重庆医科大学附属第二医院肿瘤治疗中心,重庆 400030
Received:12 September 2021,
Revised:2022-05-11,
Accepted:15 June 2022,
Published:28 February 2023
移动端阅览
江南,陈星,周崑,等.团块状灰度变化减轻子宫良性疾病聚焦超声消融术中的远场不良反应[J].重庆医科大学学报,2023,48(2):162-166.
Jiang Nan,Chen Xing,Zhou Kun,et al.Massive gray scale change benefits far-field adverse effects during focused ultrasound ablation in the treatment of benign uterine diseases[J].Journal of Chongqing Medical University,2023,48(2):162-166.
江南,陈星,周崑,等.团块状灰度变化减轻子宫良性疾病聚焦超声消融术中的远场不良反应[J].重庆医科大学学报,2023,48(2):162-166. DOI: 10.13406/j.cnki.cyxb.003165.
Jiang Nan,Chen Xing,Zhou Kun,et al.Massive gray scale change benefits far-field adverse effects during focused ultrasound ablation in the treatment of benign uterine diseases[J].Journal of Chongqing Medical University,2023,48(2):162-166. DOI: 10.13406/j.cnki.cyxb.003165.
目的
2
评估团块状灰度变化能否减轻子宫良性疾病聚焦超声消融术中的远场不良反应。
方法
2
开展单中心回顾性临床观察研究,纳入重庆医科大学附属第二医院行聚焦超声消融术的40例子宫良性疾病。比较团块状灰度变化出现前后,在相同能量水平(最小不可耐受能量)下,术中即刻骶尾部或臀部疼痛、放射痛、会阴部痛、肛门胀痛的发生率及不良反应程度。
结果
2
在相同能量水平(最小不可耐受能量)下,
团块状灰度变化出现后术中即刻骶尾部或臀部疼痛、放射痛、会阴部痛、肛门胀痛的发生率及不良反应程度明显低于团块状灰度变化出现前(
P
<
0.05)。
结论
2
团块状灰度变化能减轻子宫良性疾病聚焦超声消融术中的远场不良反应。
Objective
2
To explore whether the massive gray scale change(MGSC) can benefit far-field adverse effects during focused ultrasound ablation(FUA) in the treatment of benign uterine diseases.
Methods
2
In a single-center retrospective clinical observation study,40 patients with benign uterine diseases were treated with FUA in The Second Affiliated Hospital of Chongqing Medical University. Before and after the occurrence of MGSC,the incidence of far-field adverse effects such as sacrococcygeal or hip pain,radiation pain,perineal pain,anal distension pain and the levels of adverse effects were compared under the same energy level(the lowest intolerant energy).
Results
2
Under the same energy level(the lowest intolerant energy),the incidence of sacrococcygeal or hip pain,radiation pain,perineal pain,anal distension pain and the levels of adverse effects immediately after the occurrence of MGSC were significantly lower than those before the occurrence(
P
<
0.05).
Conclusion
2
The MGSC can reduce far-field adverse effects during FUA in the treatment of benign uterine diseases.
Chang CT , Jeng CJ , Long CY , et al . High-intensity focused ultrasound treatment for large and small solitary uterine fibroids [J ] . Int J Hyperth , 2022 , 39 ( 1 ): 485 - 489 .
Yan L , Huang HM , Lin JW , et al . High-intensity focused ultrasound treatment for symptomatic uterine fibroids:a systematic review and meta-analysis [J ] . Int J Hyperth , 2022 , 39 ( 1 ): 230 - 238 .
Li XL , Zhu XG , He SL , et al . High-intensity focused ultrasound in the management of adenomyosis:long-term results from a single center [J ] . Int J Hyperth , 2021 , 38 ( 1 ): 241 - 247 .
何玉春 , 罗 爽 , 黄国华 , 等 . 聚焦超声消融治疗子宫良性疾病不良反应分析 [J ] . 中国实用妇科与产科杂志 , 2020 , 36 ( 3 ): 272 - 275 .
He YC , Luo S , Huang GH , et al . Adverse effect analysis of focused ultrasound ablation in the treatment of benign uterine diseases [J ] . Chin J Pract Gynecol Obstet , 2020 , 36 ( 3 ): 272 - 275 .
Wang JQ , Zhang L , Zhang J , et al . Clinical usefulness of the microbubble contrast agent SonoVue in enhancing the effects of high-intensity focused ultrasound for the treatment of adenomyosis [J ] . J Ultrasound Med , 2018 , 37 ( 12 ): 2811 - 2819 .
Liu Y , Zhang WW , He M , et al . Adverse effect analysis of high-intensity focused ultrasound in the treatment of benign uterine diseases [J ] . Int J Hyperthermia , 2018 , 35 ( 1 ): 56 - 61 .
冉隆青 , 魏安宁 , 刘怀清 , 等 . 镇静镇痛方案用于高强度聚焦超声治疗子宫肌瘤的临床研究 [J ] . 中国医刊 , 2013 , 48 ( 12 ): 45 - 47 .
Ran LQ , Wei AN , Liu HQ , et al . The protocol for sedation and analgesia in treatment of uterine fibroids by HIFU:a clinical study [J ] . Chin J Med , 2013 , 48 ( 12 ): 45 - 47 .
