内江市中医医院骨外科,四川 内江 641000
Received:09 September 2025,
Published:25 April 2026
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罗强,张豪,李德志等.体外冲击波疗法联合单髁置换术治疗膝关节内侧间室骨性关节炎的效果[J].局解手术学杂志,2026,35(04):285-289.
LUO Qiang,ZHANG Hao,LI De-zhi,et al.Outcome of extracorporeal shock wave therapy combined with unicompartmental knee arthroplasty in treating medial compartment knee osteoarthritis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(04):285-289.
罗强,张豪,李德志等.体外冲击波疗法联合单髁置换术治疗膝关节内侧间室骨性关节炎的效果[J].局解手术学杂志,2026,35(04):285-289. DOI: 10.11659/jjssx.09E025037.
LUO Qiang,ZHANG Hao,LI De-zhi,et al.Outcome of extracorporeal shock wave therapy combined with unicompartmental knee arthroplasty in treating medial compartment knee osteoarthritis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(04):285-289. DOI: 10.11659/jjssx.09E025037.
目的
2
观察体外冲击波疗法(ESWT)联合单髁置换术(UKA)治疗膝关节内侧间室骨性关节炎患者的效果。
方法
2
收集2022年5月至2024年5月于本院就诊的68例膝关节内侧间室骨性关节炎患者资料,根据治疗方法不同分为对照组(接受UKA治疗)和观察组(接受UKA联合ESWT治疗),每组34例。比较2组患者美国膝关节协会评分(KSS)、膝关节活动度(ROM)、血清炎症及疼痛因子水平[白细胞介素(IL)-1β、IL-6、肿瘤坏死因子-α(TNF-α)以及前列腺素E2(PGE2)]、WHO生活质量测定量表简表(WHOQOL-BREF)评分。记录2组患者术后3个月内并发症发生情况。
结果
2
2组患者术后KSS评分逐渐升高,膝关节ROM逐渐增大,差异均有统计学意义(
P
<
0.05);术后1个月、3个月,观察组患者膝关节评分、功能评分高于对照组,膝关节ROM大于对照组,差异均有统计学意义(
P
<
0.05)。2组患者术后血清炎症及疼痛因子水平逐渐降低(
P
<
0.05);术后1个月、3个月,观察组患者IL-1β、IL-6、TNF-α、PGE2水平均显著低于对照组(
P
<
0.05)。2组患者术后3个月WHOQOL-BREF各维度评分均高于术前(
P
<
0.05),且观察组患者术后3个月WHOQOL-BREF各维度评分显著高于对照组(
P
<
0.05)。观察组患者术后3个月并发症发生率显著低于对照组(
P
<
0.05)。
结论
2
UKA联合ESWT能够显著促进膝关节内侧间室骨性关节炎患者的膝关节功能恢复,减轻疼痛,降低血清炎症因子水平,减少术后并发症发生,从而显著提升生活质量。
Objective
2
To assess the outcome of extracorporeal shock wave therapy (ESWT) combined with unicompartmental knee arthroplasty (UKA) in the treatment of patients with medial compartment knee osteoarthritis.
Methods
2
The clinical data of 68 patients with medial compartment knee osteoarthritis who were treated at our hospital from May 2022 to May 2024 were collected.The patients were divided into the control group (received UKA alone) and the observation group (received UKA combined with ESWT) according to the different treatments, with 34 cases in each group. The two groups were compared in terms of the American Knee Society Score (KSS), knee range of motion (ROM), serum levels of inflammatory and pain-related factors [interleukin (IL)-1β, IL-6, tumor necrosis factor-alpha (TNF-α), and prostaglandin E2 (PGE2)],and the World Health Organization Quality of Life-Brief Version (WHOQOL-BREF) scores.The occurrence of complications within 3 months after surgery was recorded in both groups.
Results
2
The postoperative KSS scores and knee ROM in both groups gradually increased over time, with statistically significant differences (
P
<
0.05). At 1 month and 3 months after surgery, the knee scores and function scores in the observation group were higher than those in the control group, and the knee ROM was greater than that in the control group, with statistically significant differences (
P
<
0.05). The levels of serum inflammatory and pain-related factors in both groups gradually decreased after surgery (
P
<
0.05). At 1 month and 3 months after surgery, the levels of IL-1β, IL-6, TNF-α, and PGE2 in the observation group were significantly lower than those in the control group (
P
<
0.05). At 3 months after surgery, all domain scores of the WHOQOL-BREF in both groups were significantly higher than those before surgery (
P
<
0.05), and all domain scores of the WHOQOL-BREF in the observation group were significantly higher than those in the control group (
P
<
0.05). The incidence of complications 3 months after surgery in the observation group was significantly lower than that in the control group (
P
<
0.05).
