Comparison of the outcomes of two types of interbody fusion surgeries for grade Ⅰ lumbar spondylolisthesis

XIAO Liang; ZHAO Quan-lai; LI Yi-feng; ZHANG Yu

doi:10.11659/jjssx.03E026053

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Comparison of the outcomes of two types of interbody fusion surgeries for grade Ⅰ lumbar spondylolisthesis

Clinical Research | 更新时间：2026-07-31

- Comparison of the outcomes of two types of interbody fusion surgeries for grade Ⅰ lumbar spondylolisthesis
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 35, Issue 8, Pages: 703-707(2026)
- 作者机构：
  
  皖南医学院弋矶山医院脊柱骨科，安徽芜湖 241001
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.03E026053
  CLC： R683.2
- Received：09 March 2026，
  
  Revised：2026-05-11，
  
  Accepted：12 May 2026，
  
  Online First：31 July 2026，
  
  Published：25 August 2026
- 稿件说明：
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肖良,赵泉来,李逸峰等.两种椎体间融合术对Ⅰ度腰椎滑脱症的疗效比较[J].局解手术学杂志,2026,35(08):703-707.

XIAO Liang,ZHAO Quan-lai,LI Yi-feng,et al.Comparison of the outcomes of two types of interbody fusion surgeries for grade Ⅰ lumbar spondylolisthesis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(08):703-707.
肖良,赵泉来,李逸峰等.两种椎体间融合术对Ⅰ度腰椎滑脱症的疗效比较[J].局解手术学杂志,2026,35(08):703-707. DOI： 10.11659/jjssx.03E026053.

XIAO Liang,ZHAO Quan-lai,LI Yi-feng,et al.Comparison of the outcomes of two types of interbody fusion surgeries for grade Ⅰ lumbar spondylolisthesis[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(08):703-707. DOI： 10.11659/jjssx.03E026053.

摘要

目的

对比脊柱内镜下经椎间孔腰椎椎体间融合术（Endo-TLIF）与微创经椎间孔入路腰椎椎体间融合术（MIS-TLIF）治疗Ⅰ度腰椎滑脱症的临床疗效。

方法

选取2023年4月至2024年5月在我院接受手术治疗的30例单节段Ⅰ度腰椎滑脱症患者，根据手术方式不同，将其分为MIS-TLIF组（13例）和Endo-TLIF组（17例）。比较2组患者手术相关指标；分别采用视觉模拟量表（VAS）、Oswestry功能障碍指数（ODI）评估2组患者手术前后的疼痛情况及功能情况；比较2组患者滑脱复位率、术后椎间隙高度、节段融合率及并发症发生情况。

结果

Endo-TLIF组患者手术时间、术中透视次数均长/多于MIS-TLIF组（

0.05），术中出血量、术后总引流量和术后住院时间均明显少/短于MIS-TLIF组（

0.05）。Endo-TLIF组患者术后3 d、术后3个月、术后6个月的VAS评分均低于MIS-TLIF组；Endo-TLIF组患者术后3 d、术后3个月ODI评分高于MIS-TLIF组（

0.05），术后6个月ODI评分低于MIS-TLIF组（

0.05）。2组患者滑脱复位率、术后椎间隙高度及节段融合率比较，差异均无统计学意义（

0.05）。2组患者术后并发症总发生率比较，差异无统计学意义（

0.05）。

结论

Endo-TLIF与MIS-TLIF治疗Ⅰ度腰椎滑脱症均可获得较好的临床效果，但Endo-TLIF对近期预后的积极作用更明显。

Abstract

Objective

To compare the clinical outcomes of endoscopic transforaminal lumbar interbody fusion （Endo-TLIF） versus minimally invasive transforaminal lumbar interbody fusion （MIS-TLIF） for grade Ⅰ lumbar spondylolisthesis.

Methods

A total of 30 patients with single-segment grade Ⅰ lumbar spondylolisthesis who underwent surgical treatment in our hospital from April 2023 to May 2024 were enrolled.According to the different surgical methods，they were divided into the MIS‑TLIF group （

=13） and the Endo‑TLIF group （

=17）. The surgical-related indicators of both groups were compared. The pain levels and functional status of patients in the two groups before and after surgery

were assessed by visual analogue scale （VAS） and Oswestry disability index （ODI）.The slippage reduction rates，postoperative intervertebral space heights， segmental fusion rates， and incidences of complications were compared between the two groups.

