Received:03 August 2025,
Revised:2025-09-02,
Accepted:05 September 2025,
Published:28 September 2025
移动端阅览
中国研究型医院学会糖尿病学专业委员会.超重或肥胖成人实体器官移植受者体重管理专家共识(2025版)[J].重庆医科大学学报,2025,50(9):1156-1177.
.Expert consensus on weight management for overweight and obese adult solid organ transplant recipients (2025 edition)[J].Journal of Chongqing Medical University,2025,50(9):1156-1177.
中国研究型医院学会糖尿病学专业委员会.超重或肥胖成人实体器官移植受者体重管理专家共识(2025版)[J].重庆医科大学学报,2025,50(9):1156-1177. DOI: 10.13406/j.cnki.cyxb.003934.
.Expert consensus on weight management for overweight and obese adult solid organ transplant recipients (2025 edition)[J].Journal of Chongqing Medical University,2025,50(9):1156-1177. DOI: 10.13406/j.cnki.cyxb.003934.
近年来,实体器官移植受者合并超重/肥胖的患病率快速上升,实体器官移植受者合并肥胖的临床研究证据日益增多,但缺乏相应的规范诊疗及综合管理路径指导临床实践。基于此,由中国研究型医院学会糖尿病学专业委员会组织专家编写了《超重或肥胖成人实体器官移植受者体重管理专家共识(2025版)》。本共识主要围绕实体器官移植受者超重/肥胖的流行病学资料、诊断标准、筛查及评估方法、管理路径、干预策略等方面给出推荐意见,以期进一步提高广大从事器官移植全程管理的医务工作者对实体器官移植合并超重/肥胖人群的管理水平,规范临床诊疗,改善患者预后,提高生活质量。
The prevalence of overweight/obesity among solid organ transplant recipients has increased rapidly. Although clinical research evidence on obesity in this population has accumulated, there remains a lack of standardized diagnostic, therapeutic, and comprehensive management pathways to guide clinical practice. To address this gap, the Diabetes Professional Committee of the Chinese Research Hospital Association organized experts to develop the Expert Consensus on Weight Management for Adult Solid Organ Transplant Recipients with Overweight or Obesity (2025 Edition). This consensus provides recommendations regarding the epidemiology, diagnostic criteria, screening and evaluation methods, management pathways, and intervention strategies for overweight/obesity in solid organ transplant recipients. It aims to enhance the ability of healthcare professionals involved in the entire process of organ transplantation to manage overweight/obesity in this population, standardize clinical practice, improve patient prognosis, and enhance quality of life.
黄洁夫 . 中国器官移植发展报告-2021 [M ] . 北京 : 人民卫生出版社 , 2022 : 7 - 26 .
Huang JF . China organ transplantation development report-2021 [M ] . Beijing : People’s Medical Publishing House , 2022 : 7 - 26 .
Bhat M , Usmani SE , Azhie A , et al . Metabolic consequences of solid organ transplantation [J ] . Endocr Rev , 2021 , 42 ( 2 ): 171 - 197 .
Ghanem OM , Pita A , Nazzal M , et al . Obesity,organ failure,and transplantation:a review of the role of metabolic and bariatric surgery in transplant candidates and recipients [J ] . Surg Endosc , 2024 , 38 ( 8 ): 4138 - 4151 .
Delacôte C , Favre M , El Amrani M , et al . Morbid obesity increases death and dropout from the liver transplantation waiting list:a prospective cohort study [J ] . United European Gastroenterol J , 2022 , 10 ( 4 ): 396 - 408 .
Anastácio LR , Lima AS , Toulson Davisson Correia MI . Metabolic syndrome and its components after liver transplantation:incidence,prevalence,risk factors,and implications [J ] . Clin Nutr , 2010 , 29 ( 2 ): 175 - 179 .
Jiménez-Pérez M , González-Grande R , Omonte Guzmán E , et al . Metabolic complications in liver transplant recipients [J ] . World J Gastroenterol , 2016 , 22 ( 28 ): 6416 - 6423 .
Kugler C , Einhorn I , Gottlieb J , et al . Postoperative weight gain during the first year after kidney,liver,heart,and lung transplant:a prospective study [J ] . Prog Transplant , 2015 , 25 ( 1 ): 49 - 55 .
Beckmann S , Denhaerynck K , Stampf S , et al . New-onset obesity after liver transplantation-outcomes and risk factors:the Swiss Transplant Cohort Study [J ] . Transpl Int , 2018 , 31 ( 11 ): 1254 - 1267 .
van Son J , Stam SP , Gomes-Neto AW , et al . Post-transplant obesity impacts long-term survival after liver transplantation [J ] . Metabolism , 2020 , 106 : 154204 .
Obesity : preventing and managing the global epidemic . Report of a WHO consultation [J ] . World Health Organ Tech Rep Ser , 2000 , 894 : 1 - 253 .
Zhou BF , Cooperative Meta-Analysis Group of the Working Group on Obesity in China . Predictive values of body mass index and waist circumference for risk factors of certain related diseases in Chinese adults:study on optimal cut-off points of body mass index and waist circumference in Chinese adults [J ] . Biomed Environ Sci , 2002 , 15 ( 1 ): 83 - 96 .
中华人民共和国国家卫生健康委员会医政司 . 肥胖症诊疗指南(2024年版) [J ] . 中华消化外科杂志 , 2024 , 23 ( 10 ): 1237 - 1260 .
Medical Administration Bureau of National Health Commission of the People's Republic of China . Guidelines for the Diagnosis and Treatment of Obesity (2024 Edition) [J ] . Chin J Dig Surg , 2024 , 23 ( 10 ): 1237 - 1260 .
World Obesity Federation . World obesity atlas 2025 [EB/OL ] . [ 2025-05-12 ] . https://data.worldobesity.org/publications/ cat=23 https://data.worldobesity.org/publications/cat=23 .
Aziz F , Ramadorai A , Parajuli S , et al . Obesity:an independent predictor of morbidity and graft loss after kidney transplantation [J ] . Am J Nephrol , 2020 , 51 ( 8 ): 615 - 623 .
Kardashian AA , Dodge JL , Roberts J , et al . Weighing the risks:Morbid obesity and diabetes are associated with increased risk of death on the liver transplant waiting list [J ] . Liver Int , 2018 , 38 ( 3 ): 553 - 563 .
Nöhre M , Schieffer E , Hanke A , et al . Obesity after kidney transplantation-results of a KTx360°Substudy [J ] . Front Psychiatry , 2020 , 11 : 399 .
Ahmed Z , Khan MA , Vazquez-Montesino LM , et al . Bariatric surgery,obesity and liver transplantation [J ] . Transl Gastroenterol Hepatol , 2022 , 7 : 25 .
