Evaluation and analysis of X-ray, ultrasonography, and MRI in assessing lesion extent of invasive breast cancer with extensive intraductal component

ZHAO Dong-xue; SHEN Dong-hua; JI Bo; ZHANG Yi; WANG Gong; HE Yao-hua

doi:10.11659/jjssx.02E026025

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Evaluation and analysis of X-ray, ultrasonography, and MRI in assessing lesion extent of invasive breast cancer with extensive intraductal component

Precise Diagnosis and Treatment of Breast and Thyroid Diseases | 更新时间：2026-10-26

- Evaluation and analysis of X-ray, ultrasonography, and MRI in assessing lesion extent of invasive breast cancer with extensive intraductal component
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 35, Issue 10, Pages: 845-848(2026)
- 作者机构：
  
  1.火箭军特色医学中心超声诊断科，北京 100032
  2.上海交通大学医学院附属仁济医院基础医学中心，上海 200001
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.02E026025
  CLC： R737.9;R445
- Received：04 February 2026，
  
  Revised：2026-09-17，
  
  Accepted：28 April 2026，
  
  Published：25 October 2026
- 稿件说明：
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赵冬雪,沈冬花,冀波等.X射线、超声与MRI对伴广泛导管内成分的浸润性乳腺癌病灶范围的评估分析[J].局解手术学杂志,2026,35(10):845-848.

ZHAO Dong-xue,SHEN Dong-hua,JI Bo,et al.Evaluation and analysis of X-ray, ultrasonography, and MRI in assessing lesion extent of invasive breast cancer with extensive intraductal component[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(10):845-848.
赵冬雪,沈冬花,冀波等.X射线、超声与MRI对伴广泛导管内成分的浸润性乳腺癌病灶范围的评估分析[J].局解手术学杂志,2026,35(10):845-848. DOI： 10.11659/jjssx.02E026025.

ZHAO Dong-xue,SHEN Dong-hua,JI Bo,et al.Evaluation and analysis of X-ray, ultrasonography, and MRI in assessing lesion extent of invasive breast cancer with extensive intraductal component[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(10):845-848. DOI： 10.11659/jjssx.02E026025.

摘要

目的

对比乳腺X射线、超声与MRI评估伴广泛导管内成分（EIC）的浸润性乳腺癌病灶范围的准确性，为术前精准评估提供影像学依据。

方法

回顾性纳入2020年1月至2026年3月于火箭军特色医学中心接受手术治疗的185例EIC阳性浸润性乳腺癌患者，所有患者术前均完成乳腺X射线、超声及MRI检查，以术后病理测量的病灶最大径为金标准，评估三种影像学检查的测量准确性与一致性，并按钙化状态、MRI病灶分型进行分层分析。

结果

MRI测量值与病理结果的相关性良好（Spearman相关系数

=0.738，

0.001），X射线（

=0.657，

0.001）、超声（

=0.511，

0.001）呈中等相关。无钙化病灶亚组中，MRI与病理结果的一致性最优（ICC=0.793，

0.001），达到优

秀等级；伴钙化病灶亚组中，X射线与病理结果的一致性最佳（ICC=0.700，

0.001），达到良好等级。MRI对三种病灶分型的测量结果与病理结果均保持良好一致性，其中对肿块伴非肿块强化型病灶的测量结果与病理结果的一致性最高（ICC=0.685，

0.001）。MRI测量绝对误差

5 mm的患者占比最高（57.3%），超声测量误差

10 mm的患者占比最高（29.7%）。

结论

三种影像学检查均可用于伴EIC浸润性乳腺癌的术前病灶范围评估，MRI整体准确性最优，X射线检查对伴钙化病灶的评估更具优势，超声可作为初筛手段联合其他检查完成全面评估。

Abstract

Objective

To compare the accuracy of X‑ray，ultrasonography and MRI in evaluating the lesion extent of invasive breast cancer with extensive intraductal component （EIC）， and to provide imaging evidence for precise preoperative assessment.

Methods

A total of 185 patients with EIC-positive invasive breast cancer who underwent surgery at PLA Rocket Force Characteristic Medical Center from January 2020 to March 2026 were retrospectively enrolled.All patients completed preoperative X‑ray，ultrasonography and MRI examinations. The maximum diameter of the lesion measured by postoperative pathology was used as the gold standard to evaluate the measurement accuracy and consistency of the three imaging modalities， and stratified analysis was performed according to calcification status and MRI lesion classification.

Results

MRI measurements showed good correlation with the pathological diagnosis （Spearman correlation coefficient

=0.738，

0.001）， while X‑ray（

=0.657，

0.001） and ultrasonography（

=0.511，

0.001） showed moderate correlation. In the non-calcified lesion subgroup， MRI achieved the optimal consistency with pathological diagnosis （ICC=0.793，

0.001）， reaching an excellent level； in the calcified lesion subgroup，X‑ray yielded the best consistency （ICC=0.700，

0.001）， reaching a good level. MRI maintained good consistency with pathological diagnosis across al

l three lesion subtypes， with the highest consistency for mass with non-mass enhancement lesions （ICC=0.685，

0.001）. The proportion of patients with absolute measurement error

5 mm was the highest in MRI （57.3%）， while the proportion of patients with measurement error

10 mm was the highest in ultrasonography（29.7%）.

Conclusion

All three imaging modalities can be applied to preoperative lesion extent assessment of invasive breast cancer with EIC. MRI has the best overall accuracy，X‑ray has greater advantages in evaluating calcified lesions， and ultrasonography can serve as an initial screening modality and be combined with other examinations to achieve comprehensive assessment.

关键词

Keywords

references

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