lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology

Chunlin Ou; Xiaoyun He; Yong Liu; Xin Zhang

doi:10.1016/j.gendis.2021.08.012

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lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology

更新时间：2023-05-16

- lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology
- Genes & Diseases Vol. 10, Issue 2, (2023)
- 作者机构：
  
  1. Clinical Research Center for Pharyngolaryngeal Diseases and Voice Disorders in Hunan Province,Hunan,Changsha,China,410008
  2. Departments of Ultrasound Imaging, Xiangya Hospital, Central South University,Hunan,Changsha,China,410008
  3. Department of Otolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University,Hunan,Changsha,China,410008
  4. Otolaryngology Major Disease Research, Key Laboratory of Hunan Province,Hunan,Changsha,China,410008
  5. National Clinical Research Center for Geriatric Disorders (Xiangya Hospital),Hunan,Changsha,China,410008
  6. Department of Pathology, Xiangya Hospital, Central South University,Hunan,Changsha,China,410008
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2021.08.012
  CLC：
- Published：2023，
  
  Published Online：1 March 2023，
扫描看全文
Chunlin Ou, Xiaoyun He, Yong Liu, et al. lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology. [J]. Genes & Diseases 10(2).(2023)
DOI：

Chunlin Ou, Xiaoyun He, Yong Liu, et al. lncRNA cytoskeleton regulator RNA (CYTOR): Diverse functions in metabolism, inflammation and tumorigenesis, and potential applications in precision oncology. [J]. Genes & Diseases 10(2).(2023) DOI： 10.1016/j.gendis.2021.08.012.

摘要

Abstract

Long non-coding RNAs (lncRNAs) are a novel class of non-coding RNA (ncRNA)

that have been studied extensively in the field of tumor research in recent years. In the case of tumor-associated lncRNAs

lncRNA cytoskeleton regulator RNA (

CYTOR

) displays extensive functions in tumorigenesis

including invasion

metastasis

malignant proliferation

glycolysis

and inflammatory response. Moreover

the dysregulation of

CYTOR

is closely related to clinicopathological characteristics

such as tumor stage

lymph node metastasis and infiltration

and poor prognosis of tumor patients. In this review

we provide a novel strategy to summarize the biological functions and clinical value of

CYTOR

in tumors through an overview of the literature combined with gene set enrichment analysis. A deeper understanding of the role of

CYTOR

in tumorigenesis may provide new diagnostic

prognostic and therapeutic markers for human tumors.

关键词

Keywords

CYTORGSEAInflammationlncRNAsTherapyTumorigenesis

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