Cremona S , Llerena GC , de Hollanda A , et al . Obesity is increasing in liver transplant recipients and exacerbates cardiovascular risk:a single-centre European study [J ] . Obes Surg , 2024 , 34 ( 12 ): 4442 - 4451 .
Jomphe V , Bélanger N , Beauchamp-Parent C , et al . New-onset obesity after lung transplantation:incidence,risk factors,and clinical outcomes [J ] . Transplantation , 2022 , 106 ( 11 ): 2247 - 2255 .
Chouairi F , Milner A , Sen S , et al . Impact of obesity on heart transplantation outcomes [J ] . J Am Heart Assoc , 2021 , 10 ( 23 ): e021346 .
Saab S , Lalezari D , Pruthi P , et al . The impact of obesity on patient survival in liver transplant recipients:a meta-analysis [J ] . Liver Int , 2015 , 35 ( 1 ): 164 - 170 .
Lafranca JA , IJermans JNM , Betjes MGH , et al . Body mass index and outcome in renal transplant recipients:a systematic review and meta-analysis [J ] . BMC Med , 2015 , 13 : 111 .
Ahmadi SF , Zahmatkesh G , Streja E , et al . Body mass index and mortality in kidney transplant recipients:a systematic review and meta-analysis [J ] . Am J Nephrol , 2014 , 40 ( 4 ): 315 - 324 .
Sood A , Hakim DN , Hakim NS . Consequences of recipient obesity on postoperative outcomes in a renal transplant:a systematic review and meta-analysis [J ] . Exp Clin Transplant , 2016 , 14 ( 2 ): 121 - 128 .
Chadban SJ , Ahn C , Axelrod DA , et al . KDIGO clinical practice guideline on the evaluation and management of candidates for kidney transplantation [J ] . Transplantation , 2020 ,104( 4 S1 Suppl 1 ): S11 - S103 .
中华医学会器官移植学分会 . 中国肾脏移植术前准备操作指南(2023版) [J ] . 中华器官移植杂志 , 2024 , 45 ( 9 ): 563 - 572 .
Chinese Society of Organ Transplantation . Chinese guidelines for preoperative preparation of kidney transplantation(2023 edition) [J ] . Chin J Organ Transplant , 2024 , 45 ( 9 ): 563 - 572 .
Mehra MR , Canter CE , Hannan MM , et al . The 2016 International Society for Heart Lung Transplantation listing criteria for heart transplantation:a 10-year update [J ] . J Heart Lung Transplant , 2016 , 35 ( 1 ): 1 - 23 .
Leard LE , Holm AM , Valapour M , et al . Consensus document for the selection of lung transplant candidates:an update from the International Society for Heart and Lung Transplantation [J ] . J Heart Lung Transplant , 2021 , 40 ( 11 ): 1349 - 1379 .
Mazali FC , Mazzali M . Uric acid and transplantation [J ] . Semin Nephrol , 2011 , 31 ( 5 ): 466 - 471 .
Anastácio LR , deS Ribeiro H , Ferreira LG , et al . Incidence and risk factors for diabetes,hypertension and obesity after liver transplantation [J ] . Nutr Hosp , 2013 , 28 ( 3 ): 643 - 648 .
Healy AH , Stehlik J , Edwards LB , et al . Predictors of 30-day post-transplant mortality in patients bridged to transplantation with continuous-flow left ventricular assist devices:an analysis of the International Society for Heart and Lung Transplantation Transplant Registry [J ] . J Heart Lung Transplant , 2016 , 35 ( 1 ): 34 - 39 .
Kilic A , Conte JV , Shah AS , et al . Orthotopic heart transplantation in patients with metabolic risk factors [J ] . Ann Thorac Surg , 2012 , 93 ( 3 ): 718 - 724 .
Upala S , Panichsillapakit T , Wijarnpreecha K , et al . Underweight and obesity increase the risk of mortality after lung transplantation:a systematic review and meta-analysis [J ] . Transpl Int , 2016 , 29 ( 3 ): 285 - 296 .
Choudhary NS , Saigal S , Saraf N , et al . Sarcopenic obesity with metabolic syndrome:a newly recognized entity following living donor liver transplantation [J ] . Clin Transplant , 2015 , 29 ( 3 ): 211 - 215 .
Colle I , Van Vlierberghe H , Troisi R , et al . Transplanted liver:consequences of denervation for liver functions [J ] . Anat Rec A Discov Mol Cell Evol Biol , 2004 , 280 ( 1 ): 924 - 931 .
Beckmann S , Drent G , Ruppar T , et al . Pre- and post-transplant factors associated with body weight parameters after liver transplantation- A systematic review and meta-analysis [J ] . Transplant Rev(Orlando) , 2019 , 33 ( 1 ): 39 - 47 .
Taşdemir D , Aksoy N . Weight gain,energy intake,energy expenditure,and immunosuppressive therapy in kidney transplant recipients [J ] . Prog Transplant , 2020 , 30 ( 4 ): 322 - 328 .
Ferreira SC , de Oliveira Penaforte FR , Cardoso A , et al . Association of food cravings with weight gain,overweight,and obesity in patients after liver transplantation [J ] . Nutrition , 2020 , 69 : 110573 .
Richardson RA , Garden OJ , Davidson HI . Reduction in energy expenditure after liver transplantation [J ] . Nutrition , 2001 , 17 ( 7/8 ): 585 - 589 .
Vrieze A , Van Nood E , Holleman F , et al . Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome [J ] . Gastroenterology , 2012 , 143 ( 4 ): 913 - 916 .
Meier-Kriesche HU , Arndorfer JA , Kaplan B . The impact of body mass index on renal transplant outcomes:a significant independent risk factor for graft failure and patient death [J ] . Transplantation , 2002 , 73 ( 1 ): 70 - 74 .
Kovesdy CP , Czira ME , Rudas A , et al . Body mass index,waist circumference and mortality in kidney transplant recipients [J ] . Am J Transplant , 2010 , 10 ( 12 ): 2644 - 2651 .
杨雁 , 陈颖 , 张惠杰 , 等 . 糖尿病患者体重管理专家共识(2024版) [J ] . 中华糖尿病杂志 , 2024 , 16 ( 9 ): 959 - 971 .
Yang Y , Chen Y , Zhang HJ , et al . Expert consensus on weight management for patients with diabetes mellitus(2024 edition) [J ] . Chin J Diabetes Mellits , 2024 , 16 ( 9 ): 959 - 971 .
Anastácio LR , Ferreira LG , Ribeiro HS , et al . Sarcopenia,obesity and sarcopenic obesity in liver transplantation:a body composition prospective study [J ] . Arq Bras Cir Dig , 2019 , 32 ( 2 ): e1434 .
中华医学会健康管理学分会 , 中国营养学会临床营养分会 , 全国卫生产业企业管理协会医学营养产业分会 , 等 . 超重或肥胖人群体重管理流程的专家共识(2021年) [J ] . 中华健康管理学杂志 , 2021 , 15 ( 4 ): 317 - 322 .
