Value of <sup>18</sup>F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis

Yuhan ZHANG; Shuhua RAN; Wei LUO; Yao WANG; Yang ZHANG

doi:10.16016/j.1000-5404.201803029

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Value of ¹⁸F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis

更新时间：2026-01-09

- Value of ¹⁸F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis
- Journal of Third Military Medical University Vol. 40, Issue 17, Pages: 1599-1604(2018)
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201803029
  CLC：
- Received：05 March 2018，
  
  Published：15 September 2018
- 稿件说明：
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Yuhan ZHANG, Shuhua RAN, Wei LUO, et al. Value of ¹⁸F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis[J]. Journal of Third Military Medical University, 2018, 40(17): 1599-1604.
DOI：

Yuhan ZHANG, Shuhua RAN, Wei LUO, et al. Value of ¹⁸F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis[J]. Journal of Third Military Medical University, 2018, 40(17): 1599-1604. DOI： 10.16016/j.1000-5404.201803029.

摘要

Abstract

Objective

To evaluate the value of

F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis by observing the findings in order to improve the diagnostic accuracy.

Methods

F-FDG PET/CT findings of 51 patients with pathologically diagnosed lymphomas or lymph node tuberculosis who had undergone the

F-FDG PET/CT scanning between September 2015 and September 2017 in our hospital were collected and retrospectively analyzed. The distribution

shape

size

and

F-FDG take-up were evaluated and analyzed.

Results

The 41 cases of lymphoma and 10 cases of lymph node tuberculosis presented as integration lesions (16 and 0 case)

calcified mediastinal lymph nodes (1 and 5 cases) and circular intake (1 and 0 case)

and combined with pulmonary tuberculosis (0 and 1 case). The diagnostic accuracy of

F-FDG PET and CT was 100% and 50% respectively.

F-FDG PET/CT findings for the 2 diseases were systemic ly

mph node enlargement (18 and 1 cases)

local lymph node enlargement (23 and 9 cases)

splenic involvement or higher

F-FDG take-up (14 and 2 cases)

bone involved or higher

F-FDG take-up (6 and 1 case)

both spleen and bone involved (4 and 0 case). For the lymphoma patients

the average size and average SUVmax value of lymph node was 30.42±14.03 mm and 13.40±7.56; while was 18.59±6.56 mm and 7.66±3.32 for lymph node tuberculosis patients. Significant difference were seen in the diameter and SUVmax value between the 2 groups of patients (

0.05). When the cutoff SUVmax value was 2.5

the sensitivity and specificity was 100% and 0%~10%

respectively in the diagnosis of lymphoma. According to the ROC curve

when the cutoff of SUVmax value was 9.725

the sensitivity and specificity was 65.9% and 80.0%

respectively.

Conclusion

There are similar findings in clinical manifestations and

F-FDG PET/CT images between lymphoma and lymph node tuberculosis

but the value of the examination is higher for diagnosis of the former

while lower for the latter. Increase of the cutoff SUVmax value and combination the size of lymph nodes can provide certain help to the differential diagnosis in a certain extent.

关键词

Keywords

references

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⁰

Value of 18F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis

DOI：10.16016/j.1000-5404.201803029

摘要

Abstract

关键词

Keywords

references

Value of ¹⁸F-FDG PET/CT in diagnosis of lymphoma and lymph node tuberculosis