Detection rate and risk factors of colorectal polyps in asymptomatic individuals

Yanli WANG; Wei LEI; Yujun KANG; Feng JIANG; Mengjun REN; Hongyu CUI

doi:10.16016/j.1000-5404.201707133

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Detection rate and risk factors of colorectal polyps in asymptomatic individuals

Clinical Medicine | 更新时间：2026-01-09

- Detection rate and risk factors of colorectal polyps in asymptomatic individuals
- Journal of Third Military Medical University Vol. 39, Issue 22, Pages: 2232-2237(2017)
- 作者机构：
  
  400014 重庆，重庆市人民医院消化内科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201707133
  CLC： R181.32;R574.63;R735.35
- Received：20 July 2017，
  
  Revised：2017-09-20，
  
  Published：30 November 2017
- 稿件说明：
移动端阅览
Yanli WANG, Wei LEI, Yujun KANG, et al. Detection rate and risk factors of colorectal polyps in asymptomatic individuals[J]. Journal of Third Military Medical University, 2017, 39(22): 2232-2237.
DOI：

Yanli WANG, Wei LEI, Yujun KANG, et al. Detection rate and risk factors of colorectal polyps in asymptomatic individuals[J]. Journal of Third Military Medical University, 2017, 39(22): 2232-2237. DOI： 10.16016/j.1000-5404.201707133.

摘要

目的

探讨不同病理类型结直肠息肉在无症状人群中的检出情况及相关危险因素。

方法

收集我院2013-2016年接受结直肠镜检查但无临床症状的体检者702例的临床资料和肠镜结果。根据肠镜结果和息肉病理类型分组，分析不同病理类型息肉的检出情况及危险因素。

结果

腺瘤、增生性息肉(hyperplasic polyp

HP)、广基锯齿状腺瘤/息肉、传统锯齿状腺瘤、炎性息肉的检出率分别为14.0%(98/702)、8.8%(62/702)、0.6%(4/702)、0.1%(1/702)、0.9%(6/702)，进展期腺瘤的检出率为2.7%(19/702)。年龄≥50岁(50~

60岁:

=1.712

95%

=1.048~2.798

=0.032；≥60岁:

=2.151

95%

=1.146~4.036

=0.017)、吸烟≥400支/年(

=1.866

95%

=1.120~3.109

=0.017)、一级亲属结直肠癌家族史(

=1.853

95%

=1.038~3.310

=0.037)是腺瘤的独立危险因素；BMI≥24.0 kg/m

(

=3.1

95%

=1.069~9.280

=0.037)、2型糖尿病(

=4.430

95%

=1.248~15.721

=0.021)是进展期腺瘤的独立危险因素；吸烟≥400支/年(

=2.200

95%

=1.203~4.024

=0.010)是HP唯一的独立危险因素。

结论

腺瘤及HP是无症状人群结直肠息肉的主要病理类型。吸烟、50岁以上、一级亲属结直肠癌家族史是腺瘤的危险因素，若同时合并2型糖尿病或体质量超重则增加进展期腺瘤的风险。吸烟也是HP的危险因素，且对HP的促进作用可能更显著。

Abstract

Objective

To investigate the detection rate and risk factors of colorectal polyps of different histological types in asymptomatic individuals.

Methods

From January 2013 to December 2016

a total of 702 individuals without clinical symptoms underwent colonoscopy in our hospital. The clinical data and results of colonoscopy were obtained from each subject. The detection rate and risk factors of colorectal polyps of different histological types were analyzed in the subjects with different colonoscopic and histopathological findings.

Results

Among the 702 individuals

the detection rates of adenoma

hyperplasic polyp

sessile serrated adenoma/polyp

traditional serrated adenoma and inflammatory polyp were 14.0% (98/702)

8.8% (62/702)

0.6% (4/702)

0.1% (1/702) and 0.9% (6/702)

respectively; the detection rate of advanced adenoma was 2.7% (19/702). An age over 50 years (50-

60 years:

=1.712

95%

=1.048-2.798

=0.032; over 60 years:

=2.151

95%

=1.146-4.036

=0.017)

smoking more than 20 pack-year (

=1.866

95%

=1.120-3.109

=0.017)

and first-degree family history of colorectal cancer (

=1.853

95%

=1.038-3.310

=0.037) were identified as the independent risk factors of adenoma. A BMI over 24.0 kg/m

(

=3.150

95%

=1.069-9.280

=0.037) and type 2 diabetes (

=4.430

95%

=1.248~15.721

=0.021) were independently correlated with advanced adenoma. Smoking more than 20 pack-year (

=2.200

95%

=1.203-4.024

=0.010) was found to be the only independent risk factor of hyperplasic polyp.

Conclusion

Adenoma and hyperplasic polyp are the main histological types of colorectal polyps in asymptomatic individuals. Smoking

age over 50 years and first-degree family history of colorectal cancer are all risk factors of adenoma

and concurrent type 2 diabetes or overweight are associated with an increased risk of advanced adenoma. Smoking is an independent risk factor of hyperplasic polyp and adenomas

and may produce a stronger influence than adenoma on the development of hyperplasic polyp.

关键词

Keywords

references

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