Clinical value of narrow band imaging assisted thulium fiber laser en-bloc resection for non-muscle-invasive bladder cancer

LI Jia; LYU Dong-chen; LI Xin-hua; ZANG Tian-ming; DANG Yue; GUO Bo-yang; LI San-xiang

doi:10.11659/jjssx.06E025116

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Clinical value of narrow band imaging assisted thulium fiber laser en-bloc resection for non-muscle-invasive bladder cancer

Clinical Research | 更新时间：2026-06-16

- Clinical value of narrow band imaging assisted thulium fiber laser en-bloc resection for non-muscle-invasive bladder cancer
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 35, Issue 6, Pages: 534-538(2026)
- 作者机构：
  
  1.内蒙古自治区人民医院泌尿外科，内蒙古呼和浩特 010017
  2.包头医学院研究生院，内蒙古包头 014040
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.06E025116
  CLC： R699.5
- Received：24 June 2025，
  
  Published：25 June 2026
- 稿件说明：
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李佳,吕东晨,李鑫华等.窄谱光成像辅助铥激光整块剜除术治疗非肌层浸润性膀胱癌的临床价值[J].局解手术学杂志,2026,35(06):534-538.

LI Jia,LYU Dong-chen,LI Xin-hua,et al.Clinical value of narrow band imaging assisted thulium fiber laser en-bloc resection for non-muscle-invasive bladder cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(06):534-538.
李佳,吕东晨,李鑫华等.窄谱光成像辅助铥激光整块剜除术治疗非肌层浸润性膀胱癌的临床价值[J].局解手术学杂志,2026,35(06):534-538. DOI： 10.11659/jjssx.06E025116.

LI Jia,LYU Dong-chen,LI Xin-hua,et al.Clinical value of narrow band imaging assisted thulium fiber laser en-bloc resection for non-muscle-invasive bladder cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(06):534-538. DOI： 10.11659/jjssx.06E025116.

摘要

目的

探讨经尿道窄谱光成像（NBI）辅助铥激光（TFL）膀胱肿瘤整块剜除术（ERBT）在非肌层浸润性膀胱癌治疗中的安全性与临床疗效。

方法

选取内蒙古自治区人民医院2021年1月至2023年12月收治的260例非肌层浸润性膀胱癌患者为研究对象进行回顾性分析，采用经尿道窄谱光成像辅助铥激光膀胱肿瘤整块剜除术治疗的76例患者纳入NBI-TFL-ERBT组，采用普通白光成像（WLI）下经尿道膀胱肿瘤电切术（TURBT）治疗的184例患者纳入WLI-TURBT组。统计并比较2组患者的手术时间、术后尿管留置时间、术后住院时间、手术并发症发生率、病理标本肌层检出率、复发率及无病生存率。

结果

2组患者在手术时间、术后住院时间以及膀胱出血发生率方面比较，差异无统计学意义（

0.05）。与WLI-TURBT组比较，NBI-TFL-ERBT组患者术后尿管留置时间较短（

0.05），闭孔神经反射及膀胱穿孔的发生率、并发症总发生率均较低（

0.05），且术后病理标本肌层检出率更高（

0.05）。随访结果显示，与WLI-TURBT组比较，NBI-TFL-ERBT组患者在术后6个月、1年、2年以及随访截止时的肿瘤复发率更低（

0.05），无病生存率更高（

0.05）。

结论

经尿道窄谱光成像辅助铥激光整块剜除术治疗非肌层浸润性膀胱癌安全可行。相较于传统电切术，该术式能显著降低并发症风险，促进术后恢复，改善患者生存获益。

Abstract

Objective

To explore the safety and clinical efficacy of transurethral narrow band imaging （NBI） assisted thulium fiber laser （TFL） en-bloc resection of bladder tumor （ERBT） in the treatment of non-muscle-invasive bladder cancer.

Methods

A retrospective analysis was performed on 260 patients with non-muscle-invasive bladder cancer admitted to People's Hospital of Inner Mongolia Autonomous Region from January 2021 to December 2023. Seventy-six patients treated with transurethral narrow band imaging assisted thulium fiber laser en-bloc resection of bladder tumor were enrolled in the NBI-TFL-ERBT group， and 184 patients treated with conventional transurethral resection of bladder tumor （TURBT） under white light imaging （WLI） were enrolled in the WLI-TURBT group. The operation time， postoperative catheterization time，postoperative hospital stay，incidence of surgical complications，detection rate of muscular layer in pathological specimens， recurrence rate and disease-free survival rate were statistically compared between the two groups.

Results

There were no significant differences between the two groups in terms of operative time，postoperative hospital stay，and the incidence of bladder hemorrhage （

0.05）.Compared with the WLI-TURBT group，patients of the NBI-TFL-ERBT group had shorter postoperative cathe

terization time （

0.05）， lower incidences of obturator nerve reflex， bladder perforation and overall complications （

0.05）， and higher detection rate of muscular layer in pathological specimens （

0.05）.Follow-up results showed that compared with the WLI-TURBT group， patients of the NBI-TFL-ERBT group had lower tumor recurrence rates at 6 months， 1 year， 2 years after surgery and at the end of follow-up （

0.05）， with a higher disease-free survival rate （

0.05）.

Conclusion

Transurethral narrow band imaging assisted thulium fiber laser en-bloc resection of bladder tumor is safe and feasible in the treatment of non-muscle-invasive bladder cancer. Compared with the conventional transurethral resection of bladder tumor， this technique can significantly reduce the risk of complications， promote postoperative recovery and improve survival benefits of patients.

关键词

Keywords

references

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