Chinese Society of Health Management , Chinese Society for Clinical Nutrition , Medical Nutrition Industry Branch of National Association of Health Industry and Enterprise Management , et al . Expert consensus on weight management process for overweight or obese populations(2021) [J ] . Chin J Health Manag , 2021 , 15 ( 4 ): 317 - 322 .
Ahmed SH , Biddle K , Augustine T , et al . Post-transplantation diabetes mellitus [J ] . Diabetes Ther , 2020 , 11 ( 4 ): 779 - 801 .
Newman JD , Schlendorf KH , Cox ZL , et al . Post-transplant diabetes mellitus following heart transplantation [J ] . J Heart Lung Transplant , 2022 , 41 ( 11 ): 1537 - 1546 .
Yates CJ , Fourlanos S , Colman PG , et al . Divided dosing reduces prednisolone-induced hyperglycaemia and glycaemic variability:a randomized trial after kidney transplantation [J ] . Nephrol Dial Transplant , 2014 , 29 ( 3 ): 698 - 705 .
中国研究型医院学会糖尿病学专业委员会 , 中华医学会糖尿病学分会 , 北京医学会糖尿病学分会 . 实体器官移植后糖尿病患者降糖药物应用专家共识(2024版) [J ] . 中华糖尿病杂志 , 2024 , 16 ( 4 ): 404 - 420 .
Chinese Diabetes Society of Chinese Research Hospital Association , Chinese Diabetes Society , Beijing Diabetes Society . Expert consensus on the use of glucose-lowering medications in patients with diabetes after solid organ transplantation(2024 edition) [J ] . Chin J Diabetes Mellit , 2024 , 16 ( 4 ): 404 - 420 .
Hüsing A , Kabar I , Schmidt HH . Lipids in liver transplant recipients [J ] . World J Gastroenterol , 2016 , 22 ( 12 ): 3315 - 3324 .
中华医学会器官移植学分会 . 中国实体器官移植受者血脂管理规范(2019版) [J ] . 器官移植 , 2019 , 10 ( 2 ): 101 - 111 .
Chinese Society of Organ Transplantation . Guideline for lipid management in Chinese solid organ transplant recipients(2019 edition) [J ] . Org Transplant , 2019 , 10 ( 2 ): 101 - 111 .
Saeed N , Glass L , Sharma P , et al . Incidence and risks for nonalcoholic fatty liver disease and steatohepatitis post-liver transplant:systematic review and meta-analysis [J ] . Transplantation , 2019 , 103 ( 11 ): e345 - e354 .
Kosuta I , Ostojic A , Brajkovic AV , et al . Shifting perspectives in liver diseases after kidney transplantation [J ] . World J Hepatol , 2023 , 15 ( 7 ): 883 - 896 .
高逢强 , 汪恺 , 董立彬 , 等 . 脂肪变性供肝肝移植受者预后分析的多中心临床研究 [J ] . 中华器官移植杂志 , 2023 , 44 ( 1 ): 23 - 30 .
Gao FQ , Wang K , Dong LB , et al . A multicenter clinical study on the prognosis of liver transplant recipients with steatotic donor livers [J ] . Chin J Organ Transplant , 2023 , 44 ( 1 ): 23 - 30 .
van Werven JR , Marsman HA , Nederveen AJ , et al . Assessment of hepatic steatosis in patients undergoing liver resection:comparison of US,CT,T1-weighted dual-echo MR imaging,and point-resolved 1H MR spectroscopy [J ] . Radiology , 2010 , 256 ( 1 ): 159 - 168 .
Karlas T , Kollmeier J , Böhm S , et al . Noninvasive characterization of graft steatosis after liver transplantation [J ] . Scand J Gastroenterol , 2015 , 50 ( 2 ): 224 - 232 .
Germani G , Laryea M , Rubbia-Brandt L , et al . Management of recurrent and de novo NAFLD/NASH after liver transplantation [J ] . Transplantation , 2019 , 103 ( 1 ): 57 - 67 .
Tantisattamo E , Kalantar-Zadeh K , Halleck F , et al . Novel approaches to sarcopenic obesity and weight management before and after kidney transplantation [J ] . Curr Opin Nephrol Hypertens , 2021 , 30 ( 1 ): 14 - 26 .
Sessa A , Esposito A , Iavicoli GD , et al . Immunosuppressive agents and bone disease in renal transplant patients with hypercalcemia [J ] . Transplant Proc , 2010 , 42 ( 4 ): 1148 - 1155 .
Satilmis B , Akbulut S , Sahin TT , et al . Assessment of liver regeneration in patients who have undergone living donor hepatectomy for living donor liver transplantation [J ] . Vaccines(Basel) , 2023 , 11 ( 2 ): 244 .
Aktaş A . Transplanted kidney function evaluation [J ] . Semin Nucl Med , 2014 , 44 ( 2 ): 129 - 145 .
Ribeiro RVP , Alvarez JS , Yu F , et al . Comparing donor heart assessment strategies during ex situ heart perfusion to better estimate posttransplant cardiac function [J ] . Transplantation , 2020 , 104 ( 9 ): 1890 - 1898 .
Dziubek W , Pawlaczyk W , Rogowski L , et al . Assessment of depression and anxiety in patients with chronic kidney disease and after kidney transplantation-a comparative analysis [J ] . Int J Environ Res Public Health , 2021 , 18 ( 19 ): 10517 .
de Wit L , Luppino F , van Straten A , et al . Depression and obesity:a meta-analysis of community-based studies [J ] . Psychiatry Res , 2010 , 178 ( 2 ): 230 - 235 .
Rimmer B , Jenkins R , Russell S , et al . Assessing quality of life in solid organ transplant recipients:a systematic review of the development,content,and quality of available condition- and transplant-specific patient-reported outcome measures [J ] . Transplant Rev(Orlando) , 2024 , 38 ( 2 ): 100836 .
Krasnoff JB , Vintro AQ , Ascher NL , et al . Objective measures of health-related quality of life over 24 months post-liver transplantation [J ] . Clin Transplant , 2005 , 19 ( 1 ): 1 - 9 .
Krasnoff JB , Vintro AQ , Ascher NL , et al . A randomized trial of exercise and dietary counseling after liver transplantation [J ] . Am J Transplant , 2006 , 6 ( 8 ): 1896 - 1905 .
Hickman IJ , Hannigan AK , Johnston HE , et al . Telehealth-delivered,cardioprotective diet and exercise program for liver transplant recipients:a randomized feasibility study [J ] . Transplant Direct , 2021 , 7 ( 3 ): e667 .
