Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study

Qiangqiang YANG; Tao DENG; Hong XU; Xue PENG; Xueli YANG; Guohua JIN; Xiaoyan ZHAO

doi:10.16016/j.1000-5404.201807219

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Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study

更新时间：2026-01-09

- Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study
- Journal of Third Military Medical University Vol. 40, Issue 21, Pages: 1973-1977(2018)
- 作者机构：
- 作者简介：
- 基金信息：
  
  the Special Project of Scientific Research for Public Welfare of National Health and Family Planning Commission(201502013)
- DOI：10.16016/j.1000-5404.201807219
  CLC：
- Received：31 July 2018，
  
  Published：15 November 2018
- 稿件说明：
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Qiangqiang YANG, Tao DENG, Hong XU, et al. Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study[J]. Journal of Third Military Medical University, 2018, 40(21): 1973-1977.
DOI：

Qiangqiang YANG, Tao DENG, Hong XU, et al. Clinical efficacy of 2 schedules of oral polyethylene glycol solution for bowel preparations before small bowel capsule endoscopy: a multicenter, randomized controlled study[J]. Journal of Third Military Medical University, 2018, 40(21): 1973-1977. DOI： 10.16016/j.1000-5404.201807219.

摘要

Abstract

Objective

To compare the intestinal preparation efficacy of taking 2 L polyethylene glycol (PEG) solution in 2 and 4 h before small bowel capsule endoscopy (SBCE) in order to explore the optimal time.

Methods

A multicenter

randomized controlled trial was conducted in 3 hospital during January 2016 and June 2018. According to our inclusion and exclusion criteria

totally 160 patients were enrolled

and then randomly assigned into 2 groups at a ratio of 1 :1 and given a schedule of oral administration of 2 L PEG in 4 or 6 h before SBCE

respectively. The main evaluation indexes were the excellent rate of small bowel visualization quality (SBVQ)

and the secondary ones included diagnostic yield

complete rate of total small intestine

gastric transit time

and small bowel transit time.

Results

The 4 h group obtained significantly higher excellent rate of SBVQ [(65.8±17.4)%

(59.3±17.3)%

=0.034

]

and shorter small bowel transit time (269.1±115.3

313.9±104.7 min

=0.019) when compared with the 6 h group. What's more

the diagnostic yield

complete rate of total small intestine and gastric transit time were 70.1% (54/77)

86.7%(66/77) and 38.0(19.0~89.5) min respectively in the 4 h group

and were 68.4%(54/79)

89.9%(71/79) and 28.5(11.7~50.5) min in the 6 h group

but there were no statistical differences between the 2 groups (

0.05).

Conclusion

The 2 schedules of taking 2 L PEG solution before SBCE have no significant effects on diagnostic yield

complete rate of total small intestine and gastric transit time

but the 4 h scheme presents better SBVQ.

关键词

Keywords

references

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