Xia Liao, Yang Bu, Qingan Jia. Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future. [J]. Genes & Diseases 7(3).(2020)
DOI:
Xia Liao, Yang Bu, Qingan Jia. Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future. [J]. Genes & Diseases 7(3).(2020) DOI: 10.1016/j.gendis.2019.10.016.
Traditional Chinese medicine as supportive care for the management of liver cancer: Past, present, and future
摘要
Abstract
Liver cancer is the sixth most commonly diagnosed cancer and the fourth leading cause of cancer death worldwide. Western medicine and therapies are the primary treatment strategies of hepatocellular carcinoma (HCC)
but the general prognosis for HCC patients is still dismal. Under these circumstances
HCC prevention is particularly important. Traditional Chinese medicine (TCM) encompasses a wealth of documented therapeutic resources
and “preventative treatment” is the principle of TCM. In China
TCM has been used for HCC prevention for thousands of years
and has also been demonstrated to be effective for the treatment of HCC in modern China. However
the TCM theory for prevention and treatment of HCC is more widely accepted in China than abroad. In this review
we first summarize the herbs and ancient formulas with therapeutic effects on HCC. We also review the research status of TCM in modern medicine as well as the current obstacles in its development. Finally
we discuss the future of TCM in the context of precision and integrated medicine. After reviewing the literature
we believe that TCM
through ancient development
is an advanced method of cancer treatment with positive curative effects
despite its surrounding controversy. Furthermore
precise analyses and systematic research methods provides novel approaches to modernize TCM for the future.
关键词
Keywords
Chinese herbal medicineHepatocellular carcinomaMolecular mechanismNetwork pharmacologyTraditional Chinese medicine
The paradoxical functions of long noncoding RNAs in hepatocellular carcinoma: Implications in therapeutic opportunities and precision medicine
IGF2BPs as novel m6A readers: Diverse roles in regulating cancer cell biological functions, hypoxia adaptation, metabolism, and immunosuppressive tumor microenvironment
LRP1B suppresses HCC progression through the NCSTN/PI3K/AKT signaling axis and affects doxorubicin resistance
Application of evidence-based medicine methods in integrative oncology research
Current status of outcome reporting in randomized controlled trials of traditional Chinese medicine for mammary gland hyperplasia: A systematic review
Related Author
Duguang Li
Xiaoxiao Fan
Yirun Li
Jing Yang
Hui Lin
Xiaofeng Jiang
Meiqi Duan
Haiyang Liu
Related Institution
Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Department of Gastroendoscopy, The Fourth Affiliated Hospital of China Medical University
Department of Rheumatology and Immunology, The First Affiliated Hospital of China Medical University
Department of General Surgery, The Fourth Affiliated Hospital of China Medical University