Reproductive outcomes of women with cesarean scar pregnancy after uterine artery chemoembolization combined with evacuation

Tingting TAN; Qiulei SUN; Li LUO; Xi XIONG; Jinhong XIANG; Ping YAN; Chunyan GAO; Zhengqiong CHEN

doi:10.16016/j.1000-5404.201904016

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Reproductive outcomes of women with cesarean scar pregnancy after uterine artery chemoembolization combined with evacuation

Clinical Medicine | 更新时间：2026-01-09

- Reproductive outcomes of women with cesarean scar pregnancy after uterine artery chemoembolization combined with evacuation
- Journal of Third Military Medical University Vol. 41, Issue 17, Pages: 1672-1676(2019)
- 作者机构：
  
  400037 重庆，陆军军医大学(第三军医大学)第二附属医院妇产科
- 作者简介：
- 基金信息：
  
  the Combined Key Project of Chongqing Science and Technology Commission and Chongqing Health Commission(2018ZDXM034);the Research Foundation of the Second Affiliated Hospital of Army Medical University (Third Military Medical University)(2016YLC28)
- DOI：10.16016/j.1000-5404.201904016
  CLC： R619.6;R714.1;R714.22
- Received：02 April 2019，
  
  Revised：2019-05-25，
  
  Published：15 September 2019
- 稿件说明：
移动端阅览
Tingting TAN, Qiulei SUN, Li LUO, et al. Reproductive outcomes of women with cesarean scar pregnancy after uterine artery chemoembolization combined with evacuation[J]. Journal of Third Military Medical University, 2019, 41(17): 1672-1676.
DOI：

Tingting TAN, Qiulei SUN, Li LUO, et al. Reproductive outcomes of women with cesarean scar pregnancy after uterine artery chemoembolization combined with evacuation[J]. Journal of Third Military Medical University, 2019, 41(17): 1672-1676. DOI： 10.16016/j.1000-5404.201904016.

摘要

目的

回顾性分析子宫动脉栓塞化疗(uterine artery chemoembolization，UACE)联合清宫术治疗后，剖宫产瘢痕妊娠(cesarean scar pregnancy，CSP)患者再次妊娠情况，探索复发性剖宫产瘢痕妊娠(recurrent cesarean scar pregnancy

RCSP)发病的影响因素。

方法

收集2010年1月至2017年12月于我院诊断为CSP并接受UACE联合清宫术治疗的患者病例资料及随访信息，分析其再次妊娠情况，并对比正常宫内妊娠和RCSP的临床和超声影像学特点。

结果

有随访资料的396例患者中，118例(29.8%)术后有妊娠计划，96例成功妊娠，妊娠次数104次(88.1%)；其中正常妊娠生产62人次(59.6%)，RCSP 26人次(25.0%)。278例(70.2%)患者术后无妊娠计划，42例患者再次妊娠，妊娠次数47人次(16.9%)；其中正常妊娠生产2人次(4.3%)，RCSP 6人次(12.7%)。在所有妊娠中，RCSP的发生率达21.2%(32/151)。RCSP组患者流产次数较正常宫内妊娠组多(

=0.029)，前次CSP妊娠孕龄较正常宫内妊娠组大(

=0.020)

子宫下段剩余肌层厚度较正常宫内组薄(

=0.010)。

结论

CSP患者经UACE联合清宫术治疗后可再次妊娠。CSP术后再次妊娠易形成RCSP。患者流产次数、前次CSP孕龄和子宫下段剩余肌层厚度与RCSP发生相关。

Abstract

Objective

To retrospectively analyze the reproductive outcome of patients after undergoing uterine artery chemoembolization (UACE) due to cesarean scar pregnancy (CSP)

and to explore the risk factors for CSP.

Methods

The clinical data and follow-up information were retrospectively collected from the women who had diagnosed with CSPs and treated by UACE combined with evacuation in our hospital between January 2010 and December 2017. Their conditions of pregnancy and reproductive outcome were analyzed. The clinical manifestations and ultrasonographic features were compared between these pregnant women and those with normal pregnancy.

Results

Of the 396 cases with follow-up data

118 cases (29.8%) wished to give a birth again and finally 96 cases (88.1%) were successfully pregnant

with a total of 104 pregnancies. Among them

62 pregnancies (59.6%) were intrauterine pregnancy while 26 pregnancies (25.0%) were RCSP. Although 278 cases (70.2%) had no pregnan

cy plans

there were 42 cases (16.9%) having subsequent pregnancies

with a total of 47 pregnancies. Among them

2 pregnancies (4.3%) were intrauterine pregnancy while 6 pregnancies (12.7%) were RCSP. In all pregnancies

the incidence of RCSP was 21.2% (32/151). Between the intrauterine pregnancy and RCSP groups

the latter group had older gestational age (

=0.020)

thinner remnant myometrial thickness of lower uterine segment of previous CSP (

=0.010) and larger times of abortion (

=0.029).

Conclusion

Women with CSP could be pregnant again after UACE combined with evacuation. It is apt to form RCSP in the subsequent pregnancy after the previous CSP. The gestational age and the remnant myometrial thickness of lower uterine segment of the previous CSP and the number of abortions are associated with RCSP.

关键词

Keywords

references

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