Comorbidities of scars in China: a national study based on hospitalized cases

Weishi Kong; Yongqiang Xiao; Baoli Wang; Zhe Zhu; Lunyang Hu; Hongtai Tang; Kangan Wang; He Fang; Ying Shi; Jianyan Long; Lanxia Gan; Haibo Wang; Yu Sun; Zhaofan Xia

doi:10.1093/burnst/tkab012

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Comorbidities of scars in China: a national study based on hospitalized cases

更新时间：2022-06-14

- Comorbidities of scars in China: a national study based on hospitalized cases
- Burns & Trauma Vol. 9, Issue 1, (2021)
- 作者机构：
  
  1. Department of Burn Surgery
  2. Burn Institute of PLA
  3. Department of Burn and Plastic Surgery, The 970th Hospital of People's Liberation Army
  4. China Standard Medical Information Research Centre
- 作者简介：
- 基金信息：
- DOI：10.1093/burnst/tkab012
  CLC：
- Published：2021，
  
  Published Online：10 June 2021，
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Weishi Kong, Yongqiang Xiao, Baoli Wang, Zhe Zhu, Lunyang Hu, Hongtai Tang, Kangan Wang, He Fang, Ying Shi, Jianyan Long, Lanxia Gan, Haibo Wang, Yu Sun, Zhaofan Xia, Comorbidities of scars in China: a national study based on hospitalized cases, Burns & Trauma, Volume 9, 2021, tkab012, https://doi.org/10.1093/burnst/tkab012
DOI：

Weishi Kong, Yongqiang Xiao, Baoli Wang, Zhe Zhu, Lunyang Hu, Hongtai Tang, Kangan Wang, He Fang, Ying Shi, Jianyan Long, Lanxia Gan, Haibo Wang, Yu Sun, Zhaofan Xia, Comorbidities of scars in China: a national study based on hospitalized cases, Burns & Trauma, Volume 9, 2021, tkab012, https://doi.org/10.1093/burnst/tkab012 DOI：

摘要

Abstract

BackgroundScar comorbidities seriously affect the physical and mental health of patients

but few studies have reported the exact epidemiological characteristics of scar comorbidities in China. This study aimed to investigate the prevalence of scar comorbidities in China.MethodsThe data of 177

586 scar cases between 2013 and 2018 were obtained from the Hospital Quality Monitoring System based on the 10th edition of the International Classification of Diseases coding system. The total distribution of scar comorbidities and their relationship with age

aetiology and body regions were analysed.ResultsSix comorbidities (contracture

malformation

ocular complications

adhesion

infection and others) were the main focus. In general

male patients outnumbered females and urban areas outnumbered rural areas. The proportion of contractures was the highest at 59

028 (33.24%). Students

workers and farmers made up the majority of the occupation. Han Chinese accounted for the majority of the ethnic. The highest proportion of scar contracture occurred at 1–1.9 years of age (58.97%)

after which a significant downward trend was observed. However

starting from 50 years of age

ocular complications increased gradually and significantly

eventually reaching a peak of 34.49% in those aged >80 years. Scar contracture was the most common comorbidity according to aetiology

and the highest proportion was observed in patients who were scalded (29.33%). Contractures were also the most frequent comorbidity in hands (10.30%)

lower limbs (6.97%)

feet (6.80%) and upper limbs (6.02%). The mean and median hospitalization durations were 12.85 and 8 days

respectively.ConclusionsContractures were the most common comorbidities

and different comorbidities tended to occur at different ages and with different causative factors.

关键词

Keywords

ScarEpidemiologyAetiologyComorbidityChinese Hospital Quality Monitoring SystemHospitalization

references

1.Jia Z, Ding F, Wu Y, He Q, Ruan D. The 50 most-cited articles in orthopaedic surgery from Mainland China. Clin Orthop Relat Res. 2015;473:2423–30.

2.Dong C, Zhu M, Huang L, Liu W, Liu H, Jiang K, et al. Risk factors for tissue expander infection in scar reconstruction: a retrospective cohort study of 2374 consecutive cases. Burns Trauma. 2021;8:tkaa037.

3.Ledon JA, Savas J, Franca K, Chacon A, Nouri K. Intralesional treatment for keloids and hypertrophic scars: a review. Dermatol Surg. 2013;39:1745–57.

4.Rabello FB, Souza CD, Farina Júnior JA. Update on hypertrophic scar treatment. Clin (S Paulo). 2014;69:565–73.

5. Lee HJ, Jang YJ. Recent understandings of biology, prophylaxis and treatment strategies for hypertrophic scars and Keloids. Int J Mol Sci. 2018;19.

6.Trace AP, Enos CW, Mantel A, Harvey VM. Keloids and hypertrophic scars: A spectrum of clinical Challenges. Am J Clin Dermatol. 2016;17:201–23.

7.Finnerty CC, Jeschke MG, Branski LK, Barret JP, Dziewulski P, Herndon DN. Hypertrophic scarring: The greatest unmet challenge after burn injury. Lancet. 2016;388:1427–36.

8.Brewin MP, Homer SJ. The lived experience and quality of life with burn scarring-the results from a large-scale online survey. Burns. 2018;44:1801–10.

9.Bijlard E, Kouwenberg CA, Timman R, Hovius SE, Busschbach JJ, Mureau MA. Burden of keloid disease: A cross-sectional health-related quality of life Assessment. Acta Derm Venereol. 2017;97:225–9.

10.Gibson JAG, Ackling E, Bisson JI, Dobbs TD, Whitaker IS. The association of affective disorders and facial scarring: Systematic review and meta-analysis. J Affect Disord. 2018;239:1–10.

