Development and efficiency of a noninvasive positive pressure ventilation <italic style="font-style: italic">via</italic> face mask with 2 channels and constant leakage

Tao HUANG; Hua WANG; Qin XU

doi:10.16016/j.1000-5404.201905009

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Development and efficiency of a noninvasive positive pressure ventilation via face mask with 2 channels and constant leakage

Biomedical Engineering | 更新时间：2026-01-09

- Development and efficiency of a noninvasive positive pressure ventilation via face mask with 2 channels and constant leakage
- Journal of Third Military Medical University Vol. 42, Issue 4, Pages: 421-426(2020)
- 作者机构：
  
  1.400016 重庆，重庆医科大学:附属第一医院重症医学科
  2.400016 重庆，重庆医科大学:生物医学工程学院
  3.400010 重庆，重庆医科大学附属第二医院老年科
- 作者简介：
- 基金信息：
  
  the Medical Research Project funded jointly by Chongqing Science and Technology Commission and Chongqing Health Committee(2019MSXM002)
- DOI：10.16016/j.1000-5404.201905009
  CLC： R197.39; R605.973
- Received：05 May 2019，
  
  Revised：2019-07-08，
  
  Published：28 February 2020
- 稿件说明：
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Tao HUANG, Hua WANG, Qin XU. Development and efficiency of a noninvasive positive pressure ventilation via face mask with 2 channels and constant leakage[J]. Journal of Third Military Medical University, 2020, 42(4): 421-426.
DOI：

Tao HUANG, Hua WANG, Qin XU. Development and efficiency of a noninvasive positive pressure ventilation via face mask with 2 channels and constant leakage[J]. Journal of Third Military Medical University, 2020, 42(4): 421-426. DOI： 10.16016/j.1000-5404.201905009.

摘要

目的

探讨一种具有双通道恒定泄气量功能(two channels and constant leakage，TCCL)的无创正压通气(noninvasive positive pressure ventilation，NPPV)面罩研制及应用效果。

方法

完成TCCL面罩的发明设计、三维构建和产品制造。利用24例健康人进行NPPV试验，根据不同的NPPV面罩类型，按随机数字表法分为2组:研究组采用TCCL面罩；对照组采用普通型NPPV面罩。标准化实验条件下，呼气气道正压(expiratory positive airway pressure

EPAP)为5、10 cmH

O时，监测两组面罩内呼气末二氧化碳分压(pressure of end-tidal carbon dioxide，PetCO

)变化；测试呼吸机吸入气体氧气浓度(FiO

)分别为30%、50%，且吸气气道正压(inspiratory positive airway pressure

IPAP)分别为10、20 cmH

O时，监测面罩内FiO

变化。

结果

标准化试验条件下，相同EPAP水平(5 cmH

O或10 cmH

O)时，研究组面罩内PetCO

均显著低于对照组(

0.05)；相同FiO

水平(FiO

为30%或50%)及IPAP为10、20 cmH

O时，两组组内及组间面罩内FiO

比较差异均无统计学意义。

结论

TCCL面罩对面罩内CO

的清除效果优于普通型NPPV面罩且不影响吸入气体O

浓度。

Abstract

Objective

To explore the preparation and efficiency of a positive pressure ventilation (NPPV)

via

face mask with 2 channels and constant leakage function (TCCL).

Methods

The NPPV-TCCL

via

face mask was invented

designed

three-

dimensionally constructed and manufactured by our team. Twenty-four healthy individuals were recruited and randomly divided into the test group and the control group to wear our produced NPPV-TCCL

via

face mask and conventional NPPV via face mask

respectively. Under standard experimental conditions with expiratory positive airway pressure (EPAP) of 5 and 10 cmH

the pressure of end-tidal carbon dioxide (PetCO

) was monitored in the mask. The inspired oxygen fraction (FiO

) was monitored in the mask when the FiO

parameters of the ventilator were set to 30% and 50%

and inspiratory positive airway pressure (IPAP) was 10 and 20 cmH

O respectively.

Results

Under standard experimental conditions and at the same level of EPAP (5 or 10 cmH

the PetCO

in the mask was significantly lower in the test group than the control group (all

0.05). At the same level of FiO

(30% or 50%) and IPAP=10 or 20cmH

there was no significant difference in FiO

between the 2 groups (

0.05).

Conclusion

NPPV-TCCL

via

face mask is superior to conventional NPPV mask in eliminating CO

and having no effect on FiO

关键词

Keywords

references

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Development and efficiency of a noninvasive positive pressure ventilation via face mask with 2 channels and constant leakage

DOI：10.16016/j.1000-5404.201905009

摘要

Abstract

关键词

Keywords

references