The association between vitamin D levels and burn factors in different burn types

Yoon Soo Cho; Cheong Hoon Seo; So Young Joo; Suk Hoon Ohn

doi:10.1093/burnst/tkaa018

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The association between vitamin D levels and burn factors in different burn types

更新时间：2022-06-09

- The association between vitamin D levels and burn factors in different burn types
- Burns & Trauma Vol. 8, Issue 1, (2020)
- 作者机构：
  
  1. Department of Rehabilitation Medicine, Burn Center, Hangang Sacred Heart Hospital
  2. Department of Physical Medicine and Rehabilitation, Hallym University Sacred Heart Hospital
- 作者简介：
- 基金信息：
- DOI：10.1093/burnst/tkaa018
  CLC：
- Published：2020，
  
  Published Online：19 June 2020，
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Yoon Soo Cho, Cheong Hoon Seo, So Young Joo, Suk Hoon Ohn, The association between vitamin D levels and burn factors in different burn types, Burns & Trauma, Volume 8, 2020, tkaa018, https://doi.org/10.1093/burnst/tkaa018
DOI：

Yoon Soo Cho, Cheong Hoon Seo, So Young Joo, Suk Hoon Ohn, The association between vitamin D levels and burn factors in different burn types, Burns & Trauma, Volume 8, 2020, tkaa018, https://doi.org/10.1093/burnst/tkaa018 DOI：

摘要

Abstract

BackgroundPatients with burns present with different clinical features depending on the types of burn injury and burn patients with lower levels of vitamin D have worse prognoses and more complications. The study aims to investigate the association between vitamin D levels and burn factors according to each burn type in relation to early intensive rehabilitation therapy initiated for inpatients with burns.MethodsIn this retrospective study

we enrolled 757 of 1716 inpatients who underwent rehabilitative therapy between May 2013 and April 2017. Burn types were divided into flame burn

electrical burn and other burns

including scalding

contact and chemical burns. Age

burned body surface area (BSA)

wound healing time (WHT)

length of hospital stay (LOS) and body mass index were analysed between vitamin D deficient and non-deficient patient groups using Student’s t-tests

or Mann-Whitney U test and among three burn types using one-way analysis of variance (ANOVA) or Kruskal-Wallis one-way ANOVA. The relationship between vitamin D levels and burn factors was evaluated using Pearson's or Spearman's correlation coefficient tests

and multiple linear regression analysis in different burn groups.ResultsIn total

88.9% patients were vitamin D deficient

and these patients had a larger burned BSA (p = 0.015) and longer WHT and LOS (all p < 0.001) than non-deficient patients. Burned BSA

WHT and vitamin D levels showed significant differences in their mean values according to three burn types (all p < 0.001). WHT was a communal factor significantly associated with vitamin D levels in all three burn types (p < 0.05). The WHT cut-off points to predict vitamin D deficiency were 55 days for flame burn (p < 0.001) and 62.5 days for electrical burn (p = 0.001).ConclusionsWHT across all three burn types was a common factor associated with vitamin D levels for inpatients with burns who had undergone rehabilitative therapy. Electrical burn patients with vitamin D deficiency

even those with a low burned BSA percentage

showed prolonged wound healing over a two-month post-burn period. Independent of burned BSA

nutritional intervention concerning vitamin D in relation to burn wound healing should be considered to guide early initiation of intensive rehabilitation therapy.

关键词

Keywords

Burn factorsVitamin D deficiencyBurn typeWound healing timeRehabilitation

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