The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer

Jiyan Wang; Tao He; Qingle Gao; Hongkai Chang; Xintong Dai; Juze Yang; Shuangping Liu; Shuai Zhang; Changliang Shan; Chunze Zhang

doi:10.1016/j.gendis.2023.03.026

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The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer

Short communication | 更新时间：2024-02-04

- The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer
- Genes & Diseases Vol. 11, Issue 2, (2024)
- 作者机构：
  
  1. Department of Pathology, Medical School, Dalian University,Liaoning,Dalian,China,116622
  2. State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research, Nankai University,Tianjin,China,300350
  3. School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine,Tianjin,China,301617
  4. Department of Respiratory Medicine, Sir Run Run Shaw Hospital and Institute of Translational Medicine, Zhejiang University School of Medicine,Zhejiang,Hangzhou,China,310016
  5. Department of Colorectal Surgery, Tianjin Union Medical Center, Nankai University,Tianjin,China,300121
  6. Departments of Pathology, Characteristic Medical Center of The Chinese People's Armed Police Force,Tianjin,China,300162
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.03.026
  CLC：
- Published：2024，
  
  Published Online：1 March 2024，
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Jiyan Wang, Tao He, Qingle Gao, et al. The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer. [J]. Genes & Diseases 11(2).(2024)
DOI：

Jiyan Wang, Tao He, Qingle Gao, et al. The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer. [J]. Genes & Diseases 11(2).(2024) DOI： 10.1016/j.gendis.2023.03.026.

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The dysfunctional Wnt pathway down-regulates MLH1/SET expression and promotes microsatellite instability and immunotherapy response in colorectal cancer

DOI：10.1016/j.gendis.2023.03.026

摘要

Abstract

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Keywords

references