1. Department of Cell Biology, Yale University School of Medicine,CT,New Haven,USA,06520

2. Institute of Pharmacology, College of Pharmaceutical Science, Zhejiang University of Technology,Zhejiang,Hangzhou,China,310014

3. Department of Endocrinology, Children's Hospital of Zhejiang University School of Medicine, National Clinical Research Center for Children's Health,Zhejiang,Hangzhou,China,310051

4. Department of Endocrinology, The Affiliated Sir Run Run Shaw Hospital, Zhejiang University School of Medicine,Zhejiang,Hangzhou,China,310016

5. Binjiang Institute of Zhejiang University,Zhejiang,Hangzhou,China,310053

6. Department of Biomedical Engineering, Key Laboratory of Biomedical Engineering of Ministry of Education, State Key Laboratory of Modern Optical Instrumentation, Zhejiang Provincial Key Laboratory of Cardio-Cerebral Vascular Detection Technology and Medicinal Effectiveness Appraisal, Zhejiang University,Zhejiang,Hangzhou,China,310027