Results

Endo‑TLIF group had significantly longer operative time and more intraoperative fluoroscopy times than those in the MIS‑TLIF group（

0.05）， while the intraoperative blood loss， total postoperative drainage volume and postoperative hospital stay were significantly less/shorter compared with the MIS-TLIF group （

0.05）. Endo‑TLIF group had significantly lower VAS scores at 3 days， 3 months， and 6 months postoperatively than those in the MIS‑TLIF group （

0.05）. The ODI scores in the Endo‑TLIF group were higher at 3 days and 3 months postoperatively， but lower at 6 months postoperatively compared with the MIS‑TLIF group （

0.05）. No statistically significant differences were observed in the slippage reduction rates， postoperative intervertebral space heights， or segmental fusion rates between the two groups （

0.05）. Similarly， no statistically significant differences were found in the overall incidences of complications after surgery between the two groups （

0.05）.

Conclusion

Both Endo-TLIF and MIS-TLIF can achieve good clinical outcomes in the treatment of gradeⅠ lumbar spondylolisthesis，while Endo-TLIF shows more pronounced positive effects on short-term prognosis.

关键词

Keywords

references

Xie H ， Ouyang Z ， Zhang H . Radiographic analysis of pedicle screw retractor-assisted transforaminal lumbar interbody fusion for single-segment spondylolisthesis in adults： a retrospective study and technical note ［J］. Orthop Surg ， 2022 ， 14 （ 9 ）： 2219 - 2229 . doi： 10.1111/os.13441 http://dx.doi.org/10.1111/os.13441 .

He D ， Li ZC ， Zhang TY ， et al . Prevalence of lumbar spondylolisthesis in middle-aged people in Beijing Community ［J］. Orthop Surg ， 2021 ， 13 （ 1 ）： 202 - 206 . doi： 10.1111/os.12871 http://dx.doi.org/10.1111/os.12871 .

Roh YH ， Lee JC ， Hwang J ， et al . Long-term clinical and radiological outcomes of minimally invasive transforaminal lumbar interbody fusion：10-year follow-up results ［J］. J Korean Med Sci ， 2022 ， 37 （ 13 ）： e105 . doi： 10.3346/jkms.2022.37.e105 http://dx.doi.org/10.3346/jkms.2022.37.e105 .

Yuan JJ ， Li G ， Liu Y ， et al . The association between sagittal spinopelvic alignment and persistent low back pain after posterior lumbar interbody fusion for treatment of mild l5-s1 spondylolisthesis：a retrospective study ［J］. Int J Gen Med ， 2022 ， 15 （ 3 ）： 4807 - 4816 . doi： 10.2147/IJGM.S353797 http://dx.doi.org/10.2147/IJGM.S353797 .

Chen M ， Cui J ， Liu Y ， et al . Comparison of safety and efficacy of posterior lumbar interbody fusion（PLIF） and modified transforaminal lumbar interbody fusion（M-TLIF） in the treatment of single-segment lumbar degenerative diseases ［J］. J Orthop Surg Res ， 2024 ， 19 （ 1 ）： 95 . doi： 10.1186/s13018-024-04531-3 http://dx.doi.org/10.1186/s13018-024-04531-3 .

Hao S ， Li H ， Liu S ， et al . The effect of intravenous unit-dose tranexamic acid on visible and hidden blood loss in posterior lumbar interbody fusion：a randomized clinical trial ［J］. Sci Rep ， 2023 ， 13 （ 1 ）： 4714 . doi： 10.1038/s41598-022-27307-3 http://dx.doi.org/10.1038/s41598-022-27307-3 .

Jin YM ， Chen Q ， Chen CY ， et al . Clinical research and technique note of TLIF by Wiltse approach for the treatment of degenerative lumbar ［J］. Orthop Surg ， 2021 ， 13 （ 5 ）： 1628 - 1638 . doi： 10.1111/os.13055 http://dx.doi.org/10.1111/os.13055 .

Kang MS ， Park JY ， Kim KH ， et al . Minimally invasive transforaminal lumbar interbody fusion with unilateral pedicle screw fixation：comparison between primary and revision surgery ［J］. Biomed Res Int ， 2014 ， 12 （ 56 ）： 92 - 99 . doi： 10.1155/2014/919248 http://dx.doi.org/10.1155/2014/919248 .

