Zhang Yue,Ma Jingmiao,Hu Zhongsheng,et al.Current research progress on IL-27 in the pathogenesis of diminished ovarian reserve[J].Journal of Chongqing Medical University,2026,51(3):395-399.
Zhang Yue,Ma Jingmiao,Hu Zhongsheng,et al.Current research progress on IL-27 in the pathogenesis of diminished ovarian reserve[J].Journal of Chongqing Medical University,2026,51(3):395-399. DOI: 10.13406/j.cnki.cyxb.003994.
Current research progress on IL-27 in the pathogenesis of diminished ovarian reserve
With societal development,an increasing number of women are opting for delayed marriage and childbearing,leading to a sustained rise in the proportion of advanced maternal age. Consequently,there has been a marked increase in the incidence of diminished ovarian reserve(DOR) among women of reproductive age. Therefore,elucidating the pathogenesis of DOR at an early stage and achieving early diagnosis and treatment are crucial for better preserving female fertility. This review summarizes the role of the interleukin-12 family cytokine interleukin-27 in the pathogenesis of DOR and the current status of clinical research,providing new clinical perspectives for the diagnosis and treatment of DOR.
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