Osté MCJ , Gomes-Neto AW , Corpeleijn E , et al . Dietary Approach to Stop Hypertension(DASH) diet and risk of renal function decline and all-cause mortality in renal transplant recipients [J ] . Am J Transplant , 2018 , 18 ( 10 ): 2523 - 2533 .
Janaudis-Ferreira T , Tansey CM , Mathur S , et al . The effects of exercise training in adult solid organ transplant recipients:a systematic review and meta-analysis [J ] . Transpl Int , 2021 , 34 ( 5 ): 801 - 824 .
Langer D , Burtin C , Schepers L , et al . Exercise training after lung transplantation improves participation in daily activity:a randomized controlled trial [J ] . Am J Transplant , 2012 , 12 ( 6 ): 1584 - 1592 .
Bernardi L , Radaelli A , Passino C , et al . Effects of physical training on cardiovascular control after heart transplantation [J ] . Int J Cardiol , 2007 , 118 ( 3 ): 356 - 362 .
Painter PL , Hector L , Ray K , et al . Effects of exercise training on coronary heart disease risk factors in renal transplant recipients [J ] . Am J Kidney Dis , 2003 , 42 ( 2 ): 362 - 369 .
Janaudis-Ferreira T , Mathur S , Deliva R , et al . Exercise for solid organ transplant candidates and recipients:a joint position statement of the Canadian society of transplantation and CAN-RESTORE [J ] . Transplantation , 2019 , 103 ( 9 ): e220 - e238 .
Colman E . Food and drug administration’s obesity drug guidance document:a short history [J ] . Circulation , 2012 , 125 ( 17 ): 2156 - 2164 .
Chakhtoura M , Haber R , Ghezzawi M , et al . Pharmacotherapy of obesity:an update on the available medications and drugs under investigation [J ] . EClinicalMedicine , 2023 , 58 : 101882 .
Zeng Q , Li NS , Pan XF , et al . Clinical management and treatment of obesity in China [J ] . Lancet Diabetes Endocrinol , 2021 , 9 ( 6 ): 393 - 405 .
中华医学会健康管理学分会 , 中国营养学会 , 中国医疗保健国际交流促进会生殖医学分会 , 等 . 超重或肥胖人群体重管理专家共识及团体标准 [J ] . 中华健康管理学杂志 , 2018 , 12 ( 3 ): 200 - 207 .
Chinese Society of Health Management , Chinese Nutrition Society , Reproductive Medicine Branch of China International Exchange and Promotive Association for Medical and Health Care , et al . Expert consensus and group standard for weight management in overweight or obese populations [J ] . Chin J Health Manag , 2018 , 12 ( 3 ): 200 - 207 .
Torgerson JS , Hauptman J , Boldrin MN , et al . XENical in the prevention of diabetes in obese subjects(XENDOS) study:a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients [J ] . Diabetes Care , 2004 , 27 ( 1 ): 155 - 161 .
史轶蘩 , 邓洁英 , 朱文玲 , 等 . 奥利司他对中国肥胖患者的疗效和安全性分析 [J ] . 中华内分泌代谢杂志 , 2001 , 17 ( 6 ): 383 - 387 .
Shi YF , Deng JY , Zhu WL , et al . Efficacy and safety analysis of orlistat in Chinese obese patients [J ] . Chin J Endocrinol Metab , 2001 , 17 ( 6 ): 383 - 387 .
Gadde KM , Allison DB , Ryan DH , et al . Effects of low-dose,controlled-release,phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (CONQUER):a randomised,placebo-controlled,phase 3 trial [J ] . Lancet , 2011 , 377 ( 9774 ): 1341 - 1352 .
Allison DB , Gadde KM , Garvey WT , et al . Controlled-release phentermine/topiramate in severely obese adults:a randomized controlled trial(EQUIP) [J ] . Obesity(Silver Spring) , 2012 , 20 ( 2 ): 330 - 342 .
Oniscu GC , Abramowicz D , Bolignano D , et al . Management of obesity in kidney transplant candidates and recipients:a clinical practice guideline by the DESCARTES Working Group of ERA [J ] . Nephrol Dial Transplant , 2021 , 37 ( Suppl 1 ): i1 - i15 .
Apovian CM , Aronne L , Rubino D , et al . A randomized,phase 3 trial of naltrexone SR/bupropion SR on weight and obesity-related risk factors(COR-Ⅱ) [J ] . Obesity (Silver Spring) , 2013 , 21 ( 5 ): 935 - 943 .
Pi-Sunyer X , Astrup A , Fujioka K , et al . A randomized,controlled trial of 3.0 Mg of liraglutide in weight management [J ] . N Engl J Med , 2015 , 373 ( 1 ): 11 - 22 .
Astrup A , Rössner S , Van Gaal L , et al . Effects of liraglutide in the treatment of obesity:a randomised,double-blind,placebo-controlled study [J ] . Lancet , 2009 , 374 ( 9701 ): 1606 - 1616 .
Wharton S , Liu A , Pakseresht A , et al . Real-world clinical effectiveness of liraglutide 3.0 Mg for weight management in Canada [J ] . Obesity(Silver Spring) , 2019 , 27 ( 6 ): 917 - 924 .
Park JH , Kim JY , Choi JH , et al . Effectiveness of liraglutide 3 Mg for the treatment of obesity in a real-world setting without intensive lifestyle intervention [J ] . Int J Obes(Lond) , 2021 , 45 ( 4 ): 776 - 786 .
Haase CL , Serratore Achenbach MG , Lucrezi G , et al . Use of liraglutide 3.0 Mg for weight management in a real-world setting in Switzerland [J ] . Obes Facts , 2021 , 14 ( 5 ): 568 - 576 .
Feng P , Yu DM , Chen LM , et al . Liraglutide reduces the body weight and waist circumference in Chinese overweight and obese type 2 diabetic patients [J ] . Acta Pharmacol Sin , 2015 , 36 ( 2 ): 200 - 208 .
Chen K , Chen L , Shan ZY , et al . Beinaglutide for weight management in Chinese individuals with overweight or obesity:a phase 3 randomized controlled clinical study [J ] . Diabetes Obes Metab , 2024 , 26 ( 2 ): 690 - 698 .
Kadowaki T , Isendahl J , Khalid U , et al . Semaglutide once a week in adults with overweight or obesity,with or without type 2 diabetes in an East Asian population(STEP 6):a randomised,double-blind,double-dummy,placebo-controlled,phase 3a trial [J ] . Lancet Diabetes Endocrinol , 2022 , 10 ( 3 ): 193 - 206 .
Garvey WT , Batterham RL , Bhatta M , et al . Two-year effects of semaglutide in adults with overweight or obesity:the STEP 5 trial [J ] . Nat Med , 2022 , 28 ( 10 ): 2083 - 2091 .
