Clinical significance of T-SPOT.TB for diagnosis and treatment of tuberculosis in panniculitis patients

Ran HU; Ping WANG; Qiquan CHEN; Baiyu ZHONG; Zhiqiang SONG; Fei HAO

doi:10.16016/j.1000-5404.201710182

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Clinical significance of T-SPOT.TB for diagnosis and treatment of tuberculosis in panniculitis patients

Clinical Medicine | 更新时间：2026-01-09

- Clinical significance of T-SPOT.TB for diagnosis and treatment of tuberculosis in panniculitis patients
- Journal of Third Military Medical University Vol. 40, Issue 6, Pages: 528-531(2018)
- 作者机构：
  
  400038 重庆, 陆军军医大学(第三军医大学)第一附属医院皮肤科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201710182
  CLC： R378.911;R446.5;R758.69
- Received：25 October 2017，
  
  Revised：2017-11-27，
  
  Published：30 March 2018
- 稿件说明：
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Ran HU, Ping WANG, Qiquan CHEN, et al. Clinical significance of T-SPOT.TB for diagnosis and treatment of tuberculosis in panniculitis patients[J]. Journal of Third Military Medical University, 2018, 40(6): 528-531.
DOI：

Ran HU, Ping WANG, Qiquan CHEN, et al. Clinical significance of T-SPOT.TB for diagnosis and treatment of tuberculosis in panniculitis patients[J]. Journal of Third Military Medical University, 2018, 40(6): 528-531. DOI： 10.16016/j.1000-5404.201710182.

摘要

目的

探索结核感染T细胞斑点试验(T-SPOT.TB)检测用于脂膜炎患者中结核感染病因分析的价值。

方法

回顾性分析2011-2013年我院159例病理诊断为脂膜炎并进行T-SPOT.TB检测的患者的临床及组织病理资料，并对其中的92名患者进行3年的随访，31名健康人作研究对照。

结果

脂膜炎中T-SPOT.TB检查阳性率为76.1%，显著高于正常人群(9.7%，

＜0.001)；抗结核治疗患者有效率为75.3%，复发率为20.0%，其中完成6个月疗程的患者复发率显著低于3个月内停药的患者(

＜0.05)。

结论

T-SPOT.TB检测对于查找结核感染相关的脂膜炎患者有一定的价值。

Abstract

Objective

To explore the significance of T-SPOT.TB assay in the etiological analysis for panniculitis patients.

Methods

We retrospectively reviewed the clinical and histopathological features of 159 cases of panniculitis diagnosed in our hospital who underwent T-SPOT.TB assay from January 2011 to December 2013. And 92 cases of them were followed up by telephone for 3 years. Another 31 health individuals served as normal control.

Results

The overall positive rate to T-SPOT.TB assay was 76.1% in the panniculitis patients

significantly higher than that of healthy subjects (9.7%

＜0.001). The overall effective rate was 75.3% for anti-tuberculosis treatment

and the recurrence rate was 20.0%. The patients who accomplished treatment course of 6 months had obviously lower recurrent rate than those who only have in 3 months' treatment (

＜0.05).

Conclusion

T-SPOT.TB assay is valuable to detect the tuberculosis infection in panniculitis patients.

关键词

Keywords

references

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