A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy

Meifang Yin; Yongming Li; Yongquan Luo; Mingzhou Yuan; Ubaldo Armato; Ilaria Dal Prà; Lijun Zhang; Dayong Zhang; Yating Wei; Guang Yang; Lixian Huang; Pin Wang; Jun Wu

doi:10.1093/burnst/tkab014

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A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy

更新时间：2022-06-14

- A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy
- Burns & Trauma Vol. 9, Issue 1, (2021)
- 作者机构：
  
  1. Department of Burn and Plastic Surgery
  2. The First Affiliated Hospital of Shenzhen University
  3. School of Microelectronics and Communication Engineering
  4. Chongqing University
  5. Institute of Fluid Physics
  6. China Academy of Engineering Physics
  7. Department of Burn Surgery
  8. Human Histology & Embryology Section
  9. University of Verona Medical School
- 作者简介：
- 基金信息：
- DOI：10.1093/burnst/tkab014
  CLC：
- Published：2021，
  
  Published Online：9 July 2021，
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Meifang Yin, Yongming Li, Yongquan Luo, Mingzhou Yuan, Ubaldo Armato, Ilaria Dal Prà, Lijun Zhang, Dayong Zhang, Yating Wei, Guang Yang, Lixian Huang, Pin Wang, Jun Wu, A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy, Burns & Trauma, Volume 9, 2021, tkab014, https://doi.org/10.1093/burnst/tkab014
DOI：

Meifang Yin, Yongming Li, Yongquan Luo, Mingzhou Yuan, Ubaldo Armato, Ilaria Dal Prà, Lijun Zhang, Dayong Zhang, Yating Wei, Guang Yang, Lixian Huang, Pin Wang, Jun Wu, A novel method for objectively, rapidly and accurately evaluating burn depth via near infrared spectroscopy, Burns & Trauma, Volume 9, 2021, tkab014, https://doi.org/10.1093/burnst/tkab014 DOI：

摘要

Abstract

The accurate and objective evaluation of burn depth is a significant challenge in burn wound care. Herein

we used near infrared spectroscopy (NIRS) technology to measure the different depth of thermal burns in ex vivo porcine models. Based on the intensity of the spectral signals and the diffuse reflection theory

we extracted the optical parameters involved in functional (total hemoglobin and water content) and structural (tissue scattered size and scattered particles) features that reflect the changes in burn depth. Next

we applied support vector regression to construct a model including the optical property parameters and the burn depth. Finally

we histologically verified the burn depth data collected via NIRS. The results showed that our inversion model could achieve an average relative error of about 7.63%

while the NIRS technology diagnostic accuracy was in the range of 50 μm. For the first time

this novel technique provides physicians with real-time burn depth information objectively and accurately.

关键词

Keywords

Burn depthNear infrared spectroscopySupport vector regression

references

1.Islam A, Ingrid S, Mats F, Folke S, Moustafa E. Use of the burn intervention score to calculate the charges of the care of burns. Burns. 2019;45:303–9.

2.Dissanaike S, Abdul-Hamed S, Griswold J. Variations in burn perfusion over time as measured by portable ICG fluorescence: a case series. Burns Trauma. 2014;2:201–5.

3.Khatib M, Jabir S, Fitzgerald O, Connor E, Philp B. A systematic review of the evolution of laser doppler techniques in burn depth assessment. Plast Surg Int. 2014;2014:621792. doi: 10.1155/2014/621792.

4.Monstrey S, Hoeksema H, Verbelen J, Pirayesh A, Blondeel P. Assessment of burn depth and burn wound healing potential. Burns. 2008;34:761–9.

5.Wang R, Zhao J, Zhang Z, Cao C, Zhang Y, Mao Y. Diagnostic accuracy of laser doppler imaging for the assessment of burn depth: a meta-analysis and systematic review. J Burn Care Res. 2020;41:619–25.

6.Deegan AJ, Mandell SP, Wang RK. Optical coherence tomography correlates multiple measures of tissue damage following acute burn injury. Quant Imag Med Surg. 2019;9:731–41.

7.Cross KM, Leonardi L, Payette JR, Gomez M, Levasseur MA, Schattka BJ, et al. Clinical utilization of near-infrared spectroscopy devices for burn depth assessment. Wound Repair Regen. 2007;15:332–40.

