Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity

CAO Yong; BO Qin-xia; CAO Li; JIANG Rong; YI Long

doi:10.11659/jjssx.06E024082

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Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity

Clinical Research | 更新时间：2025-03-25

- Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 34, Issue 3, Pages: 254-257(2025)
- 作者机构：
  
  1.陆军军医大学第一附属医院肝胆外科，重庆 400038
  2.陆军军医大学第一附属医院体检中心，重庆 400038
  3.陆军军医大学军事预防医学系军队营养与食品卫生学教研室，重庆 400038
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.06E024082
  CLC： R575.5;R589.2;G804.5;G806
- Received：20 June 2024，
  
  Published：25 March 2025
- 稿件说明：
移动端阅览
曹永,伯秦霞,曹利等.不同运动方式对非酒精性脂肪肝合并肥胖人群的影响[J].局解手术学杂志,2025,34(03):254-257.

CAO Yong,BO Qin-xia,CAO Li,et al.Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(03):254-257.
曹永,伯秦霞,曹利等.不同运动方式对非酒精性脂肪肝合并肥胖人群的影响[J].局解手术学杂志,2025,34(03):254-257. DOI： 10.11659/jjssx.06E024082.

CAO Yong,BO Qin-xia,CAO Li,et al.Effect of different exercise modes on people with nonalcoholic fatty liver disease and obesity[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2025,34(03):254-257. DOI： 10.11659/jjssx.06E024082.

摘要

目的

探讨不同运动方式对非酒精性脂肪肝（NAFLD）合并肥胖人群的影响，为该类人群的康复治疗提供运动处方参考。

方法

选取2023年1-9月在陆军军医大学第一附属医院体检中心通过健康筛查确诊为NAFLD合并肥胖的患者，采用随机数字表法分成3组，每组52例。有氧组患者进行有氧运动干预，抗阻组患者进行抗阻运动干预，联合组患者进行有氧+抗阻联合运动干预，持续12周。在干预前后，分别检测并比较各组患者的肝功能指标[包括丙氨酸转氨酶（ALT）、γ-谷氨酰转移酶（GGT）、天冬氨酸转氨酶（AST）、白蛋白、胆红素）]、BMI、腰围、血糖及三酰甘油（TG）水平，分析不同运动方式对NAFLD合并肥胖患者各指标的改善效果。

结果

干预后，各组患者的BMI和腰围均显著下降（

0.05）；联合组的ALT、GGT、白蛋白、胆红素、TG和血糖较干预前显著改善（

0.05）。抗阻运动对ALT、GGT、AST和TG的改善效果优于有氧运动（

0.05），但对白蛋白、胆红素、BMI、腰围和血糖的改善效果与有氧运动相比无统计学差异（

0.05）；有氧+抗阻联合运动对BMI、腰围、白蛋白、胆红素和TG的改善效果优于单纯的抗阻运动和有氧运动（

0.05），但对ALT、GGT和AST的改善效果与单纯抗阻运动无统计学差异（

0.05）。

结论

针对NAFLD合并肥胖人群，建议采用有氧运动+抗阻联合运动的干预策略，可改善患者的肝功能、体脂分布及相关代谢指标，获得更优的治疗效果。

Abstract

Objective

To investigate the effect of different exercise modes on people with nonalcoholic fatty liver disease （NAFLD） and obesity，thereby providing evidence-based exercise prescriptions for the rehabilitation of this population.

Methods

Patients diagnosed with NAFLD and obesity through health screenings at the Physical Examination Center of First Affiliated Hospital of Army Medical University from January to September 2023 were selected and assigned into three groups by random number table method，with 52 cases in each group. The aerobic group underwent aerobic exercise，the resistance group underwent resistance exercise，and the combined group underwent a combination of aerobic and resistance exercise for a duration of 12 weeks. The liver function indicators ［including alanine aminotransferase（ALT），gamma-glutamyl transferase （GGT），aspartate aminotransferase （AST），albumin，and bilirubin］，BMI，waist circumference，blood glucose，and triglyceride （TG） levels in each group were detected and compared. The improvement effect of different exercise modes on the above various indexes in patients with NAFLD and obesity was analyzed.

Results

After intervention， BMI and waist circumference were significantly decreased in each group （

0.05）； and the ALT， GGT， albumin， bilirubin， TG and blood glucose of the combined group were significantly improved compared with those before intervention （

0.05）. Resistance exercise had a better improvement effect on the

ALT， GGT， AST and TG than aerobic exercise （

0.05）， while which had no significant difference in the albumin， bilirubin， BMI， waist circumference or blood glucose compared with aerobic exercise （

0.05）. The improvement effects of aerobic+resistance combined exercise on the BMI， waist circumference， albumin， bilirubin and TG were better than those of aerobic exercise and resistance exercise alone （

0.05）， while which had no significant difference in the improvement of the ALT， GGT or AST compared with resistance exercise alone （

0.05）.

Conclusion

For people with NAFLD and obesity，a combined aerobic and resistance exercise intervention is recommended，which can improve the liver function，body fat distribution and related metabolic indexes of patients，with better treatment results.

关键词

Keywords

references

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