Retrospective analysis of HBV and HCV infection in HIV/AIDS patients in Chongqing

Huan NIE; Wenxiu XIAO; Deyi TANG; Chengyu HUANG

doi:10.16016/j.1000-5404.201705085

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Retrospective analysis of HBV and HCV infection in HIV/AIDS patients in Chongqing

Clinical Medicine | 更新时间：2026-01-09

- Retrospective analysis of HBV and HCV infection in HIV/AIDS patients in Chongqing
- Journal of Third Military Medical University Vol. 39, Issue 21, Pages: 2140-2144(2017)
- 作者机构：
  
  1.400038 重庆，重庆市公共卫生医疗救治中心：预防保健科
  2.400038 重庆，重庆市公共卫生医疗救治中心：感染门诊
  3.400038 重庆，重庆市公共卫生医疗救治中心：医院感染控制科3
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201705085
  CLC： R195.4;R373.21;R512.91
- Received：23 May 2017，
  
  Revised：2017-07-05，
  
  Published：15 November 2017
- 稿件说明：
移动端阅览
Huan NIE, Wenxiu XIAO, Deyi TANG, et al. Retrospective analysis of HBV and HCV infection in HIV/AIDS patients in Chongqing[J]. Journal of Third Military Medical University, 2017, 39(21): 2140-2144.
DOI：

Huan NIE, Wenxiu XIAO, Deyi TANG, et al. Retrospective analysis of HBV and HCV infection in HIV/AIDS patients in Chongqing[J]. Journal of Third Military Medical University, 2017, 39(21): 2140-2144. DOI： 10.16016/j.1000-5404.201705085.

摘要

目的

分析重庆市艾滋病病毒感染者(HIV)和获得性免疫缺陷综合征(acquired immune deficiency syndrome，AIDS)患者(简称HIV/AIDS患者)合并感染乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)状况。

方法

利用《艾滋病综合防治系统——抗病毒治疗管理》数据库，回顾收集重庆市2004-2015年HIV/AIDS治疗患者基本情况和HBsAg、Anti-HCV实验室检测结果，利用SPSS 19.0统计软件进行统计分析。

结果

截至2015年12月31日，重庆市HIV/AIDS患者中HBsAg和(或)Anti-HCV总检测率55.1%(11 231/20 397)，其中HBsAg和Anti-HCV都进行检测的患者有9 307例。HIV/HBV、HIV/HBV/HCV、HIV/HCV合并感染的比例分别为9.8%、0.9%、4.5%。HIV/HCV合并感染在30~45岁年龄段构成比最高；HIV/HBV合并感染在男性中构成比最高，与HIV单纯感染组比较，差异均具有统计学意义(

0.05)。HIV/HBV合并感染及HIV单纯感染均在性传播中构成比最高，差异无统计学意义(

=0.177)；HIV/HCV和HIV/HBV/HCV合并感染在静脉吸毒中构成比最高，与HIV单纯感染比较，差异具有统计学意义(

0.05)。主城9区中HIV/AIDS患者及合并感染患者比例最高。合并感染组病死率均高于HIV单纯感染组，HIV/HBV/HCV组病死率最高。

结论

重庆市HIV/AIDS患者中HBsAg、Anti-HCV检测率较低，不同感染模式具有不同的流行病学特征，且合并感染的病死率较高，需要进一步加强对重庆市HIV/AIDS患者中HBV、HCV合并感染检测率和治疗情况的管理。

Abstract

Objective

To review and analyze the epidemiology of HIV/AIDS co-infected with HBV and/or HCV in Chongqing.

Methods

By using the AIDS Integrated Control System-anti-virus Treatment Management Database

the general data of HIV/AIDS patients and their results of HBsAg/anti-HCV laboratory test from 2004 to 2015 in Chongqing were collected. The co-infection of HBV and/or HCV with HIV was analyzed statistically with SPSS 19.0.

Results

Until December 31

2015

the total detection rate of HBsAg and/or Anti-HCV in HIV/AIDS patients in Chongqing was 55.1% (11 231/20 397). Among them

9 307 patients were detected for both HBsAg and anti-HCV tests. The infectious rates of HIV/HBV

HIV/HBV/HCV and HIV/HCV were 9.8%

0.9% and 4.5%

respectively. Compared with the HIV-infected group

HIV/AIDS patients were more prone to have HCV infection at the 30 to 45 years old group

and the male HIV/AIDS patients were more common to have HBV infection than the HIV group (

0.05). HIV/HBV co-infection and HIV infection are mainly sexually transmitted

though without significant difference (

=0.177)

and intravenous drug use was the main way to cause HCV infection when compared with the only HIV patients (

0.05). The fatality rate of the co-infected groups were higher than that of the HIV infection group and HIV/HBV/HCV group had the highest fatality rate.

Conclusions

The detection rate of HBsAg and anti-HCV in HIV/AIDS patients in Chongqing is relatively low

and the different infection patterns have different epidemiological characteristics. More efforts should be made to improve the detection rate and treatment of HIV/AIDS patients co-infected with HBV and/or HCV in Chongqing.

关键词

Keywords

references

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