Influencing factors for contrast agent reflux in four-dimensional hysterosalpingo-contrast sonography: a logistic regression analysis

Rui WANG; Jinping WANG; Chaoxue ZHANG

doi:10.16016/j.1000-5404.201902157

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Influencing factors for contrast agent reflux in four-dimensional hysterosalpingo-contrast sonography: a logistic regression analysis

更新时间：2026-01-09

- Influencing factors for contrast agent reflux in four-dimensional hysterosalpingo-contrast sonography: a logistic regression analysis
- Journal of Third Military Medical University Vol. 41, Issue 15, Pages: 1473-1477(2019)
- 作者机构：
- 作者简介：
- 基金信息：
  
  the Project of Key Research and Opening Plan of Anhui Province in 2018(1804h08020248)
- DOI：10.16016/j.1000-5404.201902157
  CLC：
- Received：11 February 2019，
  
  Published：15 August 2019
- 稿件说明：
移动端阅览
Rui WANG, Jinping WANG, Chaoxue ZHANG. Influencing factors for contrast agent reflux in four-dimensional hysterosalpingo-contrast sonography: a logistic regression analysis[J]. Journal of Third Military Medical University, 2019, 41(15): 1473-1477.
DOI：

Rui WANG, Jinping WANG, Chaoxue ZHANG. Influencing factors for contrast agent reflux in four-dimensional hysterosalpingo-contrast sonography: a logistic regression analysis[J]. Journal of Third Military Medical University, 2019, 41(15): 1473-1477. DOI： 10.16016/j.1000-5404.201902157.

摘要

Abstract

Objective

To investigate the influencing factors of contract agent reflux during four-dimensional hysterosalpingo-contrast sonography.

Methods

A total of 235 infertility women (aged from 22 to 47 years

with an infertility duration of 1 to 13 years) who undertook four-dimensional hysterosalpingo-contrast sonography in the First Affiliated Hospital of Anhui University of Chinese Medicine from January 2017 to December 2018 were enrolled in this study. Retrospective analyses were conducted on the 101 patients who experienced reflux of contract agent during the examination. Ultrasonograms of their reflux were observed

and reasons for that were probed from the following 15 aspects: age

infertility time

tube patency

pain level

uterine position

endometrial thickness

menstruation examination time

infertility type

abortion history

uterine malformation

ectopic pregnancy history

gynecological inflammation

uterine space-occupying lesions

pelvic surgery history

and intrauterine adhesion.

Results

The incidence of contrast reflux was 42.9% in this cohort. Univariate analyses showed that endometrial thickness

history of abortion

menstruation examination time

intrauterine adhesion

type of infertility and tubal patency were associated with occurrence of contract reflux (

0.05). Multivariate logistic r

egression analyses indicated that endometrial thickness

menstruation examination time

type of infertility and tube patency were closely related with the reflux (

=0.036

0.045

0.025

0.004)

and endometrial thickness and menstruation examination time were negatively correlated with the reflux (

=-0.834

-0.802)

while type of infertility and obstruction of fallopian tubes were positively correlated (

=1.122

0.898).

Conclusion

Endometrial thickness < 6 mm

examination 3 to 4 d after menstruation

secondary infertility and tubal occlusion are the main causes of contrast reflux. Therefore

it is advisable to have the examination when the endometrial thickness is ≥6 mm and the menstruation is over for 5 to 7 d. Meanwhile

endometrial damage should be avoided and uterine cavity pressure be reduced as much as possible

which may be beneficial to keep incidence of reflux low.

关键词

Keywords

references

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