Risk factors for hemorrhage in hospitalized premature infants: analysis of 615 cases

Yuanli CHEN; Ying XU

doi:10.16016/j.1000-5404.201701074

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Risk factors for hemorrhage in hospitalized premature infants: analysis of 615 cases

更新时间：2026-01-09

- Risk factors for hemorrhage in hospitalized premature infants: analysis of 615 cases
- Journal of Third Military Medical University Vol. 39, Issue 16, Pages: 1669-1672(2017)
- 作者机构：
- 作者简介：
- 基金信息：
  
  the National Clinical Key-discipline Construction Program of China(2013544)
- DOI：10.16016/j.1000-5404.201701074
  CLC：
- Received：12 January 2017，
  
  Published：30 August 2017
- 稿件说明：
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Yuanli CHEN, Ying XU. Risk factors for hemorrhage in hospitalized premature infants: analysis of 615 cases[J]. Journal of Third Military Medical University, 2017, 39(16): 1669-1672.
DOI：

Yuanli CHEN, Ying XU. Risk factors for hemorrhage in hospitalized premature infants: analysis of 615 cases[J]. Journal of Third Military Medical University, 2017, 39(16): 1669-1672. DOI： 10.16016/j.1000-5404.201701074.

摘要

Abstract

Objective

To analyze the related risk factors for premature infant hemorrhage.

Methods

A retrospective study was carried out on 615 hospitalized premature newborns in the Children's Hospital from January 2014 to January 2016. Their clinical data (including basic information

peri-natal factors

and bleeding) and laboratory results (coagulation indexes

platelet count

and white blood cell count) were collected. The infants were divided into 2 groups according to having or having not hemorrhage. Univariate analysis and logistic regression analysis were used to identify independent variables of considerable significance.

Results

Univariate analysis revealed that significant differences were found in prothrombin time (PT) and fibrinogen (FIB) between the 2 groups (

0.05

0.01)

but not in the gestational age

asphyxia history

white blood cell count

and platelet count. While multivariate logistic regression analysis showed that there were significant differences in gestational age

asphyxia resuscitation history

platelet count

white blood cell count and FIB value between the 2 groups (

0.05). Longer gestational age

and higher platelet count and FIB value were protective factors

while asphyxia resuscitation history and higher white blood cell count were risk factors.

Conclusion

Short gestational age

history of asphyxia resuscitation

high white blood cell count

and low platelet count and FIB value are risk factors for premature infants hemorrhage.

关键词

Keywords

references

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