8.Dutta M, Bhalla AS, Guo R. THz imaging of skin burn: seeing the unseen—an overview. Adv Wound Care. 2016;5:338–48.

9.Mazhar A, Saggese S, Pollins AC, Cardwell NL, Nanney L, Cuccia DJ. Noncontact imaging of burn depth and extent in a porcine model using spatial frequency domain imaging. J Biomed Opt. 2014;19:086019. doi: 10.1117/1.

10.Nian YJ, Chen ZQ, Xue DD, Yin MF. Advances in the research of diagnosis techniques of burn depth. Chin J Burns. 2016;32:698–701.

11.Jan SN, Khan FA, Bashir MM, Nasir M, Ansari HH, Shami HB, et al. Comparison of laser doppler imaging (LDI) and clinical assessment in differentiating between superficial and deep partial thickness burn wounds. Burns. 2018;44:405–13.

12.Hoeksema H, Van de Sijpe K, Tondu T, Hamdi M, Van Landuyt K, Blondeel P, et al. Accuracy of early burn depth assessment by laser doppler imaging on different days post burn. Burns. 2009;35:36–45.

13.Sowa MG, Leonardi L, Payette JR, Fish JS, Mantsch HH. Near infrared spectroscopic assessment of hemodynamic changes in the early post-burn period. Burns. 2001;27:241–9.

14.Sowa MG, Leonardi L, Payette JR, Cross KM, Gomez M, Fish JS. Classification of burn injuries using near-infrared spectroscopy. J Biomed Opt. 2006;11:054002. doi: 10.1117/1.2362722.

15.Cross KM, Leonardi L, Gomez M, Freisen JR, Levasseur MA, Schattka BJ, et al. Noninvasive measurement of edema in partial thickness burn wounds. J Burn Care Res. 2009;30:807–17.

16.Zonios G, Perelman LT, Backman V, Manoharan R, Fitzmaurice M, Van Dam J, et al. Diffuse reflectance spectroscopy of human adenomatous colon polyps in vivo. Appl Opt. 1999;38:6628–37.

17.Prahl S. Hemoglobin absorption coefficient. Available at: http://omlc.ogi.edu/spectra/hemoglobin/index.html. (7 Sep 2020, date last accessed).

18.Palmer KF, Williams D. Optical properties of water in the near infrared. J Opt Soc Am. 1974;64:1107–10.

19.Chen D, Zeng N, Xie Q, He H, Tuchin VV, Ma H. Mueller matrix polarimetry for characterizing microstructural variation of nude mouse skin during tissue optical clearing. Biomed Opt Express. 2017;8:3559–3570.

20.Kim NS, Jin HY, Kim EY, Hong TH. Cystic duct variation detected by near-infrared fluorescent cholangiography during laparoscopic cholecystectomy. Ann Surg Treat Res. 2017;92:47–50.

21.McUmber H, Dabek RJ, Bojovic B, Driscoll DN. Burn depth analysis using indocyanine green fluorescence: a review. J Burn Care Res. 2019;40:513–6.

22.Goertz O, Ring A, Köhlinger A, Daigeler A, Andree C, Steinau H, et al. Orthogonal polarization spectral imaging. Ann Plas Surg. 2010;64:217–21.

23.Lin Y, Huang C, Wang S. Quantitative assessments of burn degree by high-frequency ultrasonic backscattering and statistical model. Phys Ned Biol. 2011;56:757–73.

24.Mustari A, Kanie T, Kawauchi S, Sato S, Sato M, Kokubo Y, et al. In vivo evaluation of cerebral hemodynamics and tissue morphology in rats during changing fraction of inspired oxygen based on spectrocolorimetric imaging technique. Int J Mol Sci. 2018;19:491. doi: 10.3390/ijms19020491.

25.Zhen-huan F, Xia-ping F, Xue-ming H. Investigation of absorption and scattering characteristics of kiwifruit tissue using a single integrating sphere system. J Zhejiang Univ Sci B. 2016;17:484–492.

26.Taroni P, Paganoni AM, Ieva F, Pifferi A, Quarto G, Abbate F, et al. Non-invasive optical estimate of tissue composition to differentiate malignant from benign breast lesions: a pilot study. Sci Rep-UK. 2017;7:40683. doi: 10.1038/srep40683.

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