Yuan Fang,Wang Gang.Progress in pharmacotherapy for Alzheimer's disease[J].Journal of Chongqing Medical University,2024,49(5):522-525. DOI: 10.13406/j.cnki.cyxb.003505.
Progress in pharmacotherapy for Alzheimer's disease
In recent years,with the development of disease-modifying therapies(DMT) such as monoclonal antibodies against amyloid-beta protein(Aβ),drug treatment for Alzheimer's disease(AD) has entered a new era. Currently,two antibodies targeting Aβ—aducanumab and lecanemab—have been approved for clinical use,attracting widespread attention worldwide. Meanwhile,remarkable progress has also been made in the development of drugs against non-Aβ and non-tau targets. This review highlights the latest advances in the development and application of drugs for AD that have been clinically approved or in clinical trials.
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