Health-related quality of life among servicemen stationed at plateau by EQ-5D and its correlation analysis with chronic mountain sickness

Linlin ZHOU; Chun LIU; Yu CHEN; Mingchun CAI; Qingyuan HUANG; Yuqi GAO

doi:10.16016/j.1000-5404.201704015

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Health-related quality of life among servicemen stationed at plateau by EQ-5D and its correlation analysis with chronic mountain sickness

Military Medicine | 更新时间：2026-01-09

- Health-related quality of life among servicemen stationed at plateau by EQ-5D and its correlation analysis with chronic mountain sickness
- Journal of Third Military Medical University Vol. 39, Issue 13, Pages: 1410-1414(2017)
- 作者机构：
  
  1.400038 重庆第三军医大学卫勤训练基地，卫生勤务学教研室
  2.400038 重庆，第三军医大学高原军事医学系，教育部高原环境医学重点实验室，全军高原生理与高原病研究重点实验室，高原特需药品与卫生装备研究室
- 作者简介：
- 基金信息：
  
  the Major Project of PLA "Twelfth Five-year Plan"(AWS14C007);the Key Project of PLA "Twelfth Five-year Plan"(EWS11J042);the National Training Fund for Basic Science Talents(J1310001)
- DOI：10.16016/j.1000-5404.201704015
  CLC： R195;R594.3;R821.2
- Received：05 April 2017，
  
  Revised：2017-05-06，
  
  Published：15 July 2017
- 稿件说明：
移动端阅览
Linlin ZHOU, Chun LIU, Yu CHEN, et al. Health-related quality of life among servicemen stationed at plateau by EQ-5D and its correlation analysis with chronic mountain sickness[J]. Journal of Third Military Medical University, 2017, 39(13): 1410-1414.
DOI：

Linlin ZHOU, Chun LIU, Yu CHEN, et al. Health-related quality of life among servicemen stationed at plateau by EQ-5D and its correlation analysis with chronic mountain sickness[J]. Journal of Third Military Medical University, 2017, 39(13): 1410-1414. DOI： 10.16016/j.1000-5404.201704015.

摘要

目的

了解常驻高原部队官兵健康相关生命质量情况，探讨其与慢性高原病之间的关系。

方法

分层随机抽取某军区驻高原部队956个样本及该军区驻平原587个对照样本，实施欧洲五维健康量表(Europe health-related quality of life questio

nnaire 5 dimensions，EQ-5D)和慢性高原病(Chronic mountain sickness

CMS)检查。采用

检验、卡方检验、线性相关、非参数检验、方差分析等统计方法进行分析。

结果

高原组行动能力、疼痛或不舒服、焦虑或沮丧各维度评分均显著高于对照组(

＜0.05)，EQ直观模拟标度尺(EQ visual analogue scale，EQ-VAS)评分显著低于对照组(

＜0.05)。行动能力、自我照顾、疼痛或不舒服、焦虑或沮丧各维度与CMS呈显著正相关(

＜0.05)，EQ-VAS评分与CMS呈显著负相关(

＜0.05)；疼痛或不舒服与心率和血红蛋白浓度呈显著正相关(

＜0.05)，EQ-VAS评分与心率呈显著负相关(

＜0.05)。高原组中健康组、轻度CMS组、中重度CMS组各维度和EQ-VAS评分差异显著(

＜0.05)。

结论

常驻高原官兵的健康相关生命质量与CMS的发生有显著相关性。EQ-5D可以对高原官兵，尤其是CMS官兵的健康状况进行全面的评估，为高原卫勤保障措施的制定提供科学依据。

Abstract

Objective

To investigate the status of health-related quality of life in officers and soldiers stationed at high altitude

and explore its relationship with chronic mountain sickness (CMS).

Methods

Atotal of 956 subjects and 587 controls were sampled from the troops stationed at plateau and flatland respectively inamilitary command by stratified random sampling. Europe health-related quality of life questionnaire 5 dimensions (EQ-5D) and CMS diagnoses were performed on them. Student's

test

Chi

-square

Correlation test

Nonparametric analysis

and ANOVA were used for analysis.

Results

The scores of mobility

pain/discomfort and anxiety/dispersion were significantly higher (

0.05)

and the scores of EQ visual analogue scale (EQ-VAS) were significantly lower (

0.05) in the high altitude group than the control. The dimensions of mobility

self-care

pain/discomfort and anxiety/dispersion were positively correlated with CMS (

0.05). The scores of EQ-VAS were negatively correlated with CMS (

0.05). Pain/discomfort had positive correlation with heart rate and hemoglo

bin concentration (

0.05). The scores of EQ-VAS had negative correlation with heart rate (

0.05). There were significant differences in different dimensions and EQ-VAS score among those health

with mild and moderate-severe CMS from the high altitude group (

0.05).

Conclusion

Health-related quality of life is significant correlated with the occurrence of CMS in the officers and soldiers stationed in high altitude. EQ-5D can offeracomprehensive evaluation to the health state of the soldiers

especially those with CMS

and provide scientific evidences for the establishment of altitude medical service measures.

关键词

Keywords

references

高钰琪.高原病理生理学[M].北京:人民卫生出版社, 2006.

GAO Y Q. High altitude physiopathology[M]. Beijing: People's Medical Publishing House, 2006.

LI X, PEI T, XU H, et al . Ecological Study of Community-LevelFactorsAssociatedWithChronicMountainSickness in the YoungMaleChineseImmigrantPopulation in Tibet[J ] . Journal of Epidemiology, 2012, 22(2): 136-143. DOI:10.2188/jea.je20110058.