Rubino D , Abrahamsson N , Davies M , et al . Effect of continued weekly subcutaneous semaglutide vs placebo on weight loss maintenance in adults with overweight or obesity:the STEP 4 randomized clinical trial [J ] . JAMA , 2021 , 325 ( 14 ): 1414 - 1425 .
Wilding JPH , Batterham RL , Calanna S , et al . Once-weekly semaglutide in adults with overweight or obesity [J ] . N Engl J Med , 2021 , 384 ( 11 ): 989 - 1002 .
Davies M , Færch L , Jeppesen OK , et al . Semaglutide 2·4 Mg once a week in adults with overweight or obesity,and type 2 diabetes (STEP 2):a randomised,double-blind,double-dummy,placebo-controlled,phase 3 trial [J ] . Lancet , 2021 , 397 ( 10278 ): 971 - 984 .
Wadden TA , Bailey TS , Billings LK , et al . Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity:the STEP 3 randomized clinical trial [J ] . JAMA , 2021 , 325 ( 14 ): 1403 - 1413 .
Mu YM , Bao XL , Eliaschewitz FG , et al . Efficacy and safety of once weekly semaglutide 2·4 Mg for weight management in a predominantly East Asian population with overweight or obesity(STEP 7):a double-blind,multicentre,randomised controlled trial [J ] . Lancet Diabetes Endocrinol , 2024 , 12 ( 3 ): 184 - 195 .
le Roux CW , Zhang SY , Aronne LJ , et al . Tirzepatide for the treatment of obesity:rationale and design of the SURMOUNT clinical development program [J ] . Obesity (Silver Spring) , 2023 , 31 ( 1 ): 96 - 110 .
Zhao L , Cheng ZF , Lu YB , et al . Tirzepatide for weight reduction in Chinese adults with obesity:the SURMOUNT-CN randomized clinical trial [J ] . JAMA , 2024 , 332 ( 7 ): 551 - 560 .
Ji LN , Jiang HW , Bi Y , et al . Once-weekly mazdutide in Chinese adults with obesity or overweight [J ] . N Engl J Med , 2025 , 392 ( 22 ): 2215 - 2225 .
Collet TH , Dubern B , Mokrosinski J , et al . Evaluation of a melanocortin-4 receptor(MC4R) agonist(Setmelanotide) in MC4R deficiency [J ] . Mol Metab , 2017 , 6 ( 10 ): 1321 - 1329 .
Haqq AM , Chung WK , Dollfus H , et al . Efficacy and safety of setmelanotide,a melanocortin-4 receptor agonist,in patients with Bardet-Biedl syndrome and Alström syndrome:a multicentre,randomised,double-blind,placebo-controlled,phase 3 trial with an open-label period [J ] . Lancet Diabetes Endocrinol , 2022 , 10 ( 12 ): 859 - 868 .
Markham A . Setmelanotide:first approval [J ] . Drugs , 2021 , 81 ( 3 ): 397 - 403 .
Moon HS , Huh JY , Dincer F , et al . Identification and saturable nature of signaling pathways induced by metreleptin in humans:comparative evaluation of in vivo , ex vivo ,and in vitro administration [J ] . Diabetes , 2015 , 64 ( 3 ): 828 - 839 .
Chou K , Perry CM . Metreleptin:first global approval [J ] . Drugs , 2013 , 73 ( 9 ): 989 - 997 .
Grover A , Quaye E , Brychta RJ , et al . Leptin decreases energy expenditure despite increased thyroid hormone in patients with lipodystrophy [J ] . J Clin Endocrinol Metab , 2021 , 106 ( 10 ): e4163 - e4178 .
MacLaughlin HL , Cook SA , Kariyawasam D , et al . Nonrandomized trial of weight loss with orlistat,nutrition education,diet,and exercise in obese patients with CKD:2-year follow-up [J ] . Am J Kidney Dis , 2010 , 55 ( 1 ): 69 - 76 .
MacLaughlin HL , Hall WL , Condry J , et al . Participation in a structured weight loss program and all-cause mortality and cardiovascular morbidity in obese patients with chronic kidney disease [J ] . J Ren Nutr , 2015 , 25 ( 6 ): 472 - 479 .
Filippatos TD , Derdemezis CS , Gazi IF , et al . Orlistat-associated adverse effects and drug interactions:a critical review [J ] . Drug Saf , 2008 , 31 ( 1 ): 53 - 65 .
Singh A , Sarkar SR , Gaber LW , et al . Acute oxalate nephropathy associated with orlistat,a gastrointestinal lipase inhibitor [J ] . Am J Kidney Dis , 2007 , 49 ( 1 ): 153 - 157 .
Coutinho AK , Glancey GR . Orlistat,an under-recognised cause of progressive renal impairment [J ] . Nephrol Dial Transplant , 2013 , 28 ( Suppl 4 ): iv172 - iv174 .
Montero JL , Muntané J , Fraga E , et al . Orlistat associated subacute hepatic failure [J ] . J Hepatol , 2001 , 34 ( 1 ): 173 .
Evans S , Michael R , Wells H , et al . Drug interaction in a renal transplant patient:cyclosporin-Neoral and orlistat [J ] . Am J Kidney Dis , 2003 , 41 ( 2 ): 493 - 496 .
Colman E , Fossler M . Reduction in blood cyclosporine concentrations by orlistat [J ] . N Engl J Med , 2000 , 342 ( 15 ): 1141 - 1142 .
Knudsen LB , Lau J . The discovery and development of liraglutide and semaglutide [J ] . Front Endocrinol(Lausanne) , 2019 , 10 : 155 .
Gabery S , Salinas CG , Paulsen SJ , et al . Semaglutide lowers body weight in rodents via distributed neural pathways [J ] . JCI Insight , 2020 , 5 ( 6 ): e133429 .
Farr OM , Tsoukas MA , Triantafyllou G , et al . Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues:a randomized,placebo-controlled,crossover study [J ] . Metabolism , 2016 , 65 ( 7 ): 945 - 953 .
Farr OM , Upadhyay J , Rutagengwa C , et al . Longer-term liraglutide administration at the highest dose approved for obesity increases reward-related orbitofrontal cortex activation in response to food cues:Implications for plateauing weight loss in response to anti-obesity therapies [J ] . Diabetes Obes Metab , 2019 , 21 ( 11 ): 2459 - 2464 .
Ard J , Fitch A , Fruh S , et al . Weight loss and maintenance related to the mechanism of action of glucagon-like peptide 1 receptor agonists [J ] . Adv Ther , 2021 , 38 ( 6 ): 2821 - 2839 .
Jepsen MM , Christensen MB . Emerging glucagon-like peptide 1 receptor agonists for the treatment of obesity [J ] . Expert Opin Emerg Drugs , 2021 , 26 ( 3 ): 231 - 243 .
Tak YJ , Lee SY . Long-term efficacy and safety of anti-obesity treatment:where do we stand? [J ] . Curr Obes Rep , 2021 , 10 ( 1 ): 14 - 30 .
