Value of Dixon magnetic resonance imaging sequence in diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis

Mingshan DU; Bing XIE; Xuanqi XIONG; Wenjing HOU; Wei CHEN

doi:10.16016/j.1000-5404.201807095

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Value of Dixon magnetic resonance imaging sequence in diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis

Clinical Medicine | 更新时间：2026-01-09

- Value of Dixon magnetic resonance imaging sequence in diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis
- Journal of Third Military Medical University Vol. 40, Issue 22, Pages: 2081-2086(2018)
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)第一附属医院放射科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201807095
  CLC： R445.2;R593.23;R684
- Received：12 July 2018，
  
  Revised：2018-09-21，
  
  Published：30 November 2018
- 稿件说明：
移动端阅览
Mingshan DU, Bing XIE, Xuanqi XIONG, et al. Value of Dixon magnetic resonance imaging sequence in diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis[J]. Journal of Third Military Medical University, 2018, 40(22): 2081-2086.
DOI：

Mingshan DU, Bing XIE, Xuanqi XIONG, et al. Value of Dixon magnetic resonance imaging sequence in diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis[J]. Journal of Third Military Medical University, 2018, 40(22): 2081-2086. DOI： 10.16016/j.1000-5404.201807095.

摘要

目的

探讨磁共振Dixon序列在评价强直性脊柱炎(ankylosing spondylitis

AS)患者骶髂关节骨髓水肿中的应用价值。

方法

收集本院2016年11月至2018年2月AS患者40例作为研究组，同期健康体检者20例作为对照组。AS患者入院后均行Bath强直性脊柱炎疾病活动度指数(Bath ankylosing spondylitis disease activity index，BASDAI)、Bath强直性脊柱炎功能指数(Bath ankylosing spondylitis functional index，BASFI)评分及C反应蛋白、血沉检查。研究组及对照组均行骶髂关节MRI常规序列及Dixon序列扫描，通过后处理工作站对各受检者Dixon序列图像进行分析，测量双侧骶髂关节面下Dixon序列水信号值。研究组双侧骶髂关节面下Dixon序列水信号值与BASDAI评分、BASFI评分、C反应蛋白、血沉及加拿大脊柱关节炎研究协会(spondyloarthritis research consortium Canada，SPARCC)骶髂关节评分进行相关性分析。

结果

研究组双侧骶髂关节面下Dixon序列水信号值均显著高于对照组(

0.05)；研究组双侧骶髂关节面下Dixon序列水信号值与BASDAI评分、BASFI评分、C反应蛋白、血沉及骶髂关节SPARCC评分均呈正相关关系(

0.05)。

结论

磁共振Dixon序列可以作为评价骶髂关节炎活动期的参考指标。

Abstract

Objective

To investigate the value of Dixon magnetic resonance imaging (MRI) sequence in the diagnosis of marrow edema of the sacroiliac joint in patients with ankylosing spondylitis (AS).

Methods

Forty patients with AS admitted in our hospital between November

2016 and February

2018 were selected as the case group and 20 healthy subjects recruited during the same time served as the control group. All the patients were assessed with Bath ankylosing spondylitis disease activity index (BASDAI) and Bath ankylosing spondylitis functional index (BASFI) and examined for C-reactive protein and erythrocyte sedimentation rate (ESR) after admission. The routine MRI sequence and Dixon sequence scan of the sacroiliac joint were performed in both groups. The Dixon sequence images of the subjects were analyzed using post-processing workstation

and the water signal intensity under the surface of the bilateral sacroiliac joints were measured and compared between the 2 groups. In the case group

the correlations were analyzed of water signal intensity of Dixon sequence under the bilateral sacroiliac joint with BASDAI

BASFI

C-reactive protein

ESR and sacroiliac joint SPARCC score.

Results

The water signal intensity under the bilateral sacroiliac joints on Dixon sequence images was significantly higher in the case group than in the healthy control group (

0.05). In the case group

water signal intensity under the bilateral sacroiliac joints was positively correlated with BASDAI

BASFI

C-reactive protein

ESR and the sacroiliac joint SPARCC score of the patients (

0.05).

Conclusion

Dixon MRI sequence can be used as an indicator for evaluating the active stage of sacroiliac arthritis in patients with AS.

关键词

Keywords

references

BRAUN J, SIEPER J. Ankylosing spondylitis[J]. Lancet, 2007, 369 (9570): 1379-1390. DOI: 10.1016/S0140-6736(07)60635-7.

SIEPER J, BRAUN J, DOUGADOS M, et al . Axial spondyloarthritis[J ] . Nat Rev Dis Primers, 2015, 1(5): 15013. DOI: 10.1038/nrdp.2015.13.

SLOBODIN G, ESHED I. Non-radiographic axial spondyloarthritis[J]. Isr Med Assoc J, 2015, 17(12): 770-776.

KLAUSER A, BOLLOW M, CALIN A, et al . Workshop report: clinical diagnosis and imaging of sacroiliitis, Innsbruck, Austria, October 9, 2003[J ] . J Rheumatol, 2004, 31(10): 2041-2047.

王东, 江华堂, 陈武标, 等. MRI与HLA-B27诊断强直性脊柱炎骶髂关节病变的联合应用[J].中国CT和MRI杂志, 2012, 10(6): 94-96. DOI: 10.3969/j.issn.1672-5131.2012.06.031.

