1.重庆医科大学附属第一医院,泌尿外科
2.手术室
3.护理部,重庆 400016
Received:15 March 2024,
Revised:2024-05-16,
Accepted:23 May 2024,
Published:28 June 2024
移动端阅览
罗义佳,李跃荣,任洪艳.基于HALF分级的上尿路结石围手术期感染预防和管理的应用研究[J].重庆医科大学学报,2024,49(6):791-796.
Luo Yijia,Li Yuerong,Ren Hongyan.Perioperative infection prevention and management for upper urolithiasis based on HALF grouping[J].Journal of Chongqing Medical University,2024,49(6):791-796.
罗义佳,李跃荣,任洪艳.基于HALF分级的上尿路结石围手术期感染预防和管理的应用研究[J].重庆医科大学学报,2024,49(6):791-796. DOI: 10.13406/j.cnki.cyxb.003511.
Luo Yijia,Li Yuerong,Ren Hongyan.Perioperative infection prevention and management for upper urolithiasis based on HALF grouping[J].Journal of Chongqing Medical University,2024,49(6):791-796. DOI: 10.13406/j.cnki.cyxb.003511.
目的
2
评价基于HALF(高风险high risk,H;无症状菌尿asymptomatic bacteriuria,A;低风险low risk,L;发热fever,F)分级的医护协作管理在改善上尿路结石围术期感染预防和治疗的效果。
方法
2
检索证据,形成以分级管理、尿脓毒症筛查和1 h集束化管理为主的方案。采用非同期前后对照研究,以重庆医科大学附属第一医院2023年1至12月收治的上尿路结石患者为干预组(
n
=2 142),实施以HALF分组为基础的围术期预防和管理;2022年1至12月的病例为对照组(
n
=1 938),实施常规管理。比较2组患者抗菌药疗程合理率、全身炎症反应综合征检出率、脓毒症发生率等。
结果
2
与对照组相比,干预组抗菌药术前使用疗程合理率提高(60.99% vs. 76.24%,
P
=0.000),术后疗程合理率提高(76.62% vs. 83.94%,
P
=0.000);全身炎症反应综合征检出率提高(5.21% vs. 6.91%,
P
=0.024),术后脓毒症发生率下降(0.98% vs. 0.42%,
P
=0.030),脓毒症抗菌药物使用窗口期缩短[(57.45±17.32) min vs.(50.90±16.08) min,
P
=0.039],差异有统计学意义(
P
<
0.05)。
结论
2
基于HALF分级的医护协作管理能改善上尿路结石的围术期感染预防和治疗效果,值得推广。
Objective
2
To evaluate the effectiveness of doctor-nurse collaboration management based on HALF(high risk,asymptomatic bacteriuria,low risk,fever) grouping in improving perioperative infection prevention and treatment of upper urolithiasis.
Methods
2
Evidence was retrieved to form the plan mainly composed of grouping management,the screening for urinary sepsis,and 1-hour management bundle. A controlled before-and-after study was implemented. The patients with upper urolithiasis admitted in January to December 2023 were included in intervention group(
n
=2 142) and received perioperative infection prevention and management based on HALF grouping. The patients admitted in January to December 2022(
n
=1 938) were included in control group and received conventional management. The rate of rational antibiotic treatment course,detection rate of systemic inflammatory response syndrome,and incidence of sepsis were compared between the two groups.
Results
2
Compared with the control group,the intervention group showed significantly higher rates of rational antibiotic treatment course before operation(60.99% vs. 76.24%,
P
=0.000) and after operation(76.62% vs. 83.94%,
P
=0.000),a significantly higher detection rate of systemic inflammatory response syndrome (5.21% vs. 6.91%,
P
=0.024),a significantly lower postoperative incidence of sepsis(0.98% vs. 0.42%,
P
=0.030),and a significantly narrower window of antibiotic use for sepsis[(57.45±17.32) min vs. (50.90±16.08) min,
P
=0.039] (
P
<
0.05).
Conclusion
2
The doctor-nurse collaboration management based on HALF grouping can improve the quality of perioperative infection prevention and treatment in upper urolithiasis,and is worth promoting.
Tan SS , Yuan DB , Su H , et al . Prevalence of urolithiasis in China:a systematic review and meta-analysis [J ] . BJU Int , 2024 , 133 ( 1 ): 34 - 43 .
Chugh S , Pietropaolo A , Montanari E , et al . Predictors of urinary infections and urosepsis after ureteroscopy for stone disease:a systematic review from EAU section of urolithiasis(EULIS) [J ] . Curr Urol Rep , 2020 , 21 ( 4 ): 16 .
康家旗 , 杨永姣 , 刘 莉 , 等 . 输尿管结石致尿脓毒血症患者发生严重脓毒症或脓毒性休克的危险因素分析 [J ] . 重庆医科大学学报 , 2018 , 43 ( 4 ): 556 - 559 .
Kang JQ , Yang YJ , Liu L , et al . Risk factors for severe sepsis or septic shock in patients with urosepsis due to ureteral calculi [J ] . J Chongqing Med Univ , 2018 , 43 ( 4 ): 556 - 559 .
Wagenius M , Borglin J , Popiolek M , et al . Percutaneous nephrolithotomy and modern aspects of complications and antibiotic treatment [J ] . Scand J Urol , 2020 , 54 ( 2 ): 162 - 170 .
