Relief effects of three minimally invasive treatment methods on patients with postherpetic neuralgia

ZHANG Lin; ZHOU Xing-yu; LIU Yong; LI Li

doi:10.11659/jjssx.02E025130

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Relief effects of three minimally invasive treatment methods on patients with postherpetic neuralgia

Clinical Research | 更新时间：2026-01-19

- Relief effects of three minimally invasive treatment methods on patients with postherpetic neuralgia
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 35, Issue 1, Pages: 42-46(2026)
- 作者机构：
  
  陆军军医大学第二附属医院疼痛与康复医学科，重庆 400037
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.02E025130
  CLC： R752.1+2
- Received：25 February 2025，
  
  Published：25 January 2026
- 稿件说明：
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张林,周星余,刘勇等.三种微创治疗方式对带状疱疹后神经痛患者的改善效果[J].局解手术学杂志,2026,35(01):42-46.

ZHANG Lin,ZHOU Xing-yu,LIU Yong,et al.Relief effects of three minimally invasive treatment methods on patients with postherpetic neuralgia[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(01):42-46.
张林,周星余,刘勇等.三种微创治疗方式对带状疱疹后神经痛患者的改善效果[J].局解手术学杂志,2026,35(01):42-46. DOI： 10.11659/jjssx.02E025130.

ZHANG Lin,ZHOU Xing-yu,LIU Yong,et al.Relief effects of three minimally invasive treatment methods on patients with postherpetic neuralgia[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2026,35(01):42-46. DOI： 10.11659/jjssx.02E025130.

摘要

目的

探讨神经阻滞（NB）、脉冲射频（PRF）和短时程脊髓电刺激（st-SCS）三种微创治疗方式对带状疱疹后神经痛（PHN）患者治疗效果的影响。

方法

分析2021年12月至2023年12月我院收治的204例PHN患者的资料，通过倾向性评分匹配均衡组间基线差异。根据治疗方式不同将患者分为NB组（

=67）、PRF组（

=14）、st-SCS组（

=47），比较各组一般资料。统计入院时、出院时、出院后4周各组患者疼痛数字评分法（NRS）评分及汉密尔顿抑郁评分（HAMD）；采用潜在类别增长模型分析疼痛轨迹。

结果

各治疗组患者的住院时间和抗抑郁药物服用情况存在统计学差异（

0.05）。其中，st-SCS组患者的住院时间最长，服用抗抑郁药物的占比最高。各治疗组患者不同时间点间NRS评分比较，差异均无统计学意义（

0.05）；各治疗组患者疼痛轨迹分布差异无统计学意义（

0.05）。各治疗组间不同时间点抑郁评分比较，差异均无统计学意义（

0.05）。

结论

NB、PRF、st-SCS三种微创治疗方式短期内对疼痛的缓解效果相当，但NB经济性更优，推荐作为初始治疗；st-SCS的住院时间相对较长，但适用于复杂且疼痛剧烈的患者。

Abstract

Objective

To investigate the treatment effects of three minimally invasive treatment methods neural blockade （NB）， pulsed radiofrequency （PRF）， and short-term spinal cord stimulation （st-SCS） on patients with postherpetic neuralgia （PHN）.

Methods

The data of 204 patients with PHN who were admitted to our hospital from December 2021 to December 2023 were analyzed， and the baseline differences among the groups were balanced by propensity score matching. Patients were divided into the NB group （

=67）， the PRF group （

=14）， and the st-SCS group （

=47） according to different treatment methods， and the general data were compared among groups. Pain numeric rating scale （NRS） scores and Hamilton depression rating scale （HAMD） scores at admission， discharge， and 4 weeks after dischar

ge of each group were recorded； a latent class growth model was used to analyze pain trajectories.

Results

There were statistically significant differences in the hospital stay and use of antidepressant among patients in each treatment group （

0.05）. Among them， patients in the st-SCS group had the longest hospital stay and the highest proportion of antidepressant administration. The NRS scores at different time points among patients in each treatment group showed no statistically significant differences （

0.05）. There was no statistically significant difference in the pain trajectory distribution among patients in each treatment group （

0.05）. The depression scores at different time points among patients in each treatment group also showed no statistically significant differences （

0.05）.

Conclusion

Three treatment methods NB，PRF and st-SCS show similar short-term effects in the relief of pain. However， NB may be more cost-effective and recommended as the initial treatment； st-SCS requires a relatively longer hospital stay but is suitable for patients with complex and severe pain.

关键词

Keywords

references

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