Application and progress of stem cells in male infertility

Wei TANG; Daixing HU

doi:10.16016/j.1000-5404.201905188

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Application and progress of stem cells in male infertility

Expert Reviews | 更新时间：2026-01-09

- Application and progress of stem cells in male infertility
- Journal of Third Military Medical University Vol. 41, Issue 19, Pages: 1897-1901(2019)
- 作者机构：
  
  400016 重庆，重庆医科大学附属第一医院泌尿外科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201905188
  CLC： R329.2;R698.2
- Received：29 May 2019，
  
  Revised：2019-09-01，
  
  Published：15 October 2019
- 稿件说明：
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Wei TANG, Daixing HU. Application and progress of stem cells in male infertility[J]. Journal of Third Military Medical University, 2019, 41(19): 1897-1901.
DOI：

Wei TANG, Daixing HU. Application and progress of stem cells in male infertility[J]. Journal of Third Military Medical University, 2019, 41(19): 1897-1901. DOI： 10.16016/j.1000-5404.201905188.

摘要

目前干细胞已成为医学研究的热点，并逐渐从基础研究向临床应用方面转化。多种干细胞在男性不育领域的研究已取得较多进展，如精原干细胞(spermatagonial stem cells，SSCs)、间充质干细胞(mesenchymal stem cells，MSCs)、胚胎干细胞(embryonic stem cells，ESCs)和诱导多潜能干细胞(induced pluripotent stem cells，iPSCs)，但仍然存在一些问题和挑战，如安全性、有效性、伦理、法律、市场监管等诸多方面。现就干细胞在男性不育领域的相关研究和进展进行评述，为干细胞更合理地应用于男性不育治疗提供参考。

Abstract

Researches concerning stem cells have made great progresses

and become a hot spot in medical sciences

which has gradually transformed from basic research to clinical application. Many types of stem cells were used in male infertility

including spermatogonia stem cells (SSCs)

mesenchymal stem cells (MSCs)

embryonic stem cells (ESCs)

and induced pluripotent stem cells (iPSCs). However

there are still some problems and challenges

such as safety

effectiveness

ethics

law

market regulation and other aspects. This article reviews the research and progress of stem cells

and provides reference for the application of stem cells more rationally in the field of male infertility.

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Keywords

references

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