上尿路结石围手术期感染控制及抗菌药物应用专家意见编写组 . 上尿路结石患者围手术期感染控制及抗菌药物应用专家意见(2023版) [J ] . 中华泌尿外科杂志 , 2023 , 44 ( 7 ): 481 - 485 .
Expert opinion writing group on perioperative infection control and antibiotic application for upper urinary tract stones . Expert opinions on perioperative infection control and antibiotic application in patients with upper urinary tract calculi(2023 edition) [J ] . Chin J Urol , 2023 , 44 ( 7 ): 481 - 485 .
黄健 , 张旭 . 中国泌尿外科和男科疾病诊断治疗指南: 2022版 [M ] . 北京 : 科学出版社 , 2022 .
Huang J , Zhang X . Guidelines for diagnosis and treatment of urology and andrology diseases in China:2022 edition [M ] . Beijing : Science Press , 2022 .
Alexander A , Clovis R . Sepsis in adults [DB/OL ] . BMJ Best Practice . ( 2023-01-01 ). https://bestpractice.bmj.com/topics/en-gb/3000098/diagnosis-recommendations https://bestpractice.bmj.com/topics/en-gb/3000098/diagnosis-recommendations .
Gupta K . Acute complicated urinary tract infection(including pyelonephritis) in adults and adolescents [DB/OL ] . UpToDate . ( 2022-09-01 ). https://www.uptodate.cn/contents/zh-Hans/acute-complicated-urinary-tract-infection-including-pyelonephritis-in-adults-and-adolescents?search=urinary%20tract%20infection&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2 https://www.uptodate.cn/contents/zh-Hans/acute-complicated-urinary-tract-infection-including-pyelonephritis-in-adults-and-adolescents?search=urinary%20tract%20infection&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2 .
Evans L , Rhodes A , Alhazzani W , et al . Surviving sepsis campaign:international guidelines for management of sepsis and septic shock 2021 [J ] . Intensive Care Med , 2021 , 47 ( 11 ): 1181 - 1247 .
孙红玲 , 刘丽欢 , 刘春香 , 等 . 尿路结石腔内碎石患者围手术期并发尿脓毒症护理专家共识 [J ] . 中华护理杂志 , 2022 , 57 ( 8 ): 914 - 917 .
Sun HL , Liu LH , Liu CX , et al . Expert consensus on perioperative urosepsis nursing of patients with intracavitary surgery for urinary tract calculi [J ] . Chin J Nurs , 2022 , 57 ( 8 ): 914 - 917 .
Singer M , Deutschman CS , Seymour CW , et al . The third international consensus definitions for sepsis and septic shock (sepsis-3) [J ] . JAMA , 2016 , 315 ( 8 ): 801 - 810 .
王 仲 , 魏 捷 , 朱华栋 , 等 . 中国脓毒症早期预防与阻断急诊专家共识 [J ] . 中国急救医学 , 2020 , 40 ( 7 ): 577 - 588 .
Wang Z , Wei J , Zhu HD , et al . Expert consensus on early prevention and blocking of sepsis in China [J ] . Chin J Crit Care Med , 2020 , 40 ( 7 ): 577 - 588 .
EAU . Urological Infections Guidelines [DB/OL ] . The Netherland:EAU Guidelines Office . ( 2019-06-01 ). https://uroweb.org/guidelines https://uroweb.org/guidelines .
Xie JF , Wang HL , Kang Y , et al . The epidemiology of sepsis in Chinese ICUs : a national cross-sectional survey [J ] . Crit Care Med , 2020 , 48 ( 3 ): e209 - e218 .
Bleakley G , Cole M . Recognition and management of sepsis:the nurse’s role [J ] . Br J Nurs , 2020 , 29 ( 21 ): 1248 - 1251 .
苑喜微 , 南月敏 . 血红素加氧酶1调控铁死亡对非酒精性脂肪性肝病的作用机制研究进展 [J ] . 中华肝脏病杂志 , 2024 , 10 ( 3 ): 262 - 267 .
Yuan XW , Nan YM . Research progress on the mechanism of action of heme oxygenase-1 regulating ferroptosis in non-alcoholic fatty liver disease [J ] . Chin J Hepatol , 2024 , 10 ( 3 ): 262 - 267 .
Fleischmann C , Scherag A , Adhikari NK , et al . Assessment of global incidence and mortality of hospital-treated sepsis. current estimates and limitations [J ] . Am J Respir Crit Care Med , 2016 , 193 ( 3 ): 259 - 272 .
Labib A . Sepsis care pathway 2019 [J ] . Qatar Med J , 2019 , 2019 ( 2 ): 4 .
邓紫薇 , 全科立 , 史志华 , 等 . 基于证据质量评价泌尿结石科围术期抗菌药物用药路径的制定及效果 [J ] . 临床药物治疗杂志 , 2022 , 20 ( 5 ): 50 - 56 .
Deng ZW , Quan KL , Shi ZH , et al . Establishiment and effect of clinical medication route of antibiotics for Urolithiasis Department based on evidence quality evaluation [J ] . Clin Med J , 2022 , 20 ( 5 ): 50 - 56 .
0
Views
4
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621