Conclusion
2
The combination of UKA and ESWT can significantly promote the recovery of knee function in patients with medial compartment knee osteoarthritis, alleviate pain,reduce levels of serum inflammatory factors,and decrease the incidence of postoperative complications,thereby significantly improving quality of life.
王丽敏 , 尚少梅 , 陈泓伯 . 症状性膝关节骨性关节炎发病风险评分表及使用手册的开发 [J]. 中国护理管理 , 2023 , 23 ( 12 ): 1905 - 1909 . doi: 10.3969/j.issn.1672-1756.2023.12.027 http://dx.doi.org/10.3969/j.issn.1672-1756.2023.12.027 .
黄臻 , 邓璐 , 陈文革 , 等 . 单髁置换术联合关节腔内注射富血小板血浆治疗膝关节内侧间室骨性关节炎疗效观察 [J]. 中国骨与关节损伤杂志 , 2024 , 39 ( 4 ): 393 - 396 .
闫祥甲 , 孙自力 , 蒋俊 , 等 . 单髁关节置换术与全膝关节置换术治疗膝关节内侧间室骨性关节炎术后运动功能恢复的对照研究 [J]. 生物骨科材料与临床研究 , 2024 , 21 ( 1 ): 26 - 30 . doi: 10.3969/j.issn.1672-5972.2024.01.005 http://dx.doi.org/10.3969/j.issn.1672-5972.2024.01.005 .
王欢欢 , 闵红巍 . 体外冲击波治疗骨性关节炎的研究现状及作用机制 [J]. 医学综述 , 2023 , 29 ( 1 ): 98 - 103 .
段好阳 , 张国栋 , 尹明 , 等 . 体外冲击波疗法治疗老年膝骨性关节炎的研究进展 [J]. 中国老年学杂志 , 2023 , 43 ( 13 ): 3320 - 3324 . doi: 10.3969/j.issn.1005-9202.2023.13.061 http://dx.doi.org/10.3969/j.issn.1005-9202.2023.13.061 .
韩良 , 姜效韦 , 郭宇 , 等 . 聚焦式冲击波治疗创伤性膝关节骨性关节炎的疗效观察 [J]. 中国骨与关节损伤杂志 , 2024 , 39 ( 2 ): 191 - 194 . doi: 10.7531/j.issn.1672-9935.2024.02.019 http://dx.doi.org/10.7531/j.issn.1672-9935.2024.02.019 .
中国骨关节炎诊疗指南专家组 , 中国老年保健协会疼痛病学分会 , 黄东 , 等 . 中国骨关节炎诊疗指南(2024版) [J]. 中华疼痛学杂志 , 2024 , 20 ( 3 ): 323 - 338 . doi: 10.3760/cma.j.cn101658-20240618-00074 http://dx.doi.org/10.3760/cma.j.cn101658-20240618-00074 .
Kim KI , Lee MC , Lee JH , et al . Clinical efficacy and safety of the intra-articular injection of autologous adipose-derived mesenchymal stem cells for knee osteoarthritis: a phase Ⅲ, randomized, double-blind, placebo-controlled trial [J]. Am J Sports Med , 2023 , 51 ( 9 ): 2243 - 2253 . doi: 10.1177/03635465231152341 http://dx.doi.org/10.1177/03635465231152341 .
Rigoni S , Libera MD , Pigatto D , et al . Comparison between patient specific instrumentation and traditional technique in patients with total knee arthroplasty: an observational perspective study [J]. J Orthop , 2021 , 23 : 264 - 272 . doi: 10.1016/j.jor.2021.01.013 http://dx.doi.org/10.1016/j.jor.2021.01.013 .
王志英 , 彭智烨 , 贾永会 . 小针刀松解术松解股直肌及股外侧肌起点对改善膝关节骨性关节炎中膝关节活动度的临床研究 [J]. 生命科学仪器 , 2023 , 21 ( z2 ): 21 . doi: 10.11967/202301217 http://dx.doi.org/10.11967/202301217 .
Bouras T , Tzanos IA , Forster M , et al . Correlation of quality of life with instrumented analysis of a total knee arthroplasty series at the long-term follow-up [J]. Eur J Orthop Surg Traumatol , 2021 , 31 ( 6 ): 1171 - 1177 . doi: 10.1007/s00590-020-02867-0 http://dx.doi.org/10.1007/s00590-020-02867-0 .