Idorn T , Knop FK , Jørgensen MB , et al . Safety and efficacy of liraglutide in patients with type 2 diabetes and end-stage renal disease:an investigator-initiated,placebo-controlled,double-blind,parallel-group,randomized trial [J ] . Diabetes Care , 2016 , 39 ( 2 ): 206 - 213 .
Hiramatsu T , Ozeki A , Asai K , et al . Liraglutide improves glycemic and blood pressure control and ameliorates progression of left ventricular hypertrophy in patients with type 2 diabetes mellitus on peritoneal dialysis [J ] . Ther Apher Dial , 2015 , 19 ( 6 ): 598 - 605 .
Wallace R , Hamblin PS , Tully E , et al . Case report of the successful use of semaglutide to achieve target BMI prior to renal transplant in two patients with end-stage-kidney-disease [J ] . Nephrology(Carlton) , 2024 , 29 ( 6 ): 371 - 374 .
Liou JH , Liu YM , Chen CH . Management of diabetes mellitus with glucagonlike peptide-1 agonist liraglutide in renal transplant recipients:a retrospective study [J ] . Transplant Proc , 2018 , 50 ( 8 ): 2502 - 2505 .
Richardson SH , Wong G , Garner E , et al . Utility of glucagon-like peptide 1 receptor agonists as anti-obesity medications in liver transplant recipients [J ] . Liver Transpl , 2024 , 30 ( 2 ): 226 - 228 .
Chow KW , Ibrahim B , Rahal K , et al . Semaglutide is effective in achieving weight loss in liver transplant recipients [J ] . Liver Transpl , 2024 , 30 ( 2 ): 223 - 225 .
Donald EM , Driggin E , Choe J , et al . Cardio-renal-metabolic outcomes associated with the use of GLP-1 receptor agonists after heart transplantation [J ] . Clin Transplant , 2024 , 38 ( 7 ): e15401 .
Singh P , Pesavento TE , Washburn K , et al . Largest single-centre experience of dulaglutide for management of diabetes mellitus in solid organ transplant recipients [J ] . Diabetes Obes Metab , 2019 , 21 ( 4 ): 1061 - 1065 .
Thangavelu T , Lyden E , Shivaswamy V . A retrospective study of glucagon-like peptide 1 receptor agonists for the management of diabetes after transplantation [J ] . Diabetes Ther , 2020 , 11 ( 4 ): 987 - 994 .
Sodhi M , Rezaeianzadeh R , Kezouh A , et al . Risk of gastrointestinal adverse events associated with glucagon-like peptide-1 receptor agonists for weight loss [J ] . JAMA , 2023 , 330 ( 18 ): 1795 - 1797 .
Wei JJ , Wang RX , Ye HW , et al . Effects of GLP-1 receptor agonists on arrhythmias and its subtypes in patients with type 2 diabetes:a systematic review and meta-analysis [J ] . Front Endocrinol(Lausanne) , 2022 , 13 : 910256 .
Tagliapietra GA , Cantrell MA , Lund BC . Glucagon-like peptide receptor agonists and risk for depression [J ] . Prim Care Diabetes , 2024 , 18 ( 4 ): 422 - 426 .
Yilmaz N , Sari R , Suleymanlar G , et al . Effects of different immunosuppressive drugs on incretins in renal transplant patients [J ] . J Natl Med Assoc , 2020 , 112 ( 3 ): 250 - 257 .
Nauck MA , Meier JJ . GIP and GLP-1:stepsiblings rather than monozygotic twins within the incretin family [J ] . Diabetes , 2019 , 68 ( 5 ): 897 - 900 .
Varol C , Zvibel I , Spektor L , et al . Long-acting glucose-dependent insulinotropic polypeptide ameliorates obesity-induced adipose tissue inflammation [J ] . J Immunol , 2014 , 193 ( 8 ): 4002 - 4009 .
顾 楠 , 黄 佳 , 马晓伟 , 等 . 中国2型糖尿病人群葡萄糖依赖性促胰岛素肽受体基因多态性与冠心病风险的相关性研究 [J ] . 中国糖尿病杂志 , 2017 , 25 ( 3 ): 193 - 198 .
Gu N , Huang J , Ma XW , et al . Association of genetic variability in glucose-dependent insulinotropic polypeptide receptor and coronary artery disease in Chinese Han type 2 diabetic patients [J ] . Chin J Diabetes , 2017 , 25 ( 3 ): 193 - 198 .
Khan R , Tomas A , Rutter GA . Effects on pancreatic Beta and other Islet cells of the glucose-dependent insulinotropic polypeptide [J ] . Peptides , 2020 , 125 : 170201 .
Capozzi ME , D’Alessio DA , Campbell JE . The past,present,and future physiology and pharmacology of glucagon [J ] . Cell Metab , 2022 , 34 ( 11 ): 1654 - 1674 .
Mima A , Horii Y . Tirzepatide reduces fat mass and provides good glycaemic control in type 2 diabetes patients undergoing haemodialysis:a single-centre retrospective study [J ] . Endocrinol Diabetes Metab , 2024 , 7 ( 3 ): e489 .
Dowlatshahi S , Patham B , Kansara A , et al . 13-PUB: safety and efficacy of tirzepatide in patients with solid-organ transplant [EB/OL ] . [ 2025-05-12 ] . https://diabetesjournals.org/diabetes/article/73/Supplement_1/13-PUB/156124/13-PUB-Safety-and-Efficacy-of-Tirzepatide-in https://diabetesjournals.org/diabetes/article/73/Supplement_1/13-PUB/156124/13-PUB-Safety-and-Efficacy-of-Tirzepatide-in .
Yau K , Kuah R , Cherney DZI , et al . Obesity and the kidney:mechanistic links and therapeutic advances [J ] . Nat Rev Endocrinol , 2024 , 20 ( 6 ): 321 - 335 .
Chewcharat A , Prasitlumkum N , Thongprayoon C , et al . Efficacy and safety of SGLT-2 inhibitors for treatment of diabetes mellitus among kidney transplant patients:a systematic review and meta-analysis [J ] . Med Sci (Basel) , 2020 , 8 ( 4 ): 47 .
Halden TAS , Kvitne KE , Midtvedt K , et al . Efficacy and safety of empagliflozin in renal transplant recipients with posttransplant diabetes mellitus [J ] . Diabetes Care , 2019 , 42 ( 6 ): 1067 - 1074 .
Sánchez Fructuoso AI , Raba AB , Deras EB , et al . Sodium-glucose cotransporter-2 inhibitor therapy in kidney transplant patients with type 2 or post-transplant diabetes:an observational multicentre study [J ] . Clin Kidney J , 2023 , 16 ( 6 ): 1022 - 1034 .
