Efficacy of standardized cancer pain treatment for improving quality of life in patients with severe cancer pain

Hong LIU; Yuanjing JIANG; Shuixia LIU

doi:10.16016/j.1000-5404.201711131

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Efficacy of standardized cancer pain treatment for improving quality of life in patients with severe cancer pain

Clinical Medicine | 更新时间：2026-01-09

- Efficacy of standardized cancer pain treatment for improving quality of life in patients with severe cancer pain
- Journal of Third Military Medical University Vol. 40, Issue 10, Pages: 934-938(2018)
- 作者机构：
  
  400042 重庆，陆军军医大学(第三军医大学)第三附属医院(野战外科研究所)肿瘤中心
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201711131
  CLC： R181.32; R441.1; R473.73
- Received：16 November 2017，
  
  Revised：2018-03-19，
  
  Published：30 May 2018
- 稿件说明：
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Hong LIU, Yuanjing JIANG, Shuixia LIU. Efficacy of standardized cancer pain treatment for improving quality of life in patients with severe cancer pain[J]. Journal of Third Military Medical University, 2018, 40(10): 934-938.
DOI：

Hong LIU, Yuanjing JIANG, Shuixia LIU. Efficacy of standardized cancer pain treatment for improving quality of life in patients with severe cancer pain[J]. Journal of Third Military Medical University, 2018, 40(10): 934-938. DOI： 10.16016/j.1000-5404.201711131.

摘要

目的

探讨癌痛规范化治疗对中重度癌痛患者生活质量及临床效果的影响分析。

方法

采用患者自身前后对照、前瞻性研究方法，以2016年1月至2017年6月陆军军医大学第三附属医院(野战外科研究所)肿瘤中心收治的晚期癌症并伴有中重度癌痛的110例患者为研究对象，实施以疼痛的“常规、量化、全面、动态”评估、规范化综合治疗、不良反应防治、健康教育和随访为护理要点的癌痛规范化治疗，以数字疼痛分级法(numerical rating scale

NRS)、生活质量评分(quality of life

QOL)和体能状况Karn of sky评分法(KPS)、不良反应发生率作为评价指标，比较分析患者实施癌痛规范化治疗前后生活质量的变化。

结果

中重度癌痛患者在实施规范化治疗后，92.7%患者的疼痛强度降低至轻度疼痛或无痛；不良反应(便秘、头晕、恶心呕吐、嗜睡和尿潴留)发生率明显降低(

0.05)；生活质量评分的12项内容均明显改善，平均QOL评分和KPS评分分别为49.91±7.64和84.51±3.56，显著高于规范化治疗前的29.40±10.38和68.42±9.23，差异有统计学意义(

0.05)。

结论

实施癌痛规范化治疗能有效缓解晚期癌症患者的疼痛，降低药物的不良反应发生率，改善体能状态，提高生活质量。

Abstract

Objective

To evaluate the effect of standardized cancer pain treatment for improving the quality of life (QOL) in the patients with severe cancer pain.

Methods

This prospective

self-controlled study was conducted among 110 terminal cancer patients with severe pain hospitalized in our center between January

2016 and June

2017. The patients received standardized pain management with routine

quantitative

comprehensive and dynamic pain assessment

standardized comprehensive treatment

adverse effect control

health education and follow-up. The changes in the patients' QOL after the implementation of standardized treatment were assessed in terms of changes in numerical rating scale (NRS) scores

QOL scores

Karn of sky performance status (KPS) and the incidence of adverse reactions.

Results

After the implementation of the standardized pain management

92.7% of the patients with moderate or severe cancer pain reported obviously reduced pain intensity to mild pain or total pain relief with also significantly reduced

incidences of adverse reactions (constipation

dizziness

nausea

vomiting

drowsiness and urinary retention) (

0.05). The standardized pain management achieved significant improvements in the scores of the 12 quality of life items

and significantly reduced the average QOL score (from 49.91±7.64 to 29.40±10.38) and KPS score (from 84.51±3.56 to 68.42±9.23) of the patients (

0.05).

Conclusion

The standardized cancer pain treatment can effectively reduce the pain level

reduce the incidence of adverse reactions

and improve the physical condition and quality of life of patients with terminal cancer.

关键词

Keywords

references

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