11.Fan X, Ma B, Zeng D, Fang X, Li H, Xiao S, et al. Burns in a major burns center in East China from 2005 to 2014: Incidence and outcome. Burns. 2017;43:1586–95.

12.Li H, Yao Z, Tan J, Zhou J, Li Y, Wu J, et al. Epidemiology and outcome analysis of 6325 burn patients: A five-year retrospective study in a major burn center in Southwest China [sci. rep.]. Sci Rep. 2017;7:46066.

13.Lu WS, Zheng XD, Yao XH, Zhang LF. Clinical and epidemiological analysis of keloids in Chinese patients. Arch Dermatol Res. 2015;307:109–14.

14.Wang KA, Sun Y, Wu GS, Wang YR, Xia ZF. Epidemiology and outcome analysis of hand burns: A 5-year retrospective review of 378 cases in a burn center in Eastern China. Burns. 2015;41:1550–5.

15.Noishiki C, Hayasaka Y, Ogawa R. Sex differences in Keloidogenesis: An analysis of 1659 keloid patients in Japan. Dermatol Ther Heidelb. 2019;9:747–54.

16.Lu L, Xiong W, Yang X, Ma X, Wang C, Yan B, et al. In-hospital mortality of status epilepticus in China: Results from a nationwide survey. Seizure. 2020;75:96–100.

17.Sunil NP, Ahmed F, Jash PK, Gupta M, Suba S. Study on surgical management of post burn hand Deformities. J Clin Diagn Res. 2015;9:C6–CC10.

18.Keserü M, Dulz S, Wolf A, Green S, Press U, Schaudig U. Postoperative care and options for scar treatment in eyelid surgery. Ophthalmologe. 2018;115:283–92.

19.Schouten HJ, Nieuwenhuis MK, van Baar ME, van der Schans CP, Niemeijer AS, van Zuijlen PPM. The prevalence and development of burn scar contractures: A prospective multicenter cohort study. Burns. 2019;45:783–90.

20. Moradi Tuchayi S, Makrantonaki E, Ganceviciene R, Dessinioti C, Feldman SR, Zouboulis CC. Acne vulgaris. Nat Rev Dis Primers. 2015;1:15029.

21.Oosterwijk AM, Mouton LJ, Schouten H, Disseldorp LM, van der Schans CP, Nieuwenhuis MK. Prevalence of scar contractures after burn: A systematic review. Burns. 2017;43:41–9.

22.Kim B, Sgarioto M, Hewitt D, Paver R, Norman J, Fernandez-Penas P. Scar outcomes in dermatological surgery. Australas J Dermatol. 2018;59:48–51.

23.Khansa I, Harrison B, Janis JE. Evidence-based scar management: How to improve results with technique and Technology. Plast Reconstr Surg. 2016;138;Suppl:165S–78

24.Sano H, Hokazono Y, Ogawa R. Distensibility and gross elasticity of the skin at various body sites and association with pathological scarring: A case Study. J Clin Aesthet Dermatol. 2018;11:15–8.

25.Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, Hunt TK, et al. Human skin wounds: A major and snowballing threat to public health and the economy. Wound Repair Regen. 2009;17:763–71.

26.Lancerotto L, Sferrazza R, Amabile A, Azzena B. Burn care in relation to burn epidemiology in Italy. Burns. 2011;37:835–41.

27.Iqbal T, Saaiq M, Ali Z. Epidemiology and outcome of burns: Early experience at the country’s first national burns centre. Burns. 2013;39:358–62.

28.Stone II R, Natesan S, Kowalczewski CJ, Mangum LH, Clay NE, Clohessy RM, et al. Advancements in regenerative strategies through the continuum of burn care. Front Pharmacol. 2018;9:672.

29.Zhu L, Zhang H, Shi F, Yi D, Zhu G. Epidemiology and outcome analysis of scalds in children caused by “guo lian kang”: An 11-year review in a burn center in China. Burns. 2015;41:289–96.

30.Wang W, Zhou Y, Zeng J, Shi M, Chen B. Epidemiology and clinical characteristics of patients hospitalized for ocular trauma in South-Central China. Acta Ophthalmol. 2017;95:e503–10.

31.Raczyńska D, Glasner L, Serkies-Minuth E, Wujtewicz MA, Mitrosz K. Eye surgery in the elderly. Clin Interv Aging. 2016;11:407–14.

32.Wang Y, Grenell A, Zhong F, Yam M, Hauer A, Gregor E, et al. Metabolic signature of the aging eye in mice. Neurobiol Aging. 2018;71:223–33.

33.Brusselaers N, Monstrey S, Vogelaers D, Hoste E, Blot S. Severe burn injury in Europe: A systematic review of the incidence, etiology, morbidity, and mortality. Crit Care. 2010;14:R188.

34.Richards WT, Vergara E, Dalaly DG, Coady-Fariborzian L, Mozingo DW. Acute surgical management of hand burns. J Hand Surg Am. 2014;39:2075–2085.e2.

35.Bhattacharya S. Avoiding unfavorable results in postburn contracture hand. Indian J Plast Surg. 2013;46:434–44.

36.Eming SA, Martin P, Tomic-Canic M. Wound repair and regeneration: Mechanisms, signaling, and translation. Sci Transl Med. 2014;6:265sr6.

37.Mofazzal Jahromi MA, Sahandi Zangabad P, Moosavi Basri SM, Sahandi Zangabad K, Ghamarypour A, Aref AR, et al. Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing. Adv Drug Deliv Rev. 2018;123:33–64.

38.Kalasho BD, Kikuchi R, Zoumalan CI. Silicone-based scar cream for post upper eyelid blepharoplasty-associated cicatricial and hypertrophic Scarring. J Drugs Dermatol. 2019;18:440–6.

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