Efficacy of meniscal allograft transplantation combined with osteochondral autograft transplantation in treatment of lateral meniscal deficiency with concomitant cartilage lesions

Wu Chengjian; Lian Chengjie; Wu Zhengru; Chen Zhi; Qin Hao; Zhou Aiguo; Zhang Hua

doi:10.13406/j.cnki.cyxb.004006

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Efficacy of meniscal allograft transplantation combined with osteochondral autograft transplantation in treatment of lateral meniscal deficiency with concomitant cartilage lesions

Clinical research | 更新时间：2026-03-19

- Efficacy of meniscal allograft transplantation combined with osteochondral autograft transplantation in treatment of lateral meniscal deficiency with concomitant cartilage lesions
- Journal of Chongqing Medical University Vol. 51, Issue 3, Pages: 426-430(2026)
- 作者机构：
  
  1.福建医科大学附属协和医院运动损伤科，福州 350001
  2.重庆医科大学附属第一医院骨科，重庆 400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.004006
  CLC： R681.5
- Received：22 July 2025，
  
  Revised：2025-11-16，
  
  Accepted：18 November 2025，
  
  Published：28 March 2026
- 稿件说明：
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吴程键，连成杰，吴政儒，等.同种异体半月板移植联合骨软骨移植治疗外侧半月板缺损合并软骨损伤的疗效研究[J].重庆医科大学学报，2026，51（3）：426-430.

Wu Chengjian,Lian Chengjie,Wu Zhengru,et al.Efficacy of meniscal allograft transplantation combined with osteochondral autograft transplantation in treatment of lateral meniscal deficiency with concomitant cartilage lesions[J].Journal of Chongqing Medical University,2026,51(3):426-430.
吴程键，连成杰，吴政儒，等.同种异体半月板移植联合骨软骨移植治疗外侧半月板缺损合并软骨损伤的疗效研究[J].重庆医科大学学报，2026，51（3）：426-430. DOI： 10.13406/j.cnki.cyxb.004006.

Wu Chengjian,Lian Chengjie,Wu Zhengru,et al.Efficacy of meniscal allograft transplantation combined with osteochondral autograft transplantation in treatment of lateral meniscal deficiency with concomitant cartilage lesions[J].Journal of Chongqing Medical University,2026,51(3):426-430. DOI： 10.13406/j.cnki.cyxb.004006.

摘要

目的

探讨同期外侧半月板同种异体移植联合骨软骨移植术治疗外侧半月板缺损合并软骨损伤的临床疗效。

方法

回顾性分析2014年1月至2020年12月重庆医科大学附属第一医院收治的14例因外侧半月板缺失伴膝关节软骨损伤行膝关节外侧半月板移植联合马赛克自体软骨移植患者的临床资料。其中男5例，女9例，年龄（30.8±11.4）岁，左侧膝关节及右侧膝关节各7例。记录分析手术时间、手术并发症，术前、术后6个月、1年、2年及5年的Lysholm评分、视觉模拟量表（visual analogue scale，VAS）评分及Tegner评分。术后6个月、1年及以后每年复查MRI评估移植半月板及关节软骨情况。

结果

所有14例患者完成随访，中位随访时间为6年（范围：3~10年）。手术时间为（174.6±38.8） min。与术前比较，术后患者的Lysholm评分、Tegner评分及VAS评分明显改善（

0.05），且术后膝关节功能及疼痛持续改善（

0.05）。至末次随访，13例患者移植半月板完整，移植成功；1例发生移植半月板撕裂（

1/2），视为移植失败；通过MRI对移植软骨的术后生长情况采用Recht分级标准进行评估：0级2例，1级8例，2级2例，3级1例，4级1例。

结论

外侧半月板与骨软骨联合移植是治疗外侧半月板缺损合并软骨损伤的有效方案，可确切改善膝关节功能。

Abstract

Objective

To investigate the efficacy of lateral meniscal allograft transplantation（MAT） combined with osteochondral autograft transplantation in the treatment of lateral meniscal deficiency with concomitant cartilage lesions.

Methods

A retrospective analysis was performed for the clinical data of 14 patients who underwent lateral MAT combined with autologous osteochondral mosaicplasty due to lateral meniscal deficiency with concomitant cartilage lesions in The First Affiliated Hospital of Chongqing Medical University from January 2014 to December 2020. Among the 14 patients，there were 5 male patients and 9 female patients，with an age of 30.8±11.4 years，and there were 7 cases of disease in the left knee joint and 7 cases of disease in the right knee joint. Time of operation and surgical complications were recorded，and Lysholm score，Visual Analogue Scale （VAS） score，and Tegner score were recorded before surgery and at 6 months，1 year，2 years，and 5 years after surgery. MRI reexamination was performed to evaluate graft integrity and cartilage repair at 6 months，1 year，and annually since then after surgery.

Results

All 14 patients completed follow-up，with a median follow-up time of 6 years（range 3-10 years）. The mean time of operation was （174.6±38.8） minutes. After treatment，all patients had significant improvements in Lysholm score，Tegner score，and VAS score（

0.05），with continuous improvements in knee function and pain after surgery（

0.05）. At the last follow-up，13 patients had an intact meniscal graft，indicating successful transplantation，and 1 patient had a tear extending over 1/2 of the meniscal graft，indicating failed transplantation. MRI assessment of cartilage repair showed Recht grade 0 cartilage lesion in 2 patients，grade 1 cartilage lesion in 8 patients，grade 2 cartilage lesion in 2 patients，grade 3 cartilage lesion in 1 patient，and grade 4 cartilage lesion in 1 patient.

Conclusion

Lateral MAT combined with osteochondral autograft transplantation has a satisfactory effect in the treatment of lateral meniscal deficiency with concomitant cartilage lesions and can significantly improve knee function.

关键词

Keywords

references

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