Atthota S , Joyal K , Cote M , et al . Modern glucose-lowering drugs in liver transplant recipients:improvement in weight,glycemic control,and potentially allograft steatosis [J ] . Front Transplant , 2023 , 2 : 1223169 .
Cehic MG , Muir CA , Greenfield JR , et al . Efficacy and safety of empagliflozin in the management of diabetes mellitus in heart transplant recipients [J ] . Transplant Direct , 2019 , 5 ( 5 ): e450 .
Sweiss H , Selznick L , Contreras J , et al . Safety and efficacy of sodium-glucose cotransporter-2 inhibitors in solid organ transplant recipients [J ] . Prog Transplant , 2023 , 33 ( 3 ): 261 - 265 .
AlKindi F , Al-Omary HL , Hussain Q , et al . Outcomes of SGLT2 inhibitors use in diabetic renal transplant patients [J ] . Transplant Proc , 2020 , 52 ( 1 ): 175 - 178 .
Kanbay M , Demiray A , Afsar B , et al . Sodium-glucose cotransporter 2 inhibitors for diabetes mellitus control after kidney transplantation:Review of the current evidence [J ] . Nephrology(Carlton) , 2021 , 26 ( 12 ): 1007 - 1017 .
Lawrence SE , Chandran MM , Park JM , et al . Sweet and simple as syrup:a review and guidance for use of novel antihyperglycemic agents for post-transplant diabetes mellitus and type 2 diabetes mellitus after kidney transplantation [J ] . Clin Transplant , 2023 , 37 ( 3 ): e14922 .
Courcoulas AP , Daigle CR , Arterburn DE . Long term outcomes of metabolic/bariatric surgery in adults [J ] . BMJ , 2023 , 383 : e071027 .
Yemini R , Nesher E , Carmeli I , et al . Bariatric surgery is efficacious and improves access to transplantation for morbidly obese renal transplant candidates [J ] . Obes Surg , 2019 , 29 ( 8 ): 2373 - 2380 .
Al-Bahri S , Fakhry TK , Gonzalvo JP , et al . Bariatric surgery as a bridge to renal transplantation in patients with end-stage renal disease [J ] . Obes Surg , 2017 , 27 ( 11 ): 2951 - 2955 .
Fernando S , Varma J , Dengu F , et al . Bariatric surgery improves access to renal transplantation and is safe in renal failure as well as after transplantation:a systematic review and meta-analysis [J ] . Transplant Rev (Orlando) , 2023 , 37 ( 3 ): 100777 .
Sheetz KH , Gerhardinger L , Dimick JB , et al . Bariatric surgery and long-term survival in patients with obesity and end-stage kidney disease [J ] . JAMA Surg , 2020 , 155 ( 7 ): 581 - 588 .
Spaggiari M , Di Cocco P , Tulla K , et al . Simultaneous robotic kidney transplantation and bariatric surgery for morbidly obese patients with end-stage renal failure [J ] . Am J Transplant , 2021 , 21 ( 4 ): 1525 - 1534 .
Schindel H , Winkler J , Yemini R , et al . Survival benefit in bariatric surgery kidney recipients may be mediated through effects on kidney graft function and improvement of co-morbidities:a case-control study [J ] . Surg Obes Relat Dis , 2019 , 15 ( 4 ): 621 - 627 .
Lin MYC , Tavakol MM , Sarin A , et al . Laparoscopic sleeve gastrectomy is safe and efficacious for pretransplant candidates [J ] . Surg Obes Relat Dis , 2013 , 9 ( 5 ): 653 - 658 .
Heimbach JK , Watt KS , Poterucha JJ , et al . Combined liver transplantation and gastric sleeve resection for patients with medically complicated obesity and end-stage liver disease [J ] . Am J Transplant , 2013 , 13 ( 2 ): 363 - 368 .
Lin MYC , Tavakol MM , Sarin A , et al . Safety and feasibility of sleeve gastrectomy in morbidly obese patients following liver transplantation [J ] . Surg Endosc , 2013 , 27 ( 1 ): 81 - 85 .
Lee Y , Anvari S , Sam Soon M , et al . Bariatric surgery as a bridge to heart transplantation in morbidly obese patients:a systematic review and meta-analysis [J ] . Cardiol Rev , 2022 , 30 ( 1 ): 1 - 7 .
Tsamalaidze L , Elli EF . Bariatric surgery is Gaining ground as treatment of obesity after heart transplantation:report of two cases [J ] . Obes Surg , 2017 , 27 ( 11 ): 3064 - 3067 .
El Moussaoui I , De Pauw V , Navez J , et al . Roux-En-Y gastric bypass after lung transplantation:case report and literature review [J ] . Surg Obes Relat Dis , 2021 , 17 ( 1 ): 239 - 241 .
Castillo-Larios R , Gunturu NS , Elli EF . Outcomes of bariatric surgery before,during,and after solid organ transplantation [J ] . Obes Surg , 2022 , 32 ( 12 ): 3821 - 3829 .
Cohen JB , Lim MA , Tewksbury CM , et al . Bariatric surgery before and after kidney transplantation:long-term weight loss and allograft outcomes [J ] . Surg Obes Relat Dis , 2019 , 15 ( 6 ): 935 - 941 .
Onghena L , Geerts A , Berrevoet F , et al . Bariatric surgery post-liver transplantation:a Belgian nationwide study [J ] . Liver Transpl , 2024 , 30 ( 10 ): 1050 - 1057 .
Tsamalaidze L , Stauffer JA , Arasi LC , et al . Laparoscopic sleeve gastrectomy for morbid obesity in patients after orthotopic liver transplant:a matched case-control study [J ] . Obes Surg , 2018 , 28 ( 2 ): 444 - 450 .
Perdomo CM , Cohen RV , Sumithran P , et al . Contemporary medical,device,and surgical therapies for obesity in adults [J ] . Lancet , 2023 , 401 ( 10382 ): 1116 - 1130 .
Trastulli S , Desiderio J , Guarino S , et al . Laparoscopic sleeve gastrectomy compared with other bariatric surgical procedures:a systematic review of randomized trials [J ] . Surg Obes Relat Dis , 2013 , 9 ( 5 ): 816 - 829 .
Golomb I , Winkler J , Ben-Yakov A , et al . Laparoscopic sleeve gastrectomy as a weight reduction strategy in obese patients after kidney transplantation [J ] . Am J Transplant , 2014 , 14 ( 10 ): 2384 - 2390 .
Viscido G , Gorodner V , Signorini FJ , et al . Sleeve gastrectomy after renal transplantation [J ] . Obes Surg , 2018 , 28 ( 6 ): 1587 - 1594 .
Cheng YL , Elli EF . Outcomes of bariatric surgery after solid organ transplantation [J ] . Obes Surg , 2020 , 30 ( 12 ): 4899 - 4904 .
