Relative factors to sarcopenia in type 2 diabetes patients

Cheng CHEN; Qiao ZHANG; Fang ZHONG

doi:10.16016/j.1000-5404.201902032

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Relative factors to sarcopenia in type 2 diabetes patients

更新时间：2026-01-09

- Relative factors to sarcopenia in type 2 diabetes patients
- Journal of Third Military Medical University Vol. 41, Issue 15, Pages: 1468-1472(2019)
- 作者机构：
- 作者简介：
- 基金信息：
  
  the Special Project for Outstanding Scientific and Technological Talents of Guizhou Province(黔省专合字[(2010)82号])
- DOI：10.16016/j.1000-5404.201902032
  CLC：
- Received：05 February 2019，
  
  Published：15 August 2019
- 稿件说明：
移动端阅览
Cheng CHEN, Qiao ZHANG, Fang ZHONG. Relative factors to sarcopenia in type 2 diabetes patients[J]. Journal of Third Military Medical University, 2019, 41(15): 1468-1472.
DOI：

Cheng CHEN, Qiao ZHANG, Fang ZHONG. Relative factors to sarcopenia in type 2 diabetes patients[J]. Journal of Third Military Medical University, 2019, 41(15): 1468-1472. DOI： 10.16016/j.1000-5404.201902032.

摘要

Abstract

Objective

To investigate the occurrence of sarcopenia in the patients with type 2 diabetes mellitus (T2DM) and the relationship of its related factors.

Methods

Cross-sectional survey was adopted to select 450 T2DM patients (256 males and 194 females) who were hospitalized in the Department of Endocrinology and Metabolism of Affiliated Hospital of Guizhou Medical University from April 2015 to November 2015. Their general conditions

blood indexes

and body composition indexes were investigated. According to the diagnostic criteria of the Asian Working Group on Sarcopenia

sarcopenia was diagnosed with relative skeletal muscle mass index (RASM) described as appendicular muscle mass divided by height square

with male

7.00 kg/m

and female

5.40 kg/m

Results

There were 64 patients suffering from sarcopenia

with a total prevalence rate of 14.22%. The prevalence rate of males and females was 19.14% and 7.73%

respectively (

0.05). The age was older and creatinine level was higher in the sarcopenia group than the non-sarcopenia group (

0.05). The body mass index (BMI)

android/gynoid (A/G) fat ratio and triglyceride level were significantly lower in the sarcopenia group compared with the non-sarcopenia group (

0.05). M

ultivariate logistic regression analysis showed that after correcting confounding factors including age and gender

smoking (

=2.156

95%

: 1.226~3.790) was a risk factor

while BMI (

=0.529

95%

: 0.448~0.625) and A/G fat ratio (

=0.007

95%

: 0.001~0.046) were protective factors for sarcopenia.

Conclusion

Smoking is a risk factor for sarcopenia in type 2 diabetic patients. BMI and A/G fat ratio may be protective factors for sarcopenia.

关键词

Keywords

references

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