytic system changes on early and mid term clinical outcome in patients undergoing stent endografting surgery[J ] . Interact Cardiovasc Thorac Surg, 2006, 5(6): 724-728. DOI: 10.1510/icvts.2006.136507.

ABDELHAMID M F, DAVIES R S, VOHRA R K, et al . Effect of endovascular and open abdominal aortic aneurysm repair on thrombin generation and fibrinolysis[J ] . J Vasc Surg, 2013, 57(1): 103-107. DOI: 10.1016/j.jvs.2012.07.024.

KWON H, KO G Y, KIM M J, et al . Effects of postimplantation systemic inflammatory response on long-term clinical outcomes after endovascular aneurysm repair of an abdominal aortic aneurysm[J ] . Medicine (Baltimore), 2016, 95(32): e4532. DOI: 10.1097/MD.0000000000004532.

CROSS K S, BOUCHIER-HAYES D, LEAHY A L. Consumptive coagulopathy following endovascular stent repair of abdominal aortic aneurysm[J]. Eur J Vasc Endovasc Surg, 2000, 19(1): 94-95. DOI: 10.1053/ejvs.1999.0970.

ARNAOUTOGLOU E, PAPAS N, MILIONIS H, et al . Post-implantation syndrome after endovascular repair of aortic aneurysms: need for postdischarge surveillance[J ] . Interac Cardiovasc Thoracic Surg, 2010, 11(4): 449-454.

AHO P S, NIEMI T, PⅡLONEN A, et al . Interplay between coagulation and inflammation in open and endovascular abdominal aortic aneurysm repair: impact of intra-aneurysmal thrombus[J ] . Scand J Surg, 2007, 96(3): 229-235. DOI: 10.1177/145749690709600308.

NESSVI OTTERHAG S, GOTTSÄTER A, ACOSTA S, et al . Inflammatory mediators after endovascular aortic aneurysm repair[J ] . Cytokine, 2014, 70(2): 151-155. DOI: 10.1016/j.cyto.2014.07.256.

DIEHM N, BENENATI J F, BECKER G J, et al . Anemia is associated with abdominal aortic aneurysm (AAA) size and decreased long-term survival after endovascular AAA repair[J ] . J Vasc Surg, 2007, 46(4): 676-681. DOI: 10.1016/j.jvs.2007.06.027.

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