Development and validation of a nomogram for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy

LIU Qian; YANG Jian; SHEN Xiao-fei; WANG Jiang-she

doi:10.11659/jjssx.04E025023

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Development and validation of a nomogram for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy

Clinical Research | 更新时间：2026-01-19

- Development and validation of a nomogram for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 35, Issue 1, Pages: 52-56(2026)
- 作者机构：
  
  1.南京医科大学附属儿童医院麻醉手术科，江苏南京 210018
  2.南京医科大学附属儿童医院耳鼻咽喉科，江苏南京 210018
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.04E025023
  CLC： R726.1
- Received：05 April 2025，
  
  Published：25 January 2026
- 稿件说明：
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刘倩,杨建,沈小飞等.扁桃体腺样体切除术儿童麻醉恢复期发生躁动的列线图建立及验证[J].局解手术学杂志,2026,35(01):52-56.

LIU Qian,YANG Jian,SHEN Xiao-fei,et al.Development and validation of a nomogram for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(01):52-56.
刘倩,杨建,沈小飞等.扁桃体腺样体切除术儿童麻醉恢复期发生躁动的列线图建立及验证[J].局解手术学杂志,2026,35(01):52-56. DOI： 10.11659/jjssx.04E025023.

LIU Qian,YANG Jian,SHEN Xiao-fei,et al.Development and validation of a nomogram for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(01):52-56. DOI： 10.11659/jjssx.04E025023.

摘要

目的

探讨扁桃体腺样体切除术儿童麻醉恢复期发生躁动的影响因素，并构建列线图模型。

方法

选取2021年1月至2023年12月我院收治的360例行扁桃体腺样体切除术的患儿，按照6∶4的比例随机分为建模组（216例）和验证组（144例）。通过单因素和多因素回归分析探讨扁桃体腺样体切除术儿童麻醉恢复期发生躁动的影响因素，并构建列线图模型，采用受试者工作特征（

ROC

）曲线评估模型的预测能力，采用校准曲线评估模型的一致性。

结果

年龄≤6岁、发育迟缓、术前焦虑、未使用右美托咪定和术后疼痛是扁桃体腺样体切除术儿童麻醉恢复期发生躁动的独立危险因素（

0.05）。建模组、验证组的曲线下面积（

AUC

）分别为0.84（95%

：0.79~0.90）、0.79（95%

：0.71~0.86）。2组校准曲线预测值与实际值接近，说明构建的模型一致性较好。

结论

年龄小、发育迟缓、术前焦虑、术后疼痛及未使用右美托咪定等是扁桃体腺样体切除术儿童麻醉恢复期发生躁动的影响因素，据此构建的列线图模型具有良好的预测价值。临床可根据此列线图制订早期干预方案，以减少儿童麻醉恢复期躁动的发生。

Abstract

Objective

To explore the influencing factors of emergence agitation during anesthesia recovery in pediatric adenotonsillectomy and to construct a nomogram model.

Methods

A total of 360 children who underwent pediatric adenotonsillectomy in our hospital from January 2021 to December 2023 were selected and randomly assigned to

the modeling group （216 cases）and the validation group （144 cases）in a ratio of 6∶4. The factors influencing emergence agitation during anesthesia recovery in pediatric adenotonsillectomy were investigated through univariate analysis and multivariate regression analysis， and a nomogram model was constructed. The predictive ability of the model was assessed by

receiver operating characteristic

（

ROC

） curve， and the consistency of the model was evaluated by calibration curve.

Results

Age≤6 years， developmental delay， preoperative anxiety，non-use of dexmedetomidine， and postoperative pain were independent risk factors for emergence agitation during anesthesia recovery in pediatric adenotonsillectomy（

0.05）. The

area under the curve

（

AUC

） was 0.84（95%

：0.79 to 0.90） for the modeling group and 0.79（95%

：0.71 to 0.86） for the validation group. The predicted value of the calibration curves for both groups was close to the actual value， indicating good consistency of the constructed model.

Conclusion

The influencing factors of emergence agitation during anesthesia recovery in pediatric adenotonsillectomy include younger age， developmental delay， preoperative anxiety， postoperative pain， and non-use of dexmedetomidine， and the nomogram model constructed accordingly demonstrates good predictive performance. It may assist in guiding early clinical interventions to reduce emergence agitation during pediatric anesthesia recovery.

关键词

Keywords

references

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