1. Center for Traditional Chinese Medicine and Gut Microbiota, Minhang Hospital, Fudan University,Shanghai,China,201100

2. Key Laboratory of Cell Differentiation and Apoptosis of Chinese Minister of Education, Department of Pathophysiology, Shanghai Jiao Tong University School of Medicine,Shanghai,China,200025

3. Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine,Shanghai,China,200025

4. Department of Molecular and Cellular Biochemistry, Markey Cancer Center, University of Kentucky College of Medicine,KY,Lexington,USA,40506

5. Medical Research Center, Binzhou Medical University Hospital,Shandong,Binzhou,China,256600

6. Department of Radiation Oncology, Yantai Affiliated Hospital of Binzhou Medical University,Shandong,Yantai,China,264100

7. Department of Pathology, Kunming Medical University,Yunnan,Kunming,China,650500

8. Department of Physiology, School of Basic Medical Sciences, Weifang Medical University,Shandong,Weifang,China,261021

9. Peninsular Cancer Center, Binzhou Medical University,Shandong,Yantai,China,264003

10. Department of Thoracic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University,Shanghai,China,200030

11. Department of Respiratory Medicine, The Second Affiliated Hospital, Dalian Medical University,Liaoning,Dalian,China,116023

12. Department of Pathology, Molecular Pathology Research Center, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,China,100730

13. Department of Laboratory Medicine, Shanghai Pulmonary Hospital Affiliated Tongji University,Shanghai,China,200080