Efficacy and safety of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm
Efficacy and safety of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm
Journal of Chongqing Medical UniversityVol. 50, Issue 4, Pages: 444-448(2025)
Huang Guohua,Su Shuai,Zhang Jindong,et al.Efficacy and safety of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm[J].Journal of Chongqing Medical University,2025,50(4):444-448.
Huang Guohua,Su Shuai,Zhang Jindong,et al.Efficacy and safety of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm[J].Journal of Chongqing Medical University,2025,50(4):444-448. DOI: 10.13406/j.cnki.cyxb.003793.
Efficacy and safety of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm
2组患者年龄、体质指数(body mass index,BMI)、性别、既往结石手术史、结石患侧、结石最大经、术前C反应蛋白、集合系统分离、术前结石CT值和结石部位等术前一般资料对比差异无统计学意义。试验组的手术时长为(44.94±52.60) min低于对照组的(52.60±14.22) min,差异有统计学意义(
To investigate the safety and feasibility of one-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent in the treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm.
Methods
2
A total of 70 patients with upper ureteral calculi or renal calculi with a long diameter of ≤10 mm who were admitted to Guang’an Hospital,West China Hospital of Sichuan University,from January 2023 to June 2024 were enrolled and randomly divided into experimental group (without ureteral access sheath or ureteral stent) and control group (with ureteral access sheath and ureteral stent),with 35 patients in each group. The patients in the experimental group did not use a ureteral access sheath or a ureteral stent,while those in the control group used the ureteral access sheath and the ureteral stent. The two groups were compared in terms of preoperative data,intraoperative complications,stone clearance rate,length of hospital stay,hospital costs,and postoperative complications.
Results
2
There were no significant differences between the two groups in preoperative data such as age,body mass index,sex,previous history of stone surgery,affected side,maximum stone diameter,C-reactive protein,aggregation system separation,preoperative CT value of stones,and stone location. The experimental group had a significantly shorter time of operation than the control group[(44.94±52.60) minutes vs. (52.60±14.22) minutes,
t
=2.240,
P
=0
.030]. There were no significant differences between the two groups in intraoperative data such as ureteral injury,intraoperative leukocyte changes,and intraoperative blood loss. The experimental group had significantly lower hospital costs than the control group[(8041.89±1287.57) yuan vs. (13 011.63±1 780.21) yuan,
t
=13.450,
P
=0.000]. There were no significant differences between the experimental group and the control group in the postoperative data such as the length of hospital stay,the recurrence of calculi on CT at 1 and 3 months after surgery,stone clearance rate,postoperative urinary tract irritation,postoperative ureteral injury,postoperative hematuria,and postoperative hydronephrosis(
P
>
0.05).
Conclusion
2
One-stage flexible ureteroscopic lithotripsy without ureteral access sheath or ureteral stent is safe and feasible in the treatment of upper ureteral calculi and renal calculi with a long diameter of ≤10 mm and can effectively reduce hospital costs and time of operation.
Chinese expert consensus on metabolic evaluation and recurrence prevention ofurolithiasis [J ] . Chin J Urol , 2023 , 44 ( 5 ): 321 - 324 .
Zhu W , Liu Y , Lan Y , et al . Dietary vinegar prevents kidney stone recurrence via epigenetic regulations [J ] . EBioMedicine , 2019 , 45 : 231 - 250 .
Bagley DH , Huffman JL , Lyon ES . Flexible ureteropyeloscopy:diagnosis and treatment in the upper urinary tract [J ] . J Urol , 1987 , 138 ( 2 ): 280 - 285 .
Doizi S , Traxer O . Flexible ureteroscopy:technique,tips and tricks [J ] . Urolithiasis , 2018 , 46 ( 1 ): 47 - 58 .
Geraghty RM , Davis NF , Tzelves L , et al . Best practice in interventional management of urolithiasis:an update from the European association of urology guidelines panel for urolithiasis 2022 [J ] . Eur Urol Focus , 2023 , 9 ( 1 ): 199 - 208 .
