Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma

ZHU Zi-yu; LIU Xiao-dong; QIAN Bao

doi:10.11659/jjssx.12E024117

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Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma

Clinical Research | 更新时间：2025-10-24

- Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 34, Issue 10, Pages: 900-903(2025)
- 作者机构：
  
  佳木斯市中心医院神经外科，黑龙江佳木斯 154002
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.12E024117
  CLC： R739.41
- Received：20 December 2024，
  
  Published：25 October 2025
- 稿件说明：
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朱子煜,刘晓东,钱宝.显微镜下全切术对脑胶质瘤患者脑血流灌注及认知功能的影响[J].局解手术学杂志,2025,34(10):900-903.

ZHU Zi-yu,LIU Xiao-dong,QIAN Bao.Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(10):900-903.
朱子煜,刘晓东,钱宝.显微镜下全切术对脑胶质瘤患者脑血流灌注及认知功能的影响[J].局解手术学杂志,2025,34(10):900-903. DOI： 10.11659/jjssx.12E024117.

ZHU Zi-yu,LIU Xiao-dong,QIAN Bao.Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(10):900-903. DOI： 10.11659/jjssx.12E024117.

摘要

目的

探讨显微镜下全切术对脑胶质瘤患者脑血流灌注及认知功能的影响。

方法

回顾性分析我院收治的80例脑胶质瘤患者的临床资料。根据手术方法不同进行分组，其中采用传统开颅手术治疗的38例患者为传统组，采用显微镜下全切术治疗的42例患者为显微镜组。比较2组患者手术相关指标、脑血流灌注指标、认知功能及复发情况。

结果

显微镜组患者手术时间、术后下床活动时间及住院时间短于传统组，术中出血量低于传统组，切口长度小于传统组，差异均有统计学意义（

0.05）。术后6个月，显微镜组患者大脑皮层

N-NH

标准摄取值大于传统组（

0.05）。术后6个月，显微镜组患者定向力、即刻记忆力、注意力和计算力、延迟记忆力、语言功能评分及简易智能状态检查量表总分均高于传统组（

0.05）。术后1年，显微镜组患者复发率为4.76%，低于传统组的23.68%，差异有统计学意义（

0.05）。

结论

与传统开颅手术相比，采用显微镜下全切术治疗脑胶质瘤患者更具有优势，其能够优化手术指标，改善患者术后脑血流灌注，恢复认知功能，且术后复发率较低。

Abstract

Objective

To explore the effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma.

Methods

The clinical data of 80 glioma patients admitted to our hospital were retrospectively analyzed. The grouping were conducted according to different surgical methods，among which 38 patients treated with traditional craniotomy were included in the traditional group，and 42 patients treated with microscopic total resection were included in the microscopic group. The surgery-related indicators，cerebral blood perfusion indexes，cognitive function and recurrence of patients in the two groups were compared.

Results

The surgical time，time to get out of bed，and hospital stay of patients in the microscopic group were shorter than those in the traditional group，the intraoperative blood loss was lower than that in the traditional group，and the incision length was smaller than that in the traditional group，with statistically significant differences （

0.05）. Six months after surgery，the standard uptake value of

N-NH

in the cerebral cortex of patients

in the microscopic group was higher than that in the traditional group （

0.05）. Six months after surgery，the scores of directional ability，immediate memory，attention and calculation ability，delayed memory，and language function，and total mini-mental state examination score of patients in the microscopic group were higher than those in the traditional group （

0.05）. One year after surgery，the recurrence rate of patients in the microscopic group was 4.76%，which was lower than that in the traditional group of 23.68%，with statistically significant difference （

0.05）.

Conclusion

Compared with traditional craniotomy，microscopic total resection is more advantageous for patients with glioma，which can optimize surgical indicators，ameliorate postoperative cerebral blood flow perfusion，and restore cognitive function，with a lower postoperative recurrence rate.

关键词

Keywords

references

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