Hong JY ， Kim WS ， Park J ， et al . Comparison of minimally invasive and open TLIF outcomes with more than seven years of follow-up ［J］. N Am Spine Soc J ， 2022 ， 11 （ 56 ） 100 - 106 . doi： 10.1016/j.xnsj. 2022. 100131 http://dx.doi.org/10.1016/j.xnsj.2022.100131

Liu JB ， Wu JL ， Zuo R ， et al . Does MIS-TLIF or TLIF result in better pedicle screw placement accuracy and clinical outcomes with navigation guidance？［J］. BMC Musculoskelet Disord ， 2022 ， 23 （ 1 ）： 153 . doi： 10.1186/s12891-022-05106-1 http://dx.doi.org/10.1186/s12891-022-05106-1 .

Zhang H ， Zhou C ， Wang C ， et al . Percutaneous endoscopic transforaminal lumbar interbody fusion：technique note and comparison of early outcomes with minimally invasive transforaminal lumbar interbody fusion for lumbar spondylolisthesis ［J］. Int J Gen Med ， 2021 ， 14 （ 56 ）： 549 - 558 . doi： 10.2147/IJGM.S298591 http://dx.doi.org/10.2147/IJGM.S298591 .

Han L ， Li T ， Chen L ， et al . Effect of collagenase chemonucleolysis on residual pain after transforaminal lumbar endoscopic discectomy ［J］. J Pain Res ， 2023 ， 16 （ 35 ）： 1257 - 1265 . doi： 10.2147/JPR.S402534 http://dx.doi.org/10.2147/JPR.S402534 .

Epstein NE . More nerve root injuries occur with minimally invasive lumbar surgery：let's tell someone ［J］. Surg Neurol Int ， 2016 ， 7 （ 31 ）： S96 - S101 . doi： 10.4103/2152-7806.174896 http://dx.doi.org/10.4103/2152-7806.174896 .

Ruetten S ， Komp M ， Godolias G . An extreme lateral access for the surgery of lumbar disc herniations inside the spinal canal using the full-endoscopic uniportal transforaminal approach-technique and prospective results of 463 patients ［J］. Spine（Phila Pa 1976）， 2005 ， 30 （ 22 ）： 2570 - 2578 . doi： 10.1097/01.brs.0000186327.21435.cc http://dx.doi.org/10.1097/01.brs.0000186327.21435.cc .

Guo H ， Song Y ， Weng R ， et al . Comparison of clinical outcomes and complications between endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases：a systematic review and meta-analysis ［J］. Global Spine J ， 2023 ， 13 （ 5 ）： 1394 - 1404 . doi： 10.1177/21925682221142545 http://dx.doi.org/10.1177/21925682221142545 .

Haibier A ， Yusufu A ， Hang L ， et al . Comparison of clinical outcomes and complications between endoscopic and minimally invasive transforaminal lumbar interbody fusion for lumbar degenerative diseases：a systematic review and meta-analysis ［J］. J Orthop Surg Res ， 2024 ， 19 （ 1 ）： 92 . doi： 10.1186/s13018-024-04549-7 http://dx.doi.org/10.1186/s13018-024-04549-7 .

Kim HS ， Choi SH ， Shim DM ， et al . Advantages of new endoscopic unilateral laminectomy for bilateral decompression（ULBD） over conventional microscopic ULBD ［J］. Clin Orthop Surg ， 2020 ， 12 （ 3 ）： 330 - 336 . doi： 10.4055/cios19136 http://dx.doi.org/10.4055/cios19136 .

Lv Y ， Chen M ， Wang SL ， et al . Endo-TLIF versus MIS-TLIF in 1-segment lumbar spondylolisthesis：a prospective randomized pilot study ［J］. Clin Neurol Neurosurg ， 2022 ， 212 （ 45 ）： 106 - 109 . doi： 10.1016/j.clineuro.2021.107082 http://dx.doi.org/10.1016/j.clineuro.2021.107082 .

高永春，陈斌，李积然，等 . 经关节突入路单侧双通道内镜下腰椎椎间融合术治疗退行性腰椎滑脱症合并腰椎管狭窄症［J］. 系统医学， 2025 ， 10 （ 5 ）： 150 - 153 . doi： 10.19368/j.cnki.2096-1782. 2025.05.150 http://dx.doi.org/10.19368/j.cnki.2096-1782.2025.05.150 .

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