WANG D, JIANG H T, CHEN W B, et al . The combination of MR imaging and HLAB 27 on the diagnosis of sacroiliac joints lesions in ankylosing spondylitis[J ] . Chin J CT MRI, 2012, 10(6): 94-96. DOI: 10.3969/j.issn.1672-5131.2012.06.031.

郭海燕, 詹浩辉, 李卫新.强直性脊柱炎早期骶髂关节炎的磁共振诊断价值[J].中国CT和MRI杂志, 2012, 10(2): 110-112. DOI: 10.3969/j.issn.1672-5131.2012.02.037.

GUO H Y, ZHAN H H, LI W X. Diagnostic value of MRI in the diagnosis of sacroilitis for early ankylosing spondylitis[J]. Chin J CT MRI, 2012, 10(2): 110-112. DOI: 10.3969/j.issn.1672-5131.2012.02.037.

徐铮, 李冠武, 顾昊, 等. 2点Dixon技术评价鼠骨质疏松模型骨髓脂肪:与病理对照[J].中国骨质疏松杂志, 2015, 21(4): 399-402. DOI: 10.3969/j.issn.1006-7108.2015.04.003.

XU Z, LI G W, GU H, et al . Evaluation of marrow adiposity using two-point Dixon method in a rat osteoporosis model:comparison with histopathology[J ] . Chin J Osteoporos, 2015, 21(4): 399-402. DOI: 10.3969/j.issn.1006-7108.2015.04.003.

陈瑶, 周蕾, 李冠武, 等. MRI水-脂成像评价原发性骨质疏松模型鼠骨髓脂肪含量的价值[J].临床放射学杂志, 2014, 33(10): 1604-1609. DOI:10.13437/j.cnki.jcr.2014.10.038.

CHEN Y, ZHOU L, LI G W, et al . Quantitative evaluation of marrow fat content in ovariectomized rats using MRI chemical shift-based water-fat separation imaging[J ] . J Clin Radiol, 2014, 33(10): 1604-1609. DOI:10.13437/j.cnki.jcr.2014.10.038.

FISHBEIN K W, MAKROGIANNIS S K, LUKAS V A, et al . Measurement of fat fraction in the human thymus by localized NMR and three-point Dixon MRI techniques[J ] . Magn Reson Imaging, 2018, 50: 110-118. DOI: 10.1016/j.mri.2018.03.016.

YOU J H, KIM I H, HWANG J, et al . Fracture of ankle: MRI using opposed-phase imaging obtained from turbo spin echo modified Dixon image shows improved sensitivity[J ] . Br J Radiol, 2018, 91(1088): 20170779. DOI: 10.1259/bjr.20170779.

ARNBAK B, LEBOEUF-YDE C, JENSEN T S. A systematic critical review on MRI in spondyloarthritis[J]. Arthritis Res Ther, 2012, 14(2): R55-R55. DOI: 10.1186/ar3768.

MADSEN OR. Stability of fatigue, pain, patient global assessment and the Bath Ankylosing Spondylitis Functional Index (BASFI) in spondyloarthropathy patients with stable disease according to the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)[J]. Rheumatol Int, 2018, 38(3): 425-432. DOI: 10.1007/s00296-017-3920-1.

杜旭娜, 李晏, 张胜利, 等.强直性脊柱炎病情活动度评分对强直性脊柱炎患者病情活动性判断的价值[J].中华内科杂志, 2012, 51(3): 206-209. DOI: 10.3760/cma.j.issn.0578-1426.2012.03.008.

DU X N, LI Y, ZHANG S L, et al . The value of ankylosing spondylitis disease activity score in evaluating disease activity of ankylosing spondylitis[J ] . Chin J Int Med, 2012, 51(3): 206-209. DOI: 10.3760/cma.j.issn.0578-1426.2012.03.008.

来东升.磁共振成像SPARCC评分在强直性脊柱炎中的临床应用[J].全科医学临床与教育, 2014, 12(3): 269-270, 279.

LAI D S. Clinical value of MRI SPARCC score in patients with ankylosing spondylitis[J]. Clin Educ Gen Pract, 2014, 12(3): 269-270, 279.

WEBER U, HODLER J, JURIK A G, et al . Assessment of active spinal inflammatory changes in patients with axial spondyloarthritis: validation of whole body MRI against conventional MRI[J ] . Anne Rheum Dis, 2010, 69(4): 648-653. DOI: 10.1136/ard.2009.108274.

GONG Y, ZHENG N, CHEN S B, et al . Ten years' experience with needle biopsy in the early diagnosis of sacroiliitis[J ] . Arthritis Rheum, 2012, 64(5): 1399-1406. DOI: 10.1002/art.33453.

VAN DEN BERG R, DE HOOGE M, BAKKER P A, et al . Metric properties of the SPARCC score of the sacroiliac joints—data from baseline, 3-month, and 12-month followup in the SPACE cohort[J ] . J Rheumatol, 2015, 42(7): 1186-1193. DOI: 10.3899/jrheum.140806.

BRAUN J, BARALIAKOS X, HERMANN K G A, et al . Extended report: Golimumab reduces spinal inflammation in ankylosing spondylitis: MRI results of the randomised, placebo- controlled GO-RAISE study[J ] . Ann Rheum Dis, 2012, 71(6): 878-884. DOI: 10.1136/annrheumdis-2011-200308.

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