Brain activation characteristics during mirror movements in healthy subjects: findings by functional near-infrared spectroscopy

Jingna ZHANG; Li WANG; Ye ZHANG; Kun YANG; Linqiong SANG; Pengyue LI; Minguo QIU

doi:10.16016/j.1000-5404.201804010

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Brain activation characteristics during mirror movements in healthy subjects: findings by functional near-infrared spectroscopy

Clinical Medicine | 更新时间：2026-01-09

- Brain activation characteristics during mirror movements in healthy subjects: findings by functional near-infrared spectroscopy
- Journal of Third Military Medical University Vol. 40, Issue 18, Pages: 1682-1687(2018)
- 作者机构：
  
  400038 重庆，陆军军医大学(第三军医大学)生物医学工程系医学图像学教研室
- 作者简介：
- 基金信息：
  
  the National Natural Science Foundation for Young Scholars of China(81601970);the Translational Medicine Cooperation Project of the First Hospital Affiliated of Third Military Medical University(SWH2014ZH03);the Young Scientists Development Program of Third Military Medical University(2016XPY05);the Young Scientists Development Program of Third Military Medical University(2017XQN04)
- DOI：10.16016/j.1000-5404.201804010
  CLC： R338.2;R446.9;R455
- Received：02 April 2018，
  
  Revised：2018-05-02，
  
  Published：30 September 2018
- 稿件说明：
移动端阅览
Jingna ZHANG, Li WANG, Ye ZHANG, et al. Brain activation characteristics during mirror movements in healthy subjects: findings by functional near-infrared spectroscopy[J]. Journal of Third Military Medical University, 2018, 40(18): 1682-1687.
DOI：

Jingna ZHANG, Li WANG, Ye ZHANG, et al. Brain activation characteristics during mirror movements in healthy subjects: findings by functional near-infrared spectroscopy[J]. Journal of Third Military Medical University, 2018, 40(18): 1682-1687. DOI： 10.16016/j.1000-5404.201804010.

摘要

目的

研究在镜像运动任务时大脑功能激活特征，为镜像运动疗法治疗截肢后幻肢痛提供脑功能影像学依据。

方法

招募13名健康被试，被试者均为本校的在校师生，采用功能性近红外光谱技术检测被试在左足运动执行和右足镜像运动时其大脑感觉运动皮层激活情况，以及大脑皮层含氧血红蛋白(HbO

)相对浓度变化时程特点。

结果

右足镜像运动与左足运动执行时，均显著激活双侧大脑主运动区和初级感觉皮层，其中激活最强的脑区在大脑右侧的初级感觉运动皮层(

0.05)。镜像任务HbO

相对浓度时间变化曲线出现下降趋势的时间早于运动执行，但两种任务HbO

浓度变化均值差异无统计学意义(

0.05)。

结论

功能近红外光谱技术研究结果证实了镜像运动和运动执行具有相似大脑激活模式和激活强度。

Abstract

Objective

To study the brain activation characteristics during mirror movements and provide functional near-infrared spectroscopy (fNIRS) evidence to support mirror therapy for phantom limb pain after amputation.

Methods

Thirteen healthy subjects (including 10 male and 3 female subjects

aged 22～34 years) were recruited in this study. fNIRS was used to measure brain activation and the changes in the relative concentration of oxygenated hemoglobin (HbO

) in the sensorimotor cortex during the execution of movements of the left foot and mirror movements of the right foot.

Results

Both of the two tasks activated the bilateral primary motor cortex and the primary sensory cortex

and the right primary sensorimotor cortex showed the strongest activation (

0.05). The mean HbO

concentration during the execution of the two tasks showed no significant difference

but a downward trend occurred in the time course of HbO

concentration changes in the mirror movements before the execution of movements (

0.05).

Conclusion

Our findings confirm that the brain activation patterns and intensity are similar during the execution of movements of the left foot and mirror movements of the right foot

which supports mirror therapy for treatment of phantom limb pain after amputation.

关键词

Keywords

references

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