Pengfei Zheng, Yunhua Liu, Xinjiang Zhang, et al. Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease. [J]. Genes & Diseases 10(2).(2023)
DOI:
Pengfei Zheng, Yunhua Liu, Xinjiang Zhang, et al. Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease. [J]. Genes & Diseases 10(2).(2023) DOI: 10.1016/j.jtcms.2023.01.002.
Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease
摘要
Abstract
ObjectiveTo explore the kidney yang deficiency pattern (KYDP) in a chronic kidney disease (CKD) rat model and the mechanisms underlying the effects of Zhenwu decoction (ZWD) by conducting transcriptomic and metabolomic analyses.
关键词
Keywords
Chronic kidney diseaseKidney yang deficiency patternZhenwu decoctionTranscriptomicsMetabolomics
Tetratricopeptide repeat domain 36 deficiency mitigates renal tubular injury by inhibiting TGF-β1-induced epithelial–mesenchymal transition in a mouse model of chronic kidney disease
Hypercalciuria switches Ca2+ signaling in proximal tubular cells, induces oxidative damage to promote calcium nephrolithiasis
Metabolomic studies in the inborn error of metabolism alkaptonuria reveal new biotransformations in tyrosine metabolism
Related Author
Qin Zhou
Qianyin Li
Qingling He
Lei Chen
Yilu Ni
Rui Peng
Xin Yan
Samuel Shin
Related Institution
The Ministry of Education Key Laboratory of Clinical Diagnostics, School of Laboratory Medicine, Chongqing Medical University
Calcium Signaling Laboratory, Research Service, Veterans Affairs Medical Center, 50 Irving Street,,, DC
Institute of Life Course and Medical Sciences, University of Liverpool, William Henry Duncan Building, 6 West Derby Street
Department of Clinical Biochemistry & Metabolic Medicine, Liverpool Clinical Laboratories, Royal Liverpool University Hospital, Prescot Street
School of Sport & Exercise Sciences, Liverpool John Moores University, Tom Reilly Building, Byrom Street