Characteristics and research prospects of cerebral metabolism in patients with traumatic brain injury

Bo WEI; Zhaohui LI

doi:10.16016/j.1000-5404.201712050

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Characteristics and research prospects of cerebral metabolism in patients with traumatic brain injury

Expert Review | 更新时间：2026-01-09

- Characteristics and research prospects of cerebral metabolism in patients with traumatic brain injury
- Journal of Third Military Medical University Vol. 40, Issue 13, Pages: 1161-1165(2018)
- 作者机构：
  
  130031 长春，吉林大学中日联谊医院神经外科
- 作者简介：
- 基金信息：
  
  the Project of Youth Scientific Research Fund of Health and Family Planning Commission of Jilin Province(2015Q005)
- DOI：10.16016/j.1000-5404.201712050
  CLC： R364.2;R651.15
- Received：06 December 2017，
  
  Revised：2018-03-08，
  
  Published：15 July 2018
- 稿件说明：
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Bo WEI, Zhaohui LI. Characteristics and research prospects of cerebral metabolism in patients with traumatic brain injury[J]. Journal of Third Military Medical University, 2018, 40(13): 1161-1165.
DOI：

Bo WEI, Zhaohui LI. Characteristics and research prospects of cerebral metabolism in patients with traumatic brain injury[J]. Journal of Third Military Medical University, 2018, 40(13): 1161-1165. DOI： 10.16016/j.1000-5404.201712050.

摘要

Abstract

Cerebral metabolism failure is one of the most important pathophysiological changes after traumatic brain injury (TBI). The energy metabolism disorder following TBI is associated with failure to maintain normal ionic homeostasis

excitotoxic releases of glutamate and other excitatory neurotransmitters

free radicals damage

and mitochondrial dysfunction. There are several methods to measure cerebral metabolism

including jugular bulb catheter

cerebral microdialysis (CMD)

positron emission tomography (PET)

and magnetic resonance spectroscopy (MRS). It is of great importance to monitor cerebral metabolism in the TBI patients in order to evaluate the severity of brain injury

predict the risk for development of secondary cerebra injury

guide systemic glucose management

assess the ability of nerve repair

and so on. Monitoring cerebral metabolism has been an important part of multimodal monitoring in severe neurological patients.

关键词

Keywords

references

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