Correlation between early neurological deterioration and poor functional outcomes in patients with acute intracerebral hemorrhage

Xingchen WANG; Wensong YANG; Rui LI; Qi LI; Peng XIE

doi:10.16016/j.1000-5404.201711224

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Correlation between early neurological deterioration and poor functional outcomes in patients with acute intracerebral hemorrhage

更新时间：2026-01-09

- Correlation between early neurological deterioration and poor functional outcomes in patients with acute intracerebral hemorrhage
- Journal of Third Military Medical University Vol. 40, Issue 12, Pages: 1120-1124(2018)
- 作者机构：
  
  400016 重庆，重庆医科大学附属第一医院神经内科
- 作者简介：
- 基金信息：
  
  the National Natural Science Foundation for Young Scholars of China(81200899)
- DOI：10.16016/j.1000-5404.201711224
  CLC： R181.32; R741.04; R743.34
- Received：27 November 2017，
  
  Revised：2018-03-09，
  
  Published：2018-01
- 稿件说明：
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Xingchen WANG, Wensong YANG, Rui LI, et al. Correlation between early neurological deterioration and poor functional outcomes in patients with acute intracerebral hemorrhage[J]. Journal of Third Military Medical University, 2018, 40(12): 1120-1124.
DOI：

Xingchen WANG, Wensong YANG, Rui LI, et al. Correlation between early neurological deterioration and poor functional outcomes in patients with acute intracerebral hemorrhage[J]. Journal of Third Military Medical University, 2018, 40(12): 1120-1124. DOI： 10.16016/j.1000-5404.201711224.

摘要

目的

探讨急性脑出血发生早期神经功能恶化(early neurologic deterioration

END)与预后相关性。

方法

选取2016年1月-2017年3月神经内科收治的82例急性脑出血患者，按照其END发生情况分为END阳性组(16例)与END阴性组(66例)，比较两组患者临床资料及90 d功能预后情况，并运用单因素及多因素Logistic回归分析，总结END与不良功能预后发生的独立危险关系。

结果

END阳性组的不良远期预后发生率为87.5%，较阴性组(18.2%)差异有统计学意义(

0.05)。多因素Logistic回归分析结果显示，END发生(

=25.57

95%

：1.53~427.39，

=0.024)及入院随机血糖(

=2.11

95%

：1.13~3.91，

=0.018)是不良功能预后发生的独立危险因素。

结论

急性脑出血发生早期神经功能恶化会导致不良功能预后。

Abstract

Objective

To study the correlation between early neurological deterioration (END) and poor functional outcomes in patients with acute intracerebral hemorrhage.

Methods

Eighty-two patients with acute cerebral hemorrhage were admitted in our department between January

2016 and March

2017

including 16 with positive findings of END and 66 with negative findings of END. The clinical data and 90-day functional outcomes were compared between the 2 groups

and univariate and multivariate logistic regression analyses were used to assess the correlation between END and poor functional outcomes of the patients.

Results

The patients with END had a significantly higher incidence of poor functional outcome than the END-negative patients [87.5%(14/16)

18.2% (12/66)

0.05

]

. Multivariate logistic regression analysis showed that both END (

=25.57

95%

:1.53~427.39

=0.024)and random blood glucose level (

=2.11

95%

:1.13~3.91

=0.018)were independent risk factors of poor functional outcome in patients with acute intracerebral hemorrhage.

Conclusion

END is associated with poor functional outcomes in patients with acute intracerebral hemorrhage.

关键词

Keywords

references

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