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Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways
Short communication | 更新时间：2023-08-29

    • Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways

    • Genes & Diseases   Vol. 10, Issue 5, (2023)
    • 作者机构：

      1. Liverpool University Hospitals NHS Foundation Trust, Clinical Biochemistry and Metabolic Medicine, Liverpool L3 5PS, United Kingdom

      2. Ghent University, Department of Biomolecular Medicine, Ghent,Belgium,9052

      3. Vrije Universiteit Brussel, In Vitro Liver Disease Modelling Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103,B,Brussels,Belgium,1090

      4. University of Liverpool, Dept. of Musculoskeletal & Ageing Science, Institute of Life Course & Medical Sciences, Liverpool L7 8TX, United Kingdom

      5. Vrije Universiteit Brussel, Liver Therapy & Evolution Team, In Vitro Toxicology and Dermato-Cosmetology (IVTD) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103,B,Brussels,Belgium,1090

      6. Vrije Universiteit Brussel, Interfaculty Center Data Processing and Statistics, Faculty of Medicine and Pharmacy, Laarbeeklaan 103,B,Brussels,Belgium,1090

      7. Université Libre de Bruxelles, Laboratoire de Pédiatrie,B,Brussels,Belgium,1050

      8. Vrije Universiteit Brussel, Experimental Pharmacology (EFAR) Research Group, Faculty of Medicine and Pharmacy, Laarbeeklaan 103,B,Brussels,Belgium,1090

      9. AZ Delta General Hospital, Department of Laboratory Medicine, Roeselare,Belgium,8800

    • DOI：10.1016/j.gendis.2022.11.013    

      CLC：

    • Published：2023，

      Published Online：1 September 2023，

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  • Colemonts-Vroninks Haaike, Norman P. Brendan, Van Laere Sven, et al. Short-term nitisinone discontinuation of hereditary tyrosinemia type 1 mice causes metabolic alterations in glutathione metabolism/biosynthesis and multiple amino acid degradation pathways. [J]. Genes & Diseases 10(5).(2023) DOI： 10.1016/j.gendis.2022.11.013.

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