Clinical value of intracranial pressure wave parameters in patients after intracranial aneurysm clipping

Hui LI; Zhijian HUANG; Hao WEN; Linjun QI; Guojing LIU; Weina CHAI; Dan XU; Xiaomin YANG; Xiaochuan SUN

doi:10.16016/j.1000-5404.201711139

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Clinical value of intracranial pressure wave parameters in patients after intracranial aneurysm clipping

Clinical Medicine | 更新时间：2026-01-09

- Clinical value of intracranial pressure wave parameters in patients after intracranial aneurysm clipping
- Journal of Third Military Medical University Vol. 40, Issue 7, Pages: 631-635(2018)
- 作者机构：
  
  1.400016 重庆，重庆医科大学附属第一医院神经外科
  2.400044 重庆，重庆大学物理学院
- 作者简介：
- 基金信息：
  
  the General Program of National Natural Science Foundation of China(81571159);the National Clinical Key-discipline Coustruction Program of China((2011)170)
- DOI：10.16016/j.1000-5404.201711139
  CLC： R181.32;R741.044;R743.9
- Received：17 November 2017，
  
  Revised：2018-01-07，
  
  Published：15 April 2018
- 稿件说明：
移动端阅览
Hui LI, Zhijian HUANG, Hao WEN, et al. Clinical value of intracranial pressure wave parameters in patients after intracranial aneurysm clipping[J]. Journal of Third Military Medical University, 2018, 40(7): 631-635.
DOI：

Hui LI, Zhijian HUANG, Hao WEN, et al. Clinical value of intracranial pressure wave parameters in patients after intracranial aneurysm clipping[J]. Journal of Third Military Medical University, 2018, 40(7): 631-635. DOI： 10.16016/j.1000-5404.201711139.

摘要

目的

分析颅内压波形参数与患者术后早期临床表现的相关性，探讨颅内动脉瘤夹闭术后颅内压波形参数的临床价值。

方法

收集2016年11月至2017年7月重庆医科大学附属第一医院神经外科重症监护室颅内动脉瘤夹闭术后使用颅内压(intracranial pressure，ICP)监测的55例患者的临床资料。根据患者ICP植入术后24 h内的ICP数据，使用领域平均振幅算法计算2个ICP波形参数：平均ICP值(mean intracranial pressure，MICP)和平均ICP振幅值(mean intracranial pressure wave amplitude，MWA)。分析MICP、MWA与患者术前病情及术后早期临床表现的关系。

结果

① 患者术前病情较轻者，其术后MICP、MWA越低。②根据术后格拉斯哥评分(glasgow coma score，GCS)将患者分为3组(GCS 3~8分，GCS 9~12分，GCS 13~15分)，各组间MICP和MWA差异均有统计学意义(

0.05)。③术后GCS评分与MICP(

=-0.619，

0.05)、MWA(

=-0.782，

0.05)呈负相关，且MWA与GCS评分相关性更强。

结论

ICP波形参数MICP、MWA能有效地反映颅内动脉瘤夹闭术后早期患者的神经功能障碍。

Abstract

Objective

To analyze the correlation between the parameters of intracranial pressure wave and early clinical manifestations in the patients after intracranial aneurysm clipping

and investigate the clinical value of these parameters.

Methods

Clinical data of 55 patients with full data on intracranial pressure (ICP) after intracranial aneurysm clipping in our neurosurgical department from November 2016 to July 2017 were collected in this study. According to the ICP results within 24 h after implantation

2 ICP parameters

mean intracranial pressure (MICP) and mean intracranial pressure wave amplitude (MWA) were calculated by area average amplitude algorithm. The correlations of MICP and MWA with the preoperative conditions and postoperative clinical manifestations were analyzed.

Results

① For the patients with milder preoperative conditions

they had lower MICP and MWA after operation. ②When the patients were divided into 3 groups based on Glasgow coma score (GCS

3~8

9~12 and 13~15 points respectively)

significant differences were seen in MWA and MICP among different GCS groups (

0.05). ③There were negative correlation of postoperative GCS score with MICP (

=-0.619

0.05) and MWA (

=-0.782

0.05)

with MWA more significant.

Conclusion

ICP wave parameters

MWA and MICP

both can effectively indicate early nervous dysfunction in patients after intracranial aneurysm clipping.

关键词

Keywords

references

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