PEI T, LI X, TAO F, et al . Burden of disease resulting from chronic mountain sickness among young Chinese male immigrants in Tibet[J ] . BMC Public Health, 2012, 12: 401. DOI:10.1186/1471-2458-12-401.

赵久兴.高原地区使用富氧装置及不同给氧方法对血红蛋白的影响[J].高原医学杂志, 2009, 19(2): 44-45. DOI:10.3969/j.issn.1007-3809.2009.02.016.

ZHAO J X. The effect on hemogloin of residents in highland after application of oxygen-rich devices[J]. J High Alti Med, 2009, 19(2): 44-45. DOI:10.3969/j.issn.1007-3809.2009.02.016.

LEóN-VELARDE F, MAGGIORINI M, REEVES JT, et al . Consensus statement on chronic and subacute high altitude diseases[J ] . High Alt Med Biol, 2005, 6(2): 147-157. DOI:10.1089/ham.2005.6.147.

TAN Z, LIANG Y, LIU S, et al . Health-relatedquality of life as measured with EQ-5D among populations with and without specificchronicconditions: apopulation-basedsurvey in Shaanxi Province, China[J ] . PLoS ONE, 2013, 8(7): e65958. DOI:10.1371/journal.pone.0065958.

CRAIG B M, PICKARD A S, LUBETKIN E I. Health problems are more common, but less severe when measured using newer EQ-5D versions[J]. J Clin Epidemiol, 2014, 67(1): 93-99. DOI:10.1016/j.jclinepi.2013.07.011.

WANG Y, TAN N C, TAY E G, et al . Cross-cultural measurement equivalence of the 5-level EQ-5D (EQ-5D-5L) in patients with type 2 diabetes mellitus in Singapore[J ] . Health and Quality of Life Outcomes, 2015, 13(1). DOI:10.1186/s12955-015-0297-2.

MAHESWARAN H, PETROU S, REES K, et al . Estimating EQ-5D utility values for major health behavioural risk factors in England[J ] . JEpidemiol Community Health, 2013, 67(2): 172-180. DOI:10.1136/jech-2012-201019.

KIM S K, KIM S H, Jo M W, et al . Estimation of minimally important differences in the EQ-5D and SF-6D indices and their utility in stroke[J ] . Health Qual Life Outcomes, 2015, 13: 32. DOI:10.1186/s12955-015-0227-3.

HONG J Y, LEE S A, KIM S Y, et al . Factors associated with quality of life measured by EQ-5D in patients with nontuberculous mycobacterial pulmonary disease[J ] . Quality of Life Research, 2014, 23(10): 2735-2741. DOI:10.1007/s11136-014-0727-3.

MULHERN B, O'GORMAN H, ROTHERHAM N, et al . Comparing the measurement equivalence of EQ-5D-5L across different modes of administration[J ] . Health Qual Life Outcomes, 2015, 13: 191. DOI:10.1186/s12955-015-0382-6.

CHANG T J, TARN Y H, HSIEH C L, et al . Taiwanese version of the EQ-5D: validation in a representative sample of the Taiwanese population[J ] . Taiwanyizhi, 2007, 106(12): 1023-1031. DOI:10.1016/S0929-6646(08)60078-9.

邢亚彬, 马爱霞.欧洲五维健康量表EQ-5D-5L中文版的信效度研究[J].上海医药, 2013, 34(9): 40-43.

XING Y B, MA A X. Study on reliability and validity of chinese version of eq-5d-5l[J]. Shanghai Med Pharm J, 2013, 34(9): 40-43.

李明晖, 罗南.欧洲五维健康量表(EQ-5D)中文版应用介绍[J].中国药物经济学, 2009(1): 49-57. DOI:10.3969/j.issn.1673-5846.2009.01.007.

LI M H, LUO N. The Chinese version of European quality of life 5-dimensions[J]. Chin J Pharm Economics, 2009(1): 49-57. DOI:10.3969/j.issn.1673-5846.2009.01.007.

GAO F, NG G Y, CHEUNG Y B, et al . The Singaporean English and Chinese versions of the EQ-5D achieved measurement equivalence in cancer patients[J ] . J Clin Epidemiol, 2009, 62(2): 206-213.DOI:10.1016/j.jclinepi.2008.03.007.

蔡鹏, 张瑶, 刘丽军, 等.慢性高原病的遗传基础[J].国外医学(医学地理分册), 2016, 37(2): 182-185. DOI:10.3969/j.issn.1001-8883.2016.02.025.

CAI P, ZHANG Y, LIU L J, et al . Heredity basis of chronic altitude sickness[J ] . Foreign Med Sci (Section of Medgeography), 201 6, 37(2): 182-185. DOI:10.3969/j.issn.1001-8883.2016.02.025.

周琳琳, 刘春, 陈郁, 等.高原驻防部队官兵焦虑、抑郁情况调查及其与慢性高原病的相关性分析[J].解放军医学杂志, 2014, 39(7): 576-580. DOI:10.11855/j.issn.0577-7402.2014.07.13.

ZHOU L L, LIU C, CHEN Y, et al . A survey of anxiety and depression in servicemen stationed at high altitude and their relation to chronic mountain sickness[J ] . Med J Chinese PLA, 2014, 39(7): 576-580. DOI:10.11855/j.issn.0577-7402.2014.07.13.

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