Value of voice recognition function test in cognitive function screening among elderly patients

Liu Junjin; Chen Yingxi; Lü Yang

doi:10.13406/j.cnki.cyxb.003825

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Value of voice recognition function test in cognitive function screening among elderly patients

Frontiers in brain science and neuropsychiatric disorders | 更新时间：2025-10-22

- Value of voice recognition function test in cognitive function screening among elderly patients
- Journal of Chongqing Medical University Vol. 50, Issue 6, Pages: 785-790(2025)
- 作者机构：
  
  1.重庆医科大学附属第一医院老年科，重庆 400016
  2.重庆医科大学基础医学院神经科学研究所解剖教研室，重庆 400016
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.003825
  CLC： R592
- Received：03 December 2024，
  
  Revised：2025-01-14，
  
  Accepted：23 January 2025，
  
  Published：28 June 2025
- 稿件说明：
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刘峻金,陈映汐,吕洋.声音识别测试对老年患者认知功能筛查的研究[J].重庆医科大学学报,2025,50(6):785-790.

Liu Junjin,Chen Yingxi,Lü Yang.Value of voice recognition function test in cognitive function screening among elderly patients[J].Journal of Chongqing Medical University,2025,50(6):785-790.
刘峻金,陈映汐,吕洋.声音识别测试对老年患者认知功能筛查的研究[J].重庆医科大学学报,2025,50(6):785-790. DOI： 10.13406/j.cnki.cyxb.003825.

Liu Junjin,Chen Yingxi,Lü Yang.Value of voice recognition function test in cognitive function screening among elderly patients[J].Journal of Chongqing Medical University,2025,50(6):785-790. DOI： 10.13406/j.cnki.cyxb.003825.

摘要

目的

探讨声音识别功能在痴呆早期筛查中的应用价值。

方法

本研究共纳入170例老年人，其中认知功能受损者55例（A组，

=55），认知功能正常者115例（B组，

=115）。通过简易智力状态检查（mini-mental state examination，MMSE）判断受试者是否存在认知功能受损，再通过设计的声音基本辨别和名人声音辨认2种题目，判断受试者是否存在声音识别功能减退，来分析声音识别功能和认知功能间的关系。

结果

声音基本辨别题目正确数：A组低于B组，差异有统计学意义（

0.001）。名人声音辨认题目正确数：A组低于B组，差异有统计学意义（

0.001）。通过受试者工作特征曲线下面积（area under the receiver operating characteristic curve，AUROC）分析，认知功能与声音基本辨别测试题的相关性为0.180（95%CI=0.108~0.253），认知功能与名人声音辨认测试题的相关性为AUROC=0.139（95%CI=0.079~0.199），差异均有统计学意义。声音识别功能测试用于初筛，在保障阴性预测值约90%的前提下，声音基本辨别测试题的分界值为10题（共12题），名人声音辨认测试题为7题（共12题）。

结论

认知功能受损老年人和正常老年人，在声音基本辨别和名人声音辨认测试题的表现均具有明显统计学差异，提示声音识别测试可用于早期痴呆患者的筛查，延缓病情进展和减轻医疗负担。

Abstract

Objective

To investigate the value of voice recognition function in the early screening of dementia.

Methods

A total of 55 elderly individuals with cognitive function impairment were enrolled as group A，and 115 normal elderly individuals were enrolled as group B. Mini-mental state examination（MMSE） was used to determine the presence or absence of cognitive function impairment，and then the two questions of basic voice discrimination and celebrity voice recognition were designed to determine whether there was a decline in voice recognition function and analyze the association between voice recognition function and cognitive function.

Results

The correct number of basic sound discrimination questions：Group A was lower than group B（

0.001），and the difference was statistically significant. The correct number of celebrity voice recognition questions：Group A was lower than group B（

0.001），and the difference was statistically significant. The AUROC analysis showed that the correlation between cognitive function and basic voice discrimination test was 0.180（95%CI=0.108-0.253），and the correlation between cognitive function and celebrity voice recognition test was AUROC=0.139（95%CI=0.079-0.199），both of which showed statistical significance. The voice recognition function test was used for preliminary screening，and under the premise of ensuring a negative predictive value of about 90%，the basic voice discrimination test had a cut-off value of 10 questions（12 questions in total），and the celebrity voice recognition test had a cut-off value of 7 questions（12 questions in total）.

Conclusion

There are significant differences in the performance for basic voice discrimination test and celebrity voice recognition test between the elderly patients with cognitive function impairment and the normal elderly individuals，suggesting that voice recognition function test can be used for the screening for patients with early dementia，thereby delaying disease progression and reducing medical burden.

关键词

Keywords

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