Fagenson AM , Mazzei M , Swaszek L , et al . Is bariatric procedure type associated with morbidity in transplant patients? [J ] . J Surg Res , 2022 , 273 : 172 - 180 .
Verhoeff K , Dang JT , Modasi A , et al . Bariatric surgery outcomes in patients with previous organ transplant:scoping review and analysis of the MBSAQIP [J ] . Obes Surg , 2021 , 31 ( 2 ): 508 - 516 .
Suraweera D , Dutson E , Saab S . Liver transplantation and bariatric surgery:best approach [J ] . Clin Liver Dis , 2017 , 21 ( 2 ): 215 - 230 .
Vu L , Switzer NJ , De Gara C , et al . Surgical interventions for obesity and metabolic disease [J ] . Best Pract Res Clin Endocrinol Metab , 2013 , 27 ( 2 ): 239 - 246 .
D’Ovidio F , Keshavjee S . Gastroesophageal reflux and lung transplantation [J ] . Dis Esophagus , 2006 , 19 ( 5 ): 315 - 320 .
Li B , Hartwig MG , Appel JZ , et al . Chronic aspiration of gastric fluid induces the development of obliterative bronchiolitis in rat lung transplants [J ] . Am J Transplant , 2008 , 8 ( 8 ): 1614 - 1621 .
Yeung KTD , Penney N , Ashrafian L , et al . Does sleeve gastrectomy expose the distal esophagus to severe reflux? a systematic review and meta-analysis [J ] . Ann Surg , 2020 , 271 ( 2 ): 257 - 265 .
Lanthaler M , Aigner F , Kinzl J , et al . Long-term results and complications following adjustable gastric banding [J ] . Obes Surg , 2010 , 20 ( 8 ): 1078 - 1085 .
Mittermair RP , Obermüller S , Perathoner A , et al . Results and complications after Swedish adjustable gastric banding-10 years experience [J ] . Obes Surg , 2009 , 19 ( 12 ): 1636 - 1641 .
Spivak H , Abdelmelek MF , Beltran OR , et al . Long-term outcomes of laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass in the United States [J ] . Surg Endosc , 2012 , 26 ( 7 ): 1909 - 1919 .
Tran TT , Pauli E , Lyn-Sue JR , et al . Revisional weight loss surgery after failed laparoscopic gastric banding:an institutional experience [J ] . Surg Endosc , 2013 , 27 ( 11 ): 4087 - 4093 .
Fagenson AM , Mazzei M , Edwards MA . Does steroid use in transplant patients undergoing bariatric surgery independently impact outcomes? [J ] . J Surg Res , 2020 , 254 : 294 - 299 .
Lee Y , Raveendran L , Lovrics O , et al . The role of bariatric surgery on kidney transplantation:a systematic review and meta-analysis [J ] . Can Urol Assoc J , 2021 , 15 ( 10 ): E553 - E562 .
Zaminpeyma R , Claus M , Paraskevas S , et al . Outcomes of kidney transplant recipients who underwent pre-transplant bariatric surgery for severe obesity:a long-term follow-up study [J ] . Surg Endosc , 2023 , 37 ( 1 ): 494 - 502 .
Yemini R , Nesher E , Winkler J , et al . Bariatric surgery in solid organ transplant patients:Long-term follow-up results of outcome,safety,and effect on immunosuppression [J ] . Am J Transplant , 2018 , 18 ( 11 ): 2772 - 2780 .
Diwan TS , Lee TC , Nagai SJ , et al . Obesity,transplantation,and bariatric surgery:an evolving solution for a growing epidemic [J ] . Am J Transplant , 2020 , 20 ( 8 ): 2143 - 2155 .
Gazzetta PG , Bissolati M , Saibene A , et al . Bariatric surgery to target obesity in the renal transplant population:preliminary experience in a single center [J ] . Transplant Proc , 2017 , 49 ( 4 ): 646 - 649 .
Osseis M , Lazzati A , Salloum C , et al . Sleeve gastrectomy after liver transplantation:feasibility and outcomes [J ] . Obes Surg , 2018 , 28 ( 1 ): 242 - 248 .
Chan G , Hajjar R , Boutin L , et al . Prospective study of the changes in pharmacokinetics of immunosuppressive medications after laparoscopic sleeve gastrectomy [J ] . Am J Transplant , 2020 , 20 ( 2 ): 582 - 588 .
Srinivas NR . Impact of roux-en-Y gastric bypass surgery on pharmacokinetics of administered drugs:implications and perspectives [J ] . Am J Ther , 2016 , 23 ( 6 ): e1826 - e1838 .
Rogers CC , Alloway RR , Alexander JW , et al . Pharmacokinetics of mycophenolic acid,tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients:a pilot study [J ] . Clin Transplant , 2008 , 22 ( 3 ): 281 - 291 .
中华医学会器官移植学分会 , 中国医疗保健国际交流促进会肾脏移植学分会 . 中国肾脏移植长期健康管理指南(2023版) [J ] . 中华器官移植杂志 , 2024 , 45 ( 5 ): 283 - 298 .
Chinese Society of Organ Transplantation , Renal Transplantation Branch of China International Exchange and Promotive Association for Medical and Health Care . Guideline for long-term health management of kidney transplantation in China(2023 edition) [J ] . Chin J Organ Transplant , 2024 , 45 ( 5 ): 283 - 298 .
中国医师协会外科医师分会肥胖和糖尿病外科医师委员会 . 精准肥胖代谢外科手术中国专家共识(2022版) [J ] . 中华消化外科杂志 , 2022 , 21 ( 10 ): 1302 - 1312 .
Bariatric and Metabolic Surgeon Committee of Chinese College of Surgeons . Chinese expert consensus on precision bariatric and metabolic surgery (2022 edition) [J ] . Chin J Dig Surg , 2022 , 21 ( 10 ): 1302 - 1312 .
中华医学会内分泌学分会 , 中华中医药学会糖尿病分会 , 中国医师协会外科医师分会肥胖和糖尿病外科医师委员会 , 等 . 基于临床的肥胖症多学科诊疗共识(2021年版) [J ] . 中华内分泌代谢杂志 , 2021 , 37 ( 11 ): 959 - 972 .
Chinese Society of Endocrinology , Diabetes Branch of Chinese Traditional Medicine Association , Bariatric and Metabolic Surgeon Committee of Chinese College of Surgeons , et al . Multidisciplinary diagnosis and treatment consensus for obesity based on clinical practice(2021 edition) [J ] . Chin J Endocrinol Metab , 2021 , 37 ( 11 ): 959 - 972 .
Bal BS , Finelli FC , Shope TR , et al . Nutritional deficiencies after bariatric surgery [J ] . Nat Rev Endocrinol , 2012 , 8 ( 9 ): 544 - 556 .
0
Views
9
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621
