Zhang Feng,Yu Xujun,Dong Liang,et al.Initial exploration of multispectral optoacoustic tomography in imaging of the testes in varicocele rats[J].Journal of Chongqing Medical University,2023,48(10):1166-1172.
Zhang Feng,Yu Xujun,Dong Liang,et al.Initial exploration of multispectral optoacoustic tomography in imaging of the testes in varicocele rats[J].Journal of Chongqing Medical University,2023,48(10):1166-1172. DOI: 10.13406/j.cnki.cyxb.003355.
Initial exploration of multispectral optoacoustic tomography in imaging of the testes in varicocele rats
To explore the feasibility of photoacoustic tomography(PAT) and multispectral optoacoustic tomography(MSOT) for testicular structure and function imaging in a varicocele rat model.
Methods
2
Eighteen SD rats were randomly divided into blank group,model group,and Aescuven forte group,with 6 rats in each group. In the model group and Aescuven forte group,a varicocele rat model was established by narrowing the left renal vein and ligating the left spermatic vein. After 4 weeks of intervention,the PAT/MSOT image,oxygen metabolism,and oxidative stress levels of rat left testicle were compared to investigate the testicular imaging characteristics of rats with different interventions.
Results
2
PAT/MSOT provided a clear image of rat testicular structure and reflected the level of oxygen metabolism in the testes.
Conclusion
2
PAT/MSOT can be used to detect the structural and functional changes in the testis caused by varicocele. PAT/MSOT is a novel,simple,and safe method for non-invasive evaluation of testes.
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Department of Urology,the Children’s Hospital,Chongqing Medical University,Ministry of Education Key Laboratory of Child Development and Disorders,Key Laboratory of Pediatrics in Chongqing,Chongqing International Science and Technology Cooperation Center for Child Development and Disorders
Department of Urology,the Second Affiliated Hospital,Chongqing Medical University
重庆医科大学附属第二医院泌尿外科
Department of Urology,the First Affiliated Hospital,Chongqing Medical University