LIU Chuan, et al. Relationship between testicular biopsy and serum FSH in azoospermia. [J]. Journal of Chongqing Medical University (5).(2005) DOI: 10.13406/j.cnki.cyxb.2005.05.019.
Relationship between testicular biopsy and serum FSH in azoospermia
Objective:To investigate the relationship between testicular biopsy and serum FSH(follicle stimulation hormone)in azoospermia and to discuss its significance.Methods:Testicular biopsies were obtained from 67 azoospermia men in order to distinguish the type of azoospermia.Serum FSH was measured by radioimmunoassy.Results:Four groups were identified by histopathology:normal spermatogenesis group(20cases)
hypospermatogenesis group(31cases)
germinal arrest group(19cases)ane Sertoli cell only syndrome group(17cases).Statistical significance of difference was detected between Steroli cell only syndrome group and the three other groups(normal spermatogenesis group
hypospermatogenesis group and germinal arrest group).No statistically significant differences were found among the three other groups.Conlusion:Elevation of serum FSH correlates only with Sertoli cell only syndrome.Serum FSH could not predict the other type of spermatogenetic damage exactly.Testicular biopsies could offer valuble help for diagnosis and treatment of azoospermia.
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