Wenlian MA, Guihui TAO, Xiaoli YANG, et al. Correlation between salt taste threshold and severity of coronary heart disease[J]. Journal of Third Military Medical University, 2018, 40(11): 1044-1047.
DOI:
Wenlian MA, Guihui TAO, Xiaoli YANG, et al. Correlation between salt taste threshold and severity of coronary heart disease[J]. Journal of Third Military Medical University, 2018, 40(11): 1044-1047. DOI: 10.16016/j.1000-5404.201801156.
Correlation between salt taste threshold and severity of coronary heart disease
摘要
Abstract
Objective
2
To investigate the correlation between salt taste threshold and severity of coronary heart disease.
Methods
2
A cross-section study was performed on 198 patients with coronary heart disease diagnosed by coronary angiography admitted in the Third Affiliated Hospital of Army Medical University from October 2017 to January 2018. Another sex- and age-matched 193 patients without coronary artery stenosis by coronary angiography served as control group. According to the number of coronary lesion
the patients of the coronary heart disease group was further divided into single branch lesion
double branch lesion and triple branch lesion subgroups. And based on Gensini score
the severity of coronary lesion was evaluated. The patients' salt taste threshold was determined by using NaCl solution. The differences of salt taste threshold among the above groups were compared
and the correlation between salt taste threshold and severity of coronary heart disease was analyzed.
Results
2
The salt taste threshold was significantly higher in the coronary heart disease group than the control group [(0.75±0.21)%
vs
(0.59±0.18)%
P
<
0.05
]
. With the increase of diseased arteries
the threshold was elevated. After adjustment of traditional risk factors of coronary heart disease using logistic regression model
elevated salt taste threshold was found to increase the prevalence of coronary heart disease (
OR
=3.012
P
<
0.05). Salt taste threshold was positively correlated with the severity of coronary artery disease (Gensini score
r
=0.623
P
<
0.05).
Conclusion
2
Elevated salt taste threshold is a risk factor for coronary heart disease
and it is also positively correlated with the severity of the disease.
关键词
Keywords
references
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