Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion

Yi Wang; Shugui Shi; Kangning Chen; Jun Hu; Qu Liu; Long Lu; Shan Wen; Junwei Guo

doi:10.16016/j.1000-5404.201610036

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Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion

更新时间：2026-01-09

- Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion
- Journal of Third Military Medical University Vol. 39, Issue 6, Pages: 564-567(2017)
- 作者机构：
  
  1.400038 重庆，第三军医大学西南医院：神经内科
  2.400038 重庆，第三军医大学西南医院：心理科
- 作者简介：
- 基金信息：
- DOI：10.16016/j.1000-5404.201610036
  CLC： R741.05;R743;R749.1
- Received：08 October 2016，
  
  Revised：2016-11-05，
  
  Published：2017-06
- 稿件说明：
移动端阅览
Yi Wang, Shugui Shi, Kangning Chen, et al. Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion[J]. Journal of Third Military Medical University, 2017, 39(6): 564-567.
DOI：

Yi Wang, Shugui Shi, Kangning Chen, et al. Interventional recanalization improves cognitive function in patients with chronic total cerebrovascular occlusion[J]. Journal of Third Military Medical University, 2017, 39(6): 564-567. DOI： 10.16016/j.1000-5404.201610036.

摘要

目的

观察介入再通术对慢性闭塞性脑血管病变 (chronic total cerebrovascular occlusion，CTO) 患者认知功能的改善情况，并与未进行血管再通的CTO患者进行对比。

方法

选择我院2013年5月至2016年5月收治的CTO患者55例，其中介入再通组 (治疗组)21例，非再通组 (对照组)34例，比较术后12、24个月认知功能情况，采用简易智能精神状态检查量表 (mini-mental state examination，MMSE)、蒙特利尔认知功能评分表 (Montreal cognitive assessment，MoCA) 评估患者认知功能。

结果

治疗组与对照组患者术前美国国立卫生研究院卒中评分量表 (national institute of health stroke scale，NIHSS) 评分差异有统计学意义 (

0.05)，而性别、年龄、文化程度、脑血管危险因素、认知功能等基线资料差异没有统计学意义 (

0.05)。随访期间，两组患者认知功能 (12个月后MMSE、MoCA，24个月后MMSE、MoCA量表评分) 比较差异有统计学意义 (

0.05

0.01)。

结论

介入再通术可以明显改善CTO患者的认知功能。

Abstract

Objective

To investigate the efficacy of interventional recanalization in cognitive function in the patients with chronic total cerebrovascular occlusion (CTO).

Methods

Fifty-five patients with CTO admitted in our hospital from May 2013 to May 2016 were analyzed retrospectively

involving 21 recanalization patients as the treatment group and 34 non-recanalization patients as the control group. Mini-mental state examination (MMSE) and Montreal cognitive assessment (MoCA) were used to investigate the cognitive function in the first and second years after recanalization.

Results

There was difference in the national institute of health stroke scale (NIHSS) score between the treatment and control groups (4.80±3.76

2.71±2.92

0.05)

while there was no significant difference in baseline data including gender

age

culture level

cerebrovascular risk factors and cognitive function (

0.05). In the follow-up period

there wer

e significant differences in the cognitive function between the former and latter groups in MMSE

MoCA in the first year

and MMSE

and MoCA in the second year (

0.05

0.01).

Conclusion

The interventional recanalization can significantly improve cognitive function of the patients with CTO.

关键词

Keywords

references

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