Endisha H , Datta P , Sharma A , et al . MicroRNA-34a-5p promotes joint destruction during osteoarthritis [J]. Arthritis Rheumatol , 2021 , 73 ( 3 ): 426 - 439 . doi: 10.1002/art.41552 http://dx.doi.org/10.1002/art.41552 .
张梅莹 , 徐迈 , 戴世友 , 等 . 固定平台单髁置换联合髁间窝成形术治疗中度屈曲畸形膝内侧间室骨关节炎的疗效分析 [J]. 实用骨科杂志 , 2024 , 30 ( 10 ): 890 - 894 . doi: 10.3760/cma.j.issn.1008-5572.2024.10.105 http://dx.doi.org/10.3760/cma.j.issn.1008-5572.2024.10.105 .
郁少林 , 李宏宇 , 匡萃琳 , 等 . 关节镜手术和体外冲击波治疗膝关节骨性关节炎的疗效比较 [J]. 中华物理医学与康复杂志 , 2022 , 44 ( 4 ): 334 - 337 . doi: 10.3760/cma.j.issn.0254-1424.2022.04.010 http://dx.doi.org/10.3760/cma.j.issn.0254-1424.2022.04.010 .
Uysal A , Yildizgoren MT , Guler H , et al . Effects of radial extracorporeal shock wave therapy on clinical variables and isokinetic performance in patients with knee osteoarthritis:a prospective,randomized,single-blind and controlled trial [J]. Int Orthop , 2020 , 44 ( 7 ): 1311 - 1319 . doi: 10.1007/s00264-020-04541-w http://dx.doi.org/10.1007/s00264-020-04541-w .
李守刚 , 黎华茂 . 臭氧、玻璃酸钠联合体外冲击波治疗膝关节骨性关节炎的疗效分析 [J]. 华南国防医学杂志 , 2023 , 37 ( 7 ): 570 - 575 . doi: 10.13730/j.issn.2097-2148.2023.07.006 http://dx.doi.org/10.13730/j.issn.2097-2148.2023.07.006 .
常毓文 , 季晶俊 . 放散式体外冲击波穴位治疗联合独活寄生汤对老年膝骨性关节炎疗效的影响 [J]. 湖北中医药大学学报 , 2021 , 23 ( 4 ): 100 - 103 . doi: 10.3969/j.issn.1008-987x.2021.04.29 http://dx.doi.org/10.3969/j.issn.1008-987x.2021.04.29 .
郝彦明 , 高焱 , 叶晓生 , 等 . 膝关节单髁置换术治疗膝关节单间室骨性关节炎 [J]. 中国骨与关节损伤杂志 , 2024 , 39 ( 2 ): 188 - 191 . doi: 10.7531/j.issn.1672-9935.2024.02.018 http://dx.doi.org/10.7531/j.issn.1672-9935.2024.02.018 .
李晓旭 , 夸新友 , 牛满拉吉 , 等 . 体外冲击波联合藏医能秀疗法治疗膝关节骨性关节炎的临床观察 [J]. 西部医学 , 2024 , 36 ( 8 ): 1161 - 1165 . doi: 10.3969/j.issn.1672-3511.2024.08.011 http://dx.doi.org/10.3969/j.issn.1672-3511.2024.08.011 .
史涛 , 黄佑庆 , 何晓峰 , 等 . 体外冲击波联合玻璃酸钠治疗膝骨性关节炎的临床疗效 [J]. 昆明医科大学学报 , 2022 , 43 ( 3 ): 80 - 85 . doi: 10.12259/j.issn.2095-610X.S20220311 http://dx.doi.org/10.12259/j.issn.2095-610X.S20220311 .
孙庆华 , 马文泽 , 王春亮 . 胫骨内侧高位截骨术与单髁置换术治疗膝关节内侧间室骨性关节炎的比较 [J]. 中国骨与关节损伤杂志 , 2021 , 36 ( 8 ): 840 - 842 . doi: 10.3969/j.issn.1000-7377.2021.09.019 http://dx.doi.org/10.3969/j.issn.1000-7377.2021.09.019 .
王瑞松 , 全健 , 李锐 , 等 . 关节镜下纳米微骨折骨髓刺激增强术联合冲击波治疗膝骨性关节炎软骨损伤临床疗效观察 [J]. 陕西医学杂志 , 2021 , 50 ( 9 ): 1119 - 1122 . doi: 10.3969/j.issn.1000-7377.2021.09.019 http://dx.doi.org/10.3969/j.issn.1000-7377.2021.09.019 .
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