1. Research Center of Traditional Chinese Medicine and Clinical Pharmacy, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University,Shandong,Jinan,China,250014

2. Key Laboratory of Marine Drugs, Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China,Shandong,Qingdao,China,266003

3. Innovation Platform of Marine Drug Screening & Evaluation, Qingdao National Laboratory for Marine Science and Technology,Shandong,Qingdao,China,266100

4. College of Marine Life Sciences, Ocean University of China,Shandong,Qingdao,China,266071

5. Department of Urology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University,Shandong,Yantai,China,264000

6. Department of Neuroscience, University of Michigan,MI,Ann Arbor,USA,48103