万 丽 , 赵 晴 , 陈 军 , 等 . 疼痛评估量表应用的中国专家共识(2020版) [J ] . 中华疼痛学杂志 , 2020 , 16 ( 3 ): 177 - 187 .
Wan L , Zhao Q , Chen J , et al . Expert consensus on the application of pain evaluation questionnaires in China(2020) [J ] . Chin J Painol , 2020 , 16 ( 3 ): 177 - 187 .
祝宝让 , 李 静 , 盖绿华 , 等 . 经皮无水乙醇+碘油注射联合超声消融治疗子宫肌瘤 [J ] . 中国介入影像与治疗学 , 2015 , 12 ( 7 ): 395 - 398 .
Zhu BR , Li J , Gai LH , et al . Percutaneous ethanol + lipiodol injection combined with high intensity focused ultrasound in treatment of uterine fibroids [J ] . Chin J Interv Imaging Ther , 2015 , 12 ( 7 ): 395 - 398 .
胡 亮 , 陈文直 , 陈锦云 , 等 . 超声消融邻近骶尾部子宫肌瘤的临床策略及其安全性的随机对照研究 [J ] . 重庆医科大学学报 , 2012 , 37 ( 1 ): 75 - 78 .
Hu L , Chen WZ , Chen JY , et al . Clinical strategy on ultrasound ablation for uterine fibroids close to sacrococcyx and its safety:a randomized controlled trial [J ] . J Chongqing Med Univ , 2012 , 37 ( 1 ): 75 - 78 .
Li DD , Gong CM , Bai J , et al . Analysis of magnetic resonance signal intensity changes in the sacrococcygeal region of patients with uterine fibroids treated with high intensity focused ultrasound ablation [J ] . Int J Hyperthermia , 2020 , 37 ( 1 ): 404 - 413 .
Zhang YJ , Xiao ZB , Lv FR , et al . MRI evaluation of endopelvic fascial swelling and analysis of influencing factors in patients with uterine fibroids after high-intensity focused ultrasound ablation [J ] . Int J Hyperthermia , 2020 , 37 ( 1 ): 175 - 181 .
张雅姣 , 肖智博 , 吕富荣 , 等 . 子宫肌瘤HIFU术后骶骨MR异常信号的影响因素研究 [J ] . 介入放射学杂志 , 2019 , 28 ( 11 ): 1066 - 1070 .
Zhang YJ , Xiao ZB , Lü FR , et al . The influencing factors of sacrum abnormal MR signal occurring after HIFU for uterine fibroids [J ] . J Interv Radiol , 2019 , 28 ( 11 ): 1066 - 1070 .
郑安琪 , 陈锦云 , 肖智博 , 等 . 邻近骶尾部子宫肌瘤超声消融后周围组织损伤的MRI评价 [J ] . 中国医学影像学杂志 , 2021 , 29 ( 5 ): 493 - 497,502 .
Zheng AQ , Chen JY , Xiao ZB , et al . MRI evaluation of surrounding tissue damages after ultrasonic ablation of uterine fibroids adjacent to the sacrococcyx [J ] . Chin J Med Imaging , 2021 , 29 ( 5 ): 493 - 497,502 .
唐瑞遥 , 陈锦云 . 改变组织声环境增效高强度聚焦超声方法研究进展 [J ] . 现代医药卫生 , 2015 , 31 ( 11 ): 1635 - 1637 .
Tang RY , Chen JY . Research of improving tissue acoustic environment to enhance effect of high intensity focused ultrasound [J ] . J Mod Med Heal , 2015 , 31 ( 11 ): 1635 - 1637 .
Huang LH , Zhou K , Zhang J , et al . Efficacy and safety of high-intensity focused ultrasound ablation for hepatocellular carcinoma by changing the acoustic environment:microbubble contrast agent(SonoVue) and transcatheter arterial chemoembolization [J ] . Int J Hyperthermia , 2019 , 36 ( 1 ): 244 - 252 .
Cheng C , Xiao Z , Huang G , et al . Enhancing ablation effects of a microbubble contrast agent on high-intensity focused ultrasound:an experimental and clinical study [J ] . BJOG , 2017 , 124 ( Suppl 3 ): 78 - 86 .
张 睿 , 张义彬 , 马纪江 , 等 . 探讨缩宫素在高强度聚焦超声结合超声引导下瘤内无水乙醇注射治疗子宫肌瘤时的应用价值 [C ] // 中国超声医学工程学会第三届全国介入超声医学学术会议论文集 , 2015 : 153 - 154 .
Zhang R , Zhang YB , Ma JJ , et al . To explore the application value of oxytocin in the treatment of hysteromyoma by high intensity focused ultrasound combined with ultrasound-guided intratumoral absolute ethanol injection [C ] // Proceedings of the third National Academic Conference on interventional ultrasound medicine of Chinese society of ultrasonic medical engineering , 2015 : 153 - 154 .
Chen Y , Jiang J , Zeng YH , et al . Effects of a microbubble ultrasound contrast agent on high-intensity focused ultrasound for uterine fibroids:a randomised controlled trial [J ] . Int J Hyperth , 2018 , 34 ( 8 ): 1311 - 1315 .
0
Views
4
下载量
0
CSCD
Publicity Resources
Related Articles
Related Author
Related Institution
京公网安备11010802024621