He M , Dong Y , Cai W , et al . Recent advances in the treatment of renal stones using flexible ureteroscopys [J ] . Int J Surg , 2024 , 110 ( 7 ): 4320 - 4328 .
Zeng G , Traxer O , Zhong W , et al . International Alliance of Urolithiasis guideline on retrograde intrarenal surgery [J ] . BJU Int , 2023 , 131 ( 2 ): 153 - 164 .
Proietti S , Knoll T , Giusti G . Contemporary ureteroscopic management of renal stones [J ] . Int J Surg , 2016 , 36 ( 4 ): 681 - 687 .
Kaplan AG , Lipkin ME , Scales CD , et al . Use of ureteral access sheaths in ureteroscopy [J ] . Nat Rev Urol , 2016 , 13 ( 3 ): 135 - 140 .
L’esperance JO , Ekeruo WO , Scales CD , et al . Effect of ureteral access sheath on stone-free rates in patients undergoing ureteroscopic management of renal calculi [J ] . Urology , 2005 , 66 ( 2 ): 252 - 255 .
Traxer O , Wendt-Nordahl G , Sodha H , et al . Differences in renal stone treatment and outcomes for patients treated either with or without the support of a ureteral access sheath:The Clinical Research Office of the Endourological Society Ureteroscopy Global Study [J ] . World J Urol , 2015 , 33 ( 12 ): 2137 - 2144 .
Berquet G , Prunel P , Verhoest G , et al . The use of a ureteral access sheath does not improve stone-free rate after ureteroscopy for upper urinary tract stones [J ] . World J Urol , 2014 , 32 ( 1 ): 229 - 232 .
Haleblian G , Kijvikai K , de la Rosette J , et al . Ureteral stenting and urinary stone management:a systematic review [J ] . J Urol , 2008 , 179 ( 2 ): 424 - 430 .
Nabi G , Cook J , N’Dow J , et al . Outcomes of stenting after uncomplicated ureteroscopy:systematic review and meta-analysis [J ] . BMJ , 2007 , 334 ( 7593 ): 572 .
Bosio A , Alessandria E , Dalmasso E , et al . How bothersome double-J ureteral stents are after semirigid and flexible ureteroscopy:a prospective single-institution observational study [J ] . World J Urol , 2019 , 37 ( 1 ): 201 - 207 .
Zhou ZJ , Wu Z . Development status and future prospects of flexible ureteroscopy technology [J ] . Journal of Clinical Urology , 2023 , 38 ( 7 ): 553 - 556,561 .
Srisubat A , Potisat S , Lojanapiwat B , et al . Extracorporeal shock wave lithotripsy(ESWL) versus percutaneous nephrolithotomy(PCNL) or retrograde intrarenal surgery(RIRS) for kidney stones [J ] . Cochrane Database Syst Rev , 2009 (4):CD007044.
Asutay MK , Lattarulo M , Liourdi D , et al . Does ureteral access sheath have an impact on ureteral injury? [J ] . Urol Ann , 2022 , 14 ( 1 ): 1 - 7 .
Huang J , Zhao Z , AlSmadi JK , et al . Use of the ureteral access sheath during ureteroscopy:a systematic review and meta-analysis [J ] . PLoS One , 2018 , 13 ( 2 ): e0193600 .
Zeng GH , Zhao ZJ , Mazzon G , et al . European association of urology section of urolithiasis and international alliance of urolithiasis joint consensus on retrograde intrarenal surgery for the management of renal stones [J ] . Eur Urol Focus , 2022 , 8 ( 5 ): 1461 - 1468 .
Tomer N , Garden E , Small A , et al . Ureteral stent encrustation:epidemiology,pathophysiology,management and current technology [J ] . J Urol , 2021 , 205 ( 